13.09729 % | Fidelity Management & Research Company LLC | 1,56,26,378 | 20,54,142 | 30/6/2024 |
9.04989 % | T. Rowe Price Associates, Inc. | 1,07,97,421 | 35,02,039 | 30/6/2024 |
6.94231 % | RTW Investments L.P. | 82,82,870 | -5,23,968 | 22/8/2024 |
5.98499 % | BlackRock Institutional Trust Company, N.A. | 71,40,692 | 16,69,713 | 30/6/2024 |
5.45218 % | Avoro Capital Advisors LLC | 65,05,000 | 6,80,000 | 30/6/2024 |
4.96703 % | The Vanguard Group, Inc. | 59,26,169 | 20,96,174 | 30/6/2024 |
4.52637 % | RA Capital Management, LP | 54,00,408 | 5,04,449 | 30/6/2024 |
4.29897 % | TD Cowen (Research) | 51,29,103 | -5,00,000 | 30/6/2024 |
4.25388 % | Bristol Myers Squibb | 50,75,304 | 50,75,304 | 27/11/2023 |
3.18668 % | Wellington Management Company, LLP | 38,02,026 | 25,73,028 | 30/6/2024 |
3.06499 % | Janus Henderson Investors | 36,56,843 | 24,14,010 | 30/6/2024 |
2.84719 % | Adage Capital Management, L.P. | 33,96,982 | 9,96,937 | 30/6/2024 |
2.78268 % | State Street Global Advisors (US) | 33,20,019 | -1,41,803 | 30/6/2024 |
1.89146 % | Geode Capital Management, L.L.C. | 22,56,697 | 6,57,023 | 30/6/2024 |
1.74742 % | Casdin Capital, LLC | 20,84,841 | 0 | 30/6/2024 |
1.59422 % | Artisan Partners Limited Partnership | 19,02,065 | -4,24,436 | 30/6/2024 |
1.44781 % | Boxer Capital, L.L.C. | 17,27,388 | 0 | 30/6/2024 |
1.00482 % | Nuveen LLC | 11,98,852 | 1,28,111 | 30/6/2024 |
0.93379 % | Polar Capital LLP | 11,14,101 | 11,14,101 | 30/6/2024 |
0.87855 % | Morgan Stanley & Co. LLC | 10,48,194 | -3,51,199 | 30/6/2024 |
0.70341 % | BlackRock Financial Management, Inc. | 8,39,235 | 6,00,535 | 30/6/2024 |
0.66475 % | Charles Schwab Investment Management, Inc. | 7,93,117 | 2,44,682 | 30/6/2024 |
0.63496 % | EcoR1 Capital, LLC | 7,57,576 | 0 | 30/6/2024 |
0.61943 % | D. E. Shaw & Co., L.P. | 7,39,039 | 7,07,773 | 30/6/2024 |
0.59213 % | OrbiMed Advisors, LLC | 7,06,475 | -2,87,625 | 30/6/2024 |
0.58090 % | Dimensional Fund Advisors, L.P. | 6,93,066 | -3,17,102 | 30/6/2024 |
0.57007 % | Northern Trust Investments, Inc. | 6,80,150 | 82,692 | 30/6/2024 |
0.54946 % | Invus Public Equities Advisors, LLC | 6,55,555 | 6,55,555 | 30/6/2024 |
0.54116 % | Woodline Partners LP | 6,45,658 | 59,320 | 30/6/2024 |
0.44646 % | Fidelity Institutional Asset Management | 5,32,669 | -1,36,731 | 30/6/2024 |
0.43394 % | SilverArc Capital Management, LLC | 5,17,734 | 28,431 | 30/6/2024 |
0.43026 % | TD Asset Management Inc. | 5,13,338 | 3,00,054 | 30/6/2024 |
0.42201 % | Alethea Capital Management, LLC | 5,03,504 | -2,57,193 | 30/6/2024 |
0.39824 % | Two Sigma Investments, LP | 4,75,146 | -2,26,054 | 30/6/2024 |
0.35621 % | Cormorant Asset Management, LP | 4,25,000 | 4,25,000 | 30/6/2024 |
0.35301 % | Goldman Sachs & Company, Inc. | 4,21,182 | 40,446 | 30/6/2024 |
0.34728 % | Lord, Abbett & Co. LLC | 4,14,340 | 4,14,340 | 30/6/2024 |
0.31833 % | Pictet Asset Management Ltd. | 3,79,802 | 3,68,930 | 30/6/2024 |
0.31632 % | Renaissance Technologies LLC | 3,77,400 | 3,77,400 | 30/6/2024 |
0.31508 % | Eventide Asset Management, LLC | 3,75,924 | 3,75,924 | 30/6/2024 |
0.30402 % | JPMorgan Asset Management U.K. Limited | 3,62,732 | -69,715 | 30/6/2024 |
0.27106 % | Candriam Luxembourg S.A. | 3,23,396 | 0 | 30/9/2024 |
0.26678 % | Invesco Capital Management LLC | 3,18,293 | -25,417 | 30/6/2024 |
0.24348 % | Norges Bank Investment Management (NBIM) | 2,90,500 | 2,05,400 | 31/3/2023 |
0.23586 % | BlackRock Investment Management, LLC | 2,81,410 | 75,900 | 30/6/2024 |
0.22862 % | Manulife Investment Management (North America) Limited | 2,72,762 | 42,636 | 30/6/2024 |
0.22521 % | Levin (Arthur A.) | 2,68,702 | 0 | 21/10/2024 |
0.21067 % | BNY Mellon Asset Management | 2,51,354 | 75,981 | 30/6/2024 |
0.18817 % | Voya Investment Management LLC | 2,24,503 | 1,99,982 | 30/6/2024 |
