7,05 % | Commodore Capital LP | 4.747.373 | 319.301 | 31/12/2023 |
5,94 % | Incyte Corp | 4.004.544 | 0 | 25/3/2024 |
5,07 % | Samlyn Capital, LLC | 3.412.410 | 155.892 | 31/12/2023 |
4,48 % | Deerfield Management Company, L.P. | 3.019.901 | -857.037 | 31/12/2023 |
4,09 % | BVF Partners L.P. | 2.752.420 | 0 | 31/12/2023 |
3,52 % | RTW Investments L.P. | 2.373.625 | 376.861 | 31/12/2023 |
3,41 % | Federated Hermes Global Investment Management Corp. | 2.297.700 | -1.339.609 | 29/2/2024 |
3,19 % | VR Adviser, LLC | 2.148.214 | 422.000 | 31/12/2023 |
2,98 % | Wellington Management Company, LLP | 2.009.403 | -725.844 | 31/12/2023 |
2,82 % | Boxer Capital, L.L.C. | 1.900.000 | 0 | 31/12/2023 |
2,78 % | Franklin Advisers, Inc. | 1.875.391 | -9.135 | 31/12/2023 |
1,95 % | Driehaus Capital Management, LLC | 1.311.013 | 175.818 | 31/12/2023 |
1,83 % | Balyasny Asset Management LP | 1.233.238 | 372.879 | 31/12/2023 |
1,83 % | Pictet Asset Management Ltd. | 1.232.808 | 268.961 | 31/12/2023 |
1,74 % | Medicxi Ventures (UK) LLP | 1.169.028 | -430.972 | 31/3/2024 |
1,69 % | Lynx1 Capital Advisors LLC | 1.135.225 | -15.000 | 31/12/2023 |
1,32 % | Avoro Capital Advisors LLC | 888.888 | 444.444 | 31/12/2023 |
1,29 % | Rock Springs Capital Management LP | 872.069 | 33.641 | 31/12/2023 |
1,17 % | BlackRock Financial Management, Inc. | 789.986 | 242 | 31/12/2023 |
1,11 % | Two Sigma Investments, LP | 746.553 | 469.263 | 31/12/2023 |
1,11 % | Frazier Healthcare Partners | 746.479 | 0 | 31/12/2023 |
1,08 % | Fidelity Management & Research Company LLC | 730.453 | -44.500 | 31/12/2023 |
1,06 % | Fairmount Funds Management LLC | 717.254 | -1.164.091 | 31/12/2023 |
1,03 % | Millennium Management LLC | 693.327 | 64.128 | 31/12/2023 |
0,96 % | SilverArc Capital Management, LLC | 645.581 | 145.581 | 31/12/2023 |
0,79 % | Janus Henderson Investors | 531.044 | 332.756 | 31/12/2023 |
0,77 % | 5AM Ventures | 521.531 | 521.531 | 31/12/2023 |
0,74 % | StemPoint Capital LP | 501.806 | 501.806 | 31/12/2023 |
0,71 % | Candriam Luxembourg S.A. | 480.227 | 0 | 29/2/2024 |
0,68 % | Dafna Capital Management, LLC | 454.870 | -30.000 | 31/12/2023 |
0,60 % | Carmignac Gestion | 403.861 | -50.470 | 31/12/2023 |
0,58 % | Saturn V Capital Management LLC | 389.333 | 349.267 | 31/12/2023 |
0,58 % | BlackRock Institutional Trust Company, N.A. | 388.708 | -33.448 | 31/12/2023 |
0,56 % | Goldman Sachs & Company, Inc. | 378.477 | 172.500 | 31/12/2023 |
0,55 % | Braidwell LP | 370.679 | -1.530.658 | 31/12/2023 |
0,53 % | Aquilo Capital Management, LLC | 355.109 | -75.000 | 31/12/2023 |
0,49 % | Medical Strategy GmbH | 331.487 | 0 | 31/12/2023 |
0,49 % | Adage Capital Management, L.P. | 330.000 | 230.000 | 31/12/2023 |
0,45 % | Soleus Capital Management, L.P. | 302.577 | -81.913 | 31/12/2023 |
0,45 % | Morgan Stanley & Co. LLC | 302.531 | 113.386 | 31/12/2023 |
0,42 % | Citadel Advisors LLC | 280.251 | 277.066 | 31/12/2023 |
0,41 % | Ally Bridge Group NY LLC | 274.923 | 53.539 | 31/12/2023 |
0,38 % | Candriam Belgium S.A. | 257.419 | -605.657 | 30/11/2023 |
0,36 % | Woodline Partners LP | 243.229 | 0 | 31/12/2023 |
0,35 % | State Street Global Advisors (US) | 235.688 | 15.910 | 31/12/2023 |
0,34 % | Sphera Funds Management Ltd. | 230.333 | -23.000 | 31/12/2023 |
0,31 % | BlackRock Advisors (UK) Limited | 207.715 | -129 | 31/3/2024 |
0,28 % | BlackRock Asset Management Ireland Limited | 187.172 | 2.031 | 31/12/2023 |
0,28 % | T. Rowe Price Investment Management, Inc. | 186.300 | 186.300 | 31/3/2024 |
