Upstream Bio Rule of 40
The Rule of 40 of Upstream Bio (UPB) as of Oct 10, 2026 is -5,598.39 %. In the previous year, Rule of 40 was -3,281.60 % — a change of 70.60% (lower).
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Rule of 40
-5,598.39 %
YoY
70.60%
Last updated:
Rule of 40 of Upstream Bio is 2025 -5,598.39 % . Rule of 40 of Upstream Bio was 2024 -3,281.60 % . It decreases by 70.60% lower compared to the previous year.
The Upstream Bio Rule of 40 history
3 Years
10 Years
25 Years
Max
Rule of 40
Date
Rule of 40
Jan 1, 2023
-1,589.09 USD
Jan 1, 2024
-3,281.60 USD
Jan 1, 2025
-5,598.39 USD
| YEAR | Rule of 40 | YoY |
|---|---|---|
| -5,598.39 % | +70.60% | |
| -3,281.60 % | +106.51% | |
| -1,589.09 % | — |
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Upstream Bio Stock analysis
What does Upstream Bio do? Upstream Bio is one of the most popular companies on Eulerpool.
Frequently Asked Questions about Upstream Bio stock
Rule of 40 of Upstream Bio is -5,598.39 % in 2025.
On Eulerpool you can find the complete historical development of Rule of 40 Upstream Bio since 2006 – with annual values, charts, and detailed analysis.
The Rule of 40 states that a company's revenue growth rate plus profit margin should exceed 40%. It is widely used to evaluate SaaS and high-growth companies.
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Quality — Upstream Bio
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