16,81894 % | Cormorant Asset Management, LP | 2.025.000 | 0 | 30/6/2024 |
9,26080 % | Octagon Capital Advisors LP | 1.115.000 | 627.000 | 30/9/2024 |
5,86161 % | BlackRock Institutional Trust Company, N.A. | 705.738 | 489.032 | 30/6/2024 |
4,85871 % | The Vanguard Group, Inc. | 584.989 | 147.725 | 30/6/2024 |
3,67386 % | State Street Global Advisors (US) | 442.333 | 406.354 | 30/6/2024 |
3,57294 % | RA Capital Management, LP | 430.182 | 430.182 | 2/2/2024 |
3,54003 % | Tang Capital Management, LLC | 426.220 | 426.220 | 26/1/2024 |
3,32226 % | Adage Capital Management, L.P. | 400.000 | -15.000 | 30/6/2024 |
3,31942 % | Paradigm BioCapital Advisors LP | 399.658 | 399.658 | 26/1/2024 |
2,76380 % | Citadel Advisors LLC | 332.761 | -36.406 | 30/6/2024 |
2,70050 % | Darwin Global Management Ltd | 325.140 | 325.140 | 30/6/2024 |
2,57093 % | Ikarian Capital LLC | 309.540 | -249.731 | 30/6/2024 |
2,45241 % | T. Rowe Price Associates, Inc. | 295.270 | 102.775 | 30/6/2024 |
2,13882 % | Morgan Stanley & Co. LLC | 257.514 | 85.849 | 30/6/2024 |
2,07026 % | Woodline Partners LP | 249.259 | 208.278 | 30/6/2024 |
1,91908 % | Geode Capital Management, L.L.C. | 231.057 | 122.249 | 30/6/2024 |
1,87014 % | Sio Capital Management, LLC | 225.165 | 225.165 | 30/6/2024 |
1,83708 % | Assenagon Asset Management S.A. | 221.184 | -17.575 | 30/9/2024 |
1,79830 % | Point72 Asset Management, L.P. | 216.515 | -485.082 | 30/6/2024 |
1,79070 % | Avidity Partners Management LP | 215.600 | 215.600 | 30/6/2024 |
1,68831 % | Janus Henderson Investors | 203.272 | -135.802 | 30/6/2024 |
1,54273 % | K2 HealthVentures LLC | 185.745 | 185.745 | 31/12/2023 |
1,45349 % | Ghost Tree Capital, LLC | 175.000 | 118.059 | 30/6/2024 |
1,43266 % | SilverArc Capital Management, LLC | 172.492 | 140.512 | 30/6/2024 |
1,38533 % | Vivo Capital, LLC | 166.794 | 166.794 | 30/6/2024 |
1,37602 % | Global X Investments Canada Inc. | 165.673 | 137.515 | 30/9/2024 |
1,24909 % | Walleye Capital LLC | 150.391 | 17.807 | 30/6/2024 |
1,16528 % | Schonfeld Strategic Advisors LLC | 140.300 | 16.027 | 30/6/2024 |
1,01953 % | Millennium Management LLC | 122.751 | -118.898 | 30/9/2024 |
0,96571 % | ExodusPoint Capital Management, LP | 116.271 | 116.271 | 30/6/2024 |
0,84285 % | StemPoint Capital LP | 101.479 | 101.479 | 30/6/2024 |
0,83056 % | Integral Health Asset Management, LLC | 100.000 | 100.000 | 30/6/2024 |
0,76186 % | Barclays Bank PLC | 91.728 | -93.420 | 30/6/2024 |
0,71718 % | Boothbay Fund Management, LLC | 86.349 | -69.664 | 30/6/2024 |
0,70424 % | Exome Asset Management LLC | 84.790 | -3.056 | 30/6/2024 |
0,60500 % | Verition Fund Management LLC | 72.842 | 72.842 | 30/6/2024 |
0,53574 % | Schroder Investment Management Ltd. (SIM) | 64.503 | 0 | 30/6/2024 |
0,53571 % | Acuta Capital Partners, LLC | 64.500 | 64.500 | 30/6/2024 |
0,52375 % | Driehaus Capital Management, LLC | 63.059 | 0 | 30/6/2024 |
0,50272 % | Goldman Sachs & Company, Inc. | 60.528 | -45.850 | 30/6/2024 |
0,46900 % | Superstring Capital Management LP | 56.468 | 56.468 | 30/6/2024 |
0,44092 % | BofA Global Research (US) | 53.087 | 25.092 | 30/6/2024 |
0,42590 % | Wellington Management Company, LLP | 51.278 | 51.278 | 30/6/2024 |
0,41528 % | Smethurst (Dominic) | 50.000 | 50.000 | 27/2/2024 |
0,40708 % | Cinctive Capital Management LP | 49.013 | 49.013 | 30/6/2024 |
0,37678 % | Ensign Peak Advisors, Inc. | 45.364 | -22.136 | 30/6/2024 |
0,36674 % | Wexford Capital LP | 44.156 | 44.156 | 30/6/2024 |
0,35714 % | Hudson Bay Capital Management LP | 43.000 | 0 | 30/6/2024 |
0,33887 % | TD Asset Management Inc. | 40.800 | 19.600 | 30/6/2024 |