0,25 % | AllianceBernstein L.P. | 169.098 | -23.186 | 31/12/2023 |
0,23 % | Parkman Healthcare Partners LLC | 157.817 | 27.082 | 31/12/2023 |
0,23 % | Liu (Hui) | 156.016 | 98.085 | 15/3/2024 |
0,23 % | Lundberg (Sven Ante) | 152.071 | 0 | 15/3/2024 |
0,21 % | The Vanguard Group, Inc. | 142.833 | -27.093 | 31/12/2023 |
0,21 % | Platinum Asset Management | 142.029 | 0 | 31/12/2023 |
0,20 % | Nan Fung Life Sciences | 137.038 | 0 | 31/12/2023 |
0,20 % | HighVista Strategies LLC | 133.572 | 10.941 | 31/12/2023 |
0,19 % | Cubist Systematic Strategies, LLC | 126.505 | 126.505 | 31/12/2023 |
0,18 % | UBS O'Connor LLC | 121.300 | -30.806 | 31/12/2023 |
0,17 % | Eversept Partners, LP | 115.726 | -18.284 | 31/12/2023 |
0,16 % | DWS Investment GmbH | 110.000 | 0 | 31/12/2023 |
0,15 % | Morgan Stanley Investment Management Inc. (US) | 99.934 | -51.326 | 31/12/2023 |
0,14 % | Allianz Global Investors U.S. LLC_NLE | 93.975 | 0 | 30/9/2023 |
0,14 % | Voya Investment Management LLC | 93.975 | 0 | 31/12/2023 |
0,13 % | Wellington Management Japan Pte Ltd | 89.295 | -61.818 | 30/6/2023 |
0,13 % | Hudson Bay Capital Management LP | 87.200 | -80.618 | 31/12/2023 |
0,13 % | Nomura Asset Management Co., Ltd. | 87.000 | 87.000 | 30/11/2023 |
0,11 % | Iwicki (Mark T.) | 73.576 | 73.576 | 15/3/2024 |
0,11 % | Schweizerische Nationalbank | 72.654 | -20.700 | 31/12/2023 |
0,10 % | Algert Global LLC | 68.933 | -1.549 | 31/12/2023 |
0,09 % | BNP Paribas Securities Corp. North America | 62.825 | 36.160 | 31/12/2023 |
0,09 % | Norges Bank Investment Management (NBIM) | 60.300 | -14.700 | 31/12/2023 |
0,09 % | D. E. Shaw & Co., L.P. | 59.033 | 59.033 | 31/12/2023 |
0,08 % | Deka Vermögensmanagement GmbH | 56.000 | 31.000 | 31/12/2023 |
0,08 % | HBM Partners AG | 56.000 | 5.000 | 30/9/2023 |
0,08 % | Geode Capital Management, L.L.C. | 53.608 | 150 | 31/12/2023 |
0,07 % | Campbell & Company, Inc. | 48.007 | 48.007 | 31/12/2023 |
0,07 % | MFS Investment Management | 47.926 | -1.447 | 29/2/2024 |
0,07 % | Invesco Capital Management LLC | 46.208 | 46.208 | 31/12/2023 |
0,07 % | Jump Financial, LLC | 46.120 | 46.120 | 31/12/2023 |
0,07 % | Credit Suisse Funds AG | 44.990 | -3.675 | 31/12/2023 |
0,06 % | Nuveen LLC | 43.677 | -14.214 | 31/12/2023 |
0,06 % | Trexquant Investment LP | 40.489 | 23.503 | 31/12/2023 |
0,06 % | Alps Advisors, Inc. | 40.128 | 40.128 | 31/12/2023 |
0,06 % | ExodusPoint Capital Management, LP | 39.087 | 39.087 | 31/12/2023 |
0,06 % | T. Rowe Price Associates, Inc. | 39.064 | 9.569 | 29/2/2024 |
0,06 % | Assenagon Asset Management S.A. | 38.383 | 2.820 | 29/2/2024 |
0,06 % | Northern Trust Investments, Inc. | 38.022 | 952 | 31/12/2023 |
0,06 % | HRT Financial LP | 37.773 | 11.265 | 31/12/2023 |
0,06 % | Schonfeld Strategic Advisors LLC | 37.600 | -201.770 | 31/12/2023 |
0,06 % | UBS Asset Management (Americas), Inc. | 37.426 | -1.093 | 31/3/2023 |
0,05 % | Atom Investors LP | 35.544 | 21.976 | 31/12/2023 |
0,05 % | First Trust Advisors L.P. | 35.185 | 1.247 | 31/12/2023 |
0,05 % | Legal & General Investment Management Ltd. | 34.621 | -1.848 | 31/12/2023 |
0,05 % | California State Teachers Retirement System | 32.809 | -4.759 | 31/12/2023 |
0,04 % | State of Wisconsin Investment Board | 25.618 | -1.737 | 31/12/2023 |
0,04 % | Deka Investment GmbH | 25.000 | 20.600 | 31/12/2022 |
0,04 % | Sanders Morris LLC | 24.870 | 0 | 31/3/2024 |
0,04 % | Susquehanna Portfolio Strategies, LLC | 24.628 | 24.628 | 31/12/2023 |
0,04 % | Tudor Investment Corporation | 24.443 | 805 | 31/12/2023 |