0.18123 % | AllianceBernstein L.P. | 2,16,228 | -1,12,298 | 30/6/2024 |
0.16777 % | UBS Asset Management (Americas), Inc. | 2,00,170 | 1,82,963 | 30/6/2024 |
0.16763 % | Darwin Global Management Ltd | 2,00,000 | 2,00,000 | 30/6/2024 |
0.16525 % | Boyce (Sarah) | 1,97,164 | 92,120 | 23/9/2024 |
0.16355 % | Parametric Portfolio Associates LLC | 1,95,131 | 59,706 | 30/6/2024 |
0.16055 % | Bessemer Trust Company, N.A. (US) | 1,91,553 | -1,23,181 | 31/7/2024 |
0.15665 % | Mirae Asset Global Investments (USA) LLC | 1,86,896 | 1,49,434 | 30/6/2024 |
0.15443 % | Mutual of America Capital Management LLC | 1,84,249 | 40,913 | 30/6/2024 |
0.15440 % | New York State Common Retirement Fund | 1,84,213 | 63,843 | 30/9/2024 |
0.15326 % | BofA Global Research (US) | 1,82,854 | 1,183 | 30/6/2024 |
0.14961 % | Propel Bio Management, LLC | 1,78,500 | 0 | 30/6/2024 |
0.13799 % | American Century Investment Management, Inc. | 1,64,631 | 25,663 | 30/6/2024 |
0.13581 % | Jane Street Capital, L.L.C. | 1,62,039 | 50,125 | 30/6/2024 |
0.13476 % | Citadel Advisors LLC | 1,60,777 | 57,644 | 30/6/2024 |
0.13208 % | BlackRock Advisors (UK) Limited | 1,57,588 | 13,939 | 30/9/2024 |
0.13139 % | Raymond James & Associates, Inc. | 1,56,763 | 3,131 | 30/9/2024 |
0.13109 % | Schweizerische Nationalbank | 1,56,400 | 15,600 | 30/6/2024 |
0.12572 % | Alyeska Investment Group, L.P. | 1,50,000 | 1,50,000 | 30/6/2024 |
0.11858 % | Rhumbline Advisers Ltd. Partnership | 1,41,481 | 22,604 | 30/6/2024 |
0.11067 % | Voloridge Investment Management, LLC | 1,32,041 | 1,32,041 | 30/6/2024 |
0.10508 % | Millennium Management LLC | 1,25,375 | -43,216 | 30/6/2024 |
0.10477 % | Simplify Asset Management Inc | 1,25,000 | 0 | 30/6/2024 |
0.10477 % | MPM BioImpact LLC | 1,25,000 | 1,25,000 | 30/6/2024 |
0.10402 % | BlackRock Asset Management Ireland Limited | 1,24,107 | 52,847 | 30/6/2024 |
0.10298 % | Goldman Sachs Asset Management, L.P. | 1,22,869 | -11,675 | 30/6/2024 |
0.10105 % | Rafferty Asset Management LLC | 1,20,557 | -1,46,575 | 30/6/2024 |
0.10034 % | Aperio Group, LLC | 1,19,720 | 3,647 | 30/6/2024 |
0.09991 % | T. Rowe Price International Ltd | 1,19,205 | -14,520 | 30/6/2024 |
0.09774 % | EAM Global Investors LLC | 1,16,615 | 1,16,615 | 30/6/2024 |
0.09723 % | Medical Strategy GmbH | 1,16,000 | -20,000 | 30/6/2024 |
0.09681 % | Squarepoint Capital LLP | 1,15,508 | 51,743 | 30/6/2024 |
0.09673 % | Raymond James Financial Services Advisors, Inc. | 1,15,403 | 3,370 | 30/9/2024 |
0.09368 % | Marshall Wace LLP | 1,11,770 | 9,906 | 30/6/2024 |
0.09227 % | Mellon Investments Corporation | 1,10,088 | 39,639 | 30/6/2024 |
0.08749 % | UBS Financial Services, Inc. | 1,04,383 | -91,063 | 30/6/2024 |
0.08650 % | Steward Partners Investment Advisory, LLC | 1,03,200 | 2,700 | 30/6/2024 |
0.08508 % | Wells Fargo Advisors | 1,01,512 | -30,375 | 30/6/2024 |
0.08503 % | Avantis Investors | 1,01,454 | 1,01,454 | 31/3/2024 |
0.08339 % | Driehaus Capital Management, LLC | 99,496 | 99,496 | 31/8/2024 |
0.08335 % | DWS Investment GmbH | 99,444 | 0 | 30/6/2024 |
0.08194 % | BlackRock Investment Management (UK) Ltd. | 97,768 | 35,235 | 30/6/2024 |
0.07993 % | Allianz Global Investors GmbH | 95,365 | 0 | 31/8/2024 |
0.07880 % | McCarthy (Teresa) | 94,018 | 0 | 16/10/2024 |
0.07743 % | Legal & General Investment Management Ltd. | 92,379 | 16,330 | 30/6/2024 |
0.07597 % | EAM Investors, LLC | 90,635 | 90,635 | 30/6/2024 |
0.07576 % | Barclays Bank PLC | 90,391 | -32,256 | 30/6/2024 |
0.07123 % | MacLean (Michael F.) | 84,980 | 38,490 | 23/9/2024 |
0.06987 % | Cinctive Capital Management LP | 83,362 | 83,362 | 30/6/2024 |
0.06616 % | California State Teachers Retirement System | 78,937 | 7,363 | 30/6/2024 |
0.06558 % | Hennion & Walsh Asset Management, Inc. | 78,238 | -975 | 30/9/2024 |
0.06407 % | Wilson (Troy Edward) | 76,444 | -5,50,000 | 15/4/2024 |