0,32475 % | Healthinvest Partners AB | 39.100 | 1.100 | 30/6/2024 |
0,32220 % | HighVista Strategies LLC | 38.793 | 38.793 | 30/6/2024 |
0,30278 % | NEOS Investment Management, LLC | 36.455 | 36.455 | 30/6/2024 |
0,27545 % | Trexquant Investment LP | 33.164 | 21.180 | 30/6/2024 |
0,25020 % | Mirae Asset Global Investments (USA) LLC | 30.124 | 5.244 | 30/6/2024 |
0,23956 % | Charles Schwab Investment Management, Inc. | 28.843 | 24.030 | 30/6/2024 |
0,23904 % | BlackRock Investment Management, LLC | 28.780 | 27.038 | 30/6/2024 |
0,23171 % | Nuveen LLC | 27.898 | 27.898 | 30/6/2024 |
0,22337 % | abrdn Inc. | 26.894 | 21.751 | 30/9/2024 |
0,22222 % | BlackRock Financial Management, Inc. | 26.755 | 25.521 | 30/6/2024 |
0,21400 % | Northern Trust Investments, Inc. | 25.765 | 5.764 | 30/6/2024 |
0,19279 % | Rafferty Asset Management LLC | 23.212 | 23.212 | 30/6/2024 |
0,18475 % | BNY Mellon Asset Management | 22.244 | 22.244 | 30/6/2024 |
0,17981 % | UBS Financial Services, Inc. | 21.649 | 6.184 | 30/6/2024 |
0,17551 % | Manulife Investment Management (North America) Limited | 21.131 | 10.604 | 30/6/2024 |
0,17110 % | Zimmer Partners, LP | 20.600 | 20.600 | 30/6/2024 |
0,16611 % | Artia Global Partners LP | 20.000 | 20.000 | 30/6/2024 |
0,15831 % | Victory Capital Management Inc. | 19.060 | 19.060 | 30/6/2024 |
0,14079 % | Florida State Board of Administration | 16.951 | 16.951 | 30/6/2024 |
0,13351 % | Dimensional Fund Advisors, L.P. | 16.075 | 0 | 30/6/2024 |
0,13306 % | ClariVest Asset Management LLC | 16.021 | 16.021 | 30/6/2024 |
0,13168 % | Acadian Asset Management LLC | 15.854 | 15.854 | 30/6/2024 |
0,12458 % | Jefferies LLC | 15.000 | 3.900 | 30/6/2024 |
0,11998 % | Prelude Capital Management, LLC | 14.446 | -3.500 | 30/6/2024 |
0,11713 % | Rhumbline Advisers Ltd. Partnership | 14.103 | 14.103 | 30/6/2024 |
0,10473 % | EAM Investors, LLC | 12.609 | 12.609 | 30/6/2024 |
0,10193 % | Jump Financial, LLC | 12.272 | 12.272 | 30/6/2024 |
0,09967 % | Adar1 Capital Management LLC | 12.000 | -4.000 | 30/6/2024 |
0,09480 % | Columbia Threadneedle Investments (US) | 11.414 | 11.414 | 30/6/2024 |
0,09409 % | Gilder Gagnon Howe & Co. LLC | 11.328 | 11.328 | 30/6/2024 |
0,08548 % | Jane Street Capital, L.L.C. | 10.292 | -22.108 | 30/6/2024 |
0,07757 % | MFS Investment Management | 9.340 | 1.190 | 31/8/2024 |
0,07001 % | Moran (Sean F) | 8.429 | 0 | 18/6/2024 |
0,06638 % | Mellon Investments Corporation | 7.992 | 7.992 | 30/6/2024 |
0,06264 % | Fidelity Management & Research Company LLC | 7.542 | -1.612 | 30/6/2024 |
0,06089 % | SG Americas Securities, L.L.C. | 7.331 | 7.331 | 30/9/2024 |
0,05988 % | AllianceBernstein L.P. | 7.210 | 7.210 | 30/6/2024 |
0,05744 % | T. Rowe Price International Ltd | 6.916 | 4.252 | 30/6/2024 |
0,05455 % | GWM Advisors LLC | 6.568 | 6.560 | 30/6/2024 |
0,04849 % | Susquehanna International Group, LLP | 5.838 | 5.838 | 30/6/2024 |
0,04841 % | Holmer (Alan F) | 5.829 | 1.667 | 14/6/2024 |
0,04623 % | Kung (Winston) | 5.566 | 5.566 | 16/8/2024 |
0,04541 % | Corebridge Financial Inc | 5.467 | 5.467 | 30/6/2024 |
0,04541 % | SunAmerica Asset Management, LLC | 5.467 | 0 | 31/7/2024 |
0,04058 % | Goldman Sachs Asset Management, L.P. | 4.886 | 1.641 | 30/9/2024 |
0,03817 % | Invesco Advisers, Inc. | 4.596 | 4.596 | 30/6/2024 |
0,03640 % | Citi Investment Research (US) | 4.383 | -10.924 | 30/6/2024 |
0,03613 % | Catlin (Avery W) | 4.350 | 2.783 | 30/5/2024 |
0,03597 % | JPMorgan Private Bank (United States) | 4.331 | 4.331 | 30/6/2024 |
0,03405 % | New York State Common Retirement Fund | 4.100 | 0 | 30/9/2024 |
0,03341 % | DWS Investments UK Limited | 4.022 | 4.022 | 30/6/2024 |