Clene

Clene Rule of 40

The Rule of 40 of Clene (CLNN) as of Oct 15, 2026 is -11,787.02 %. In the previous year, Rule of 40 was -10,410.28 % — a change of 13.22% (lower).

Rule of 40

-11,787.02 %

YoY

13.22%

Last updated:

Rule of 40 of Clene is 2025 -11,787.02 % . Rule of 40 of Clene was 2024 -10,410.28 % . It decreases by 13.22% lower compared to the previous year.

The Clene Rule of 40 history

  • 3 Years

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  • 25 Years

  • Max

Rule of 40
Date
Rule of 40
Jan 1, 2021
-6,661.62 USD
Jan 1, 2022
-10,269.04 USD
Jan 1, 2023
-6,834.21 USD
Jan 1, 2024
-10,410.28 USD
Jan 1, 2025
-11,787.02 USD
The Clene Rule of 40 history
YEARRule of 40YoY
-11,787.02 %+13.22%
-10,410.28 %+52.33%
-6,834.21 %-33.45%
-10,269.04 %+54.15%
-6,661.62 %—

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Clene Stock analysis

What does Clene do? Clene Inc is a clinical-stage biopharmaceutical company based in Salt Lake City, Utah, operating within the health care sector and specifically in the biotechnology industry. The company went public via an IPO on August 27, 2018, and currently employs 75 full-time staff. Clene focuses on developing therapeutics for neurodegenerative diseases, with its primary drug candidate being CNM-Au8, an oral suspension of gold nanocrystals. The company's research targets energetic failure, an underlying factor in many neurological conditions, aiming to restore neuronal health and function by enhancing energy production and utilization. CNM-Au8 works through catalytically active nanocrystals that support cellular energy processes, promoting neuroprotection and remyelination by improving resilience to disease-related stressors. The company also has other product candidates, including CNM-ZnAg, a spectrum antiviral and antibacterial agent composed of zinc and silver ions, and CNM-AgZn17, a gel polymer suspension of zinc and silver designed for treating infectious diseases and supporting wound healing. Clene's website is https://clene.com/ and it is listed under the ticker CLNN with ISIN US1856342019. The company remains in the clinical development phase, focusing on advancing its pipeline of treatments for neurological and infectious conditions. Clene is one of the most popular companies on Eulerpool.

Frequently Asked Questions about Clene stock

Rule of 40 of Clene is -11,787.02 % in 2025.

On Eulerpool you can find the complete historical development of Rule of 40 Clene since 2006 – with annual values, charts, and detailed analysis.

The Rule of 40 states that a company's revenue growth rate plus profit margin should exceed 40%. It is widely used to evaluate SaaS and high-growth companies.

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Quality — Clene

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