11,35408 % | Jennison Associates LLC | 5.546.467 | 376.232 | 30/6/2024 |
7,93902 % | T. Rowe Price Investment Management, Inc. | 3.878.210 | 1.407.717 | 30/6/2024 |
6,77555 % | BlackRock Institutional Trust Company, N.A. | 3.309.856 | 553.132 | 30/6/2024 |
6,21626 % | Adage Capital Management, L.P. | 3.036.645 | 0 | 30/6/2024 |
5,65177 % | Bain Capital Life Sciences Investors, LLC | 2.760.888 | 1.110.924 | 12/8/2024 |
5,16455 % | Fred Alger Management, LLC | 2.522.882 | -587.432 | 30/6/2024 |
4,83163 % | The Vanguard Group, Inc. | 2.360.250 | 89.835 | 30/6/2024 |
4,53767 % | Alkeon Capital Management LLC | 2.216.650 | 1.799.640 | 30/6/2024 |
3,20154 % | VR Adviser, LLC | 1.563.952 | 0 | 30/6/2024 |
2,76250 % | Nichtberger (Steven) | 1.349.483 | 0 | 4/4/2024 |
2,56602 % | Polar Capital LLP | 1.253.500 | 3.500 | 30/6/2024 |
2,49826 % | Sofinnova Investments, Inc | 1.220.400 | 790.654 | 30/6/2024 |
2,43650 % | BlackRock Financial Management, Inc. | 1.190.229 | 109.677 | 30/6/2024 |
2,41168 % | StemPoint Capital LP | 1.178.105 | 174.189 | 30/6/2024 |
2,25179 % | Commodore Capital LP | 1.100.000 | 0 | 30/6/2024 |
1,98684 % | Geode Capital Management, L.L.C. | 970.573 | 197.483 | 30/6/2024 |
1,83444 % | State Street Global Advisors (US) | 896.123 | -1.109.678 | 30/9/2024 |
1,42951 % | Millennium Management LLC | 698.317 | 238.950 | 30/6/2024 |
1,29829 % | Victory Capital Management Inc. | 634.217 | 262.594 | 30/6/2024 |
1,29214 % | JP Morgan Asset Management | 631.211 | 630.368 | 30/6/2024 |
1,19764 % | Perceptive Advisors LLC | 585.045 | -1.131.615 | 30/6/2024 |
1,14866 % | T. Rowe Price Associates, Inc. | 561.120 | -34.064 | 30/6/2024 |
1,00738 % | Lynx1 Capital Advisors LLC | 492.103 | -1.590.870 | 30/6/2024 |
0,95791 % | Two Sigma Investments, LP | 467.937 | 431.263 | 30/6/2024 |
0,95036 % | Deerfield Management Company, L.P. | 464.252 | -794.398 | 30/6/2024 |
0,90650 % | Redmile Group, LLC | 442.826 | 0 | 30/6/2024 |
0,87001 % | Integral Health Asset Management, LLC | 425.000 | 0 | 30/6/2024 |
0,82160 % | Oppenheimer Asset Management Inc. | 401.350 | 318.360 | 30/6/2024 |
0,76604 % | Goldman Sachs & Company, Inc. | 374.210 | -15.066 | 30/6/2024 |
0,75926 % | Ghost Tree Capital, LLC | 370.899 | -4.101 | 30/6/2024 |
0,67592 % | Marshall Wace LLP | 330.187 | 159.000 | 30/6/2024 |
0,67021 % | Artisan Partners Limited Partnership | 327.397 | -7.416 | 30/6/2024 |
0,65414 % | Citadel Advisors LLC | 319.546 | 317.305 | 30/6/2024 |
0,64561 % | Squarepoint Capital LLP | 315.379 | 272.948 | 30/6/2024 |
0,62409 % | UBS Asset Management (Americas), Inc. | 304.870 | 278.080 | 30/6/2024 |
0,62093 % | Qube Research & Technologies Ltd | 303.326 | -131.174 | 30/6/2024 |
0,61453 % | Exome Asset Management LLC | 300.200 | 300.200 | 30/6/2024 |
0,61372 % | PanAgora Asset Management Inc. | 299.801 | 299.801 | 30/6/2024 |
0,60720 % | Jane Street Capital, L.L.C. | 296.615 | 245.896 | 30/6/2024 |
0,58633 % | E Fund Management Co. Ltd. | 286.424 | 269.675 | 30/6/2024 |
0,58245 % | Northern Trust Investments, Inc. | 284.529 | 3.009 | 30/6/2024 |
0,58137 % | PGIM Securities Investment Trust Enterprise | 284.000 | -199.265 | 30/6/2024 |
0,55431 % | AXA Investment Managers UK Ltd. | 270.778 | 92.616 | 30/6/2024 |
0,53588 % | JPMorgan Asset Management U.K. Limited | 261.777 | -28.603 | 30/6/2024 |
0,49740 % | Woodline Partners LP | 242.981 | 318 | 30/6/2024 |
0,45019 % | Weatherbie Capital, LLC | 219.916 | 53.307 | 31/8/2024 |
0,39721 % | Schonfeld Strategic Advisors LLC | 194.037 | -123.483 | 30/6/2024 |
0,38886 % | Walleye Capital LLC | 189.957 | 189.957 | 30/6/2024 |
0,37285 % | Jump Financial, LLC | 182.135 | 182.135 | 30/6/2024 |
0,35955 % | Morgan Stanley Smith Barney LLC | 175.640 | 44.145 | 30/6/2024 |
0,34827 % | Westwood Management Corp. (Texas) | 170.129 | 87.901 | 30/6/2024 |
0,34617 % | BofA Global Research (US) | 169.105 | -20.875 | 30/6/2024 |
0,32753 % | Raiffeisen Kapitalanlage-Gesellschaft mbH | 160.000 | 0 | 31/8/2024 |
0,32510 % | Wellington Management Company, LLP | 158.809 | -849.450 | 30/6/2024 |
0,30731 % | Nuveen LLC | 150.123 | -46.104 | 30/6/2024 |
0,30359 % | BlackRock Investment Management, LLC | 148.305 | 40.490 | 30/6/2024 |
0,29303 % | Simon (Mark) | 143.144 | 0 | 4/4/2024 |
0,28638 % | Superstring Capital Management LP | 139.895 | -150.902 | 30/6/2024 |
0,27437 % | TD Asset Management Inc. | 134.030 | 7.000 | 30/6/2024 |
0,26264 % | MFS Investment Management | 128.298 | 0 | 31/8/2024 |
0,24223 % | Charles Schwab Investment Management, Inc. | 118.327 | 24.802 | 30/6/2024 |
0,23916 % | Morgan Stanley & Co. LLC | 116.832 | -617.325 | 30/6/2024 |
0,22518 % | Medical Strategy GmbH | 110.000 | -15.000 | 30/6/2024 |
0,22467 % | BNY Mellon Asset Management | 109.751 | 23.972 | 30/6/2024 |
0,21434 % | Crestline Investors, Inc. | 104.705 | 19.705 | 30/6/2024 |
0,21204 % | Rafferty Asset Management LLC | 103.582 | -250.842 | 30/6/2024 |
0,19488 % | Prelude Capital Management, LLC | 95.200 | 95.200 | 30/6/2024 |
0,18154 % | BlackRock Asset Management Ireland Limited | 88.683 | 12.090 | 30/6/2024 |
0,17768 % | TCG Crossover Management, LLC | 86.795 | 0 | 30/6/2024 |
0,15663 % | Voloridge Investment Management, LLC | 76.513 | -201.610 | 30/6/2024 |
0,14330 % | LifeSci Fund Management LLC | 70.000 | 5.000 | 30/6/2024 |
0,14037 % | UBS Financial Services, Inc. | 68.573 | -140.903 | 30/6/2024 |
0,13710 % | Susquehanna International Group, LLP | 66.973 | 2.874 | 30/6/2024 |
0,13613 % | Schweizerische Nationalbank | 66.500 | 7.300 | 30/6/2024 |
0,13230 % | AllianceBernstein L.P. | 64.630 | 33.320 | 30/6/2024 |
0,13167 % | Healthinvest Partners AB | 64.321 | -13.219 | 30/6/2024 |
0,12864 % | RBC Capital Markets Wealth Management | 62.841 | -13.347 | 30/6/2024 |
0,12667 % | Rhumbline Advisers Ltd. Partnership | 61.880 | 16.274 | 30/6/2024 |
0,11797 % | Verition Fund Management LLC | 57.626 | 57.626 | 30/6/2024 |
0,11641 % | JPMorgan Private Bank (United States) | 56.867 | 43.365 | 30/6/2024 |
0,11633 % | Balyasny Asset Management LP | 56.828 | 41.865 | 30/6/2024 |
0,11550 % | Manulife Investment Management (North America) Limited | 56.424 | 4.191 | 30/6/2024 |
0,10215 % | UBS Asset Management (Switzerland) | 49.902 | 36.981 | 30/6/2024 |
0,10146 % | SEB Investment Management AB | 49.563 | 0 | 30/6/2024 |
0,09652 % | Nan Fung Life Sciences | 47.150 | 0 | 30/6/2024 |
0,08442 % | Barclays Bank PLC | 41.239 | -7.729 | 30/6/2024 |
0,08304 % | Mellon Investments Corporation | 40.566 | 20.184 | 30/6/2024 |
0,08168 % | Newton Investment Management North America, LLC | 39.900 | 0 | 30/6/2024 |
0,07185 % | SG Americas Securities, L.L.C. | 35.098 | 35.098 | 30/9/2024 |
0,06924 % | California State Teachers Retirement System | 33.825 | 3.397 | 30/6/2024 |
0,06868 % | Osaic Holdings, Inc. | 33.548 | 121 | 30/6/2024 |
0,06564 % | UBS Fund Management (Switzerland) AG | 32.064 | -1.324 | 30/6/2024 |
0,06537 % | Corton Capital Inc | 31.931 | 31.931 | 30/6/2024 |
0,06366 % | Aquatic Capital Management LLC | 31.100 | 31.100 | 30/6/2024 |
0,06147 % | Envestnet Asset Management, Inc. | 30.026 | -2.538 | 30/6/2024 |
0,06027 % | LPL Financial LLC | 29.441 | -5.492 | 30/6/2024 |
0,05842 % | Legal & General Investment Management Ltd. | 28.540 | 5.122 | 30/6/2024 |
0,05780 % | Trexquant Investment LP | 28.233 | -41.184 | 30/6/2024 |
0,05673 % | MetLife Investment Management, LLC | 27.714 | 9.399 | 30/6/2024 |
0,05635 % | BlackRock Advisors (UK) Limited | 27.527 | 609 | 30/9/2024 |