14,70336 % | Baker Bros. Advisors LP | 10.045.336 | 500.000 | 30.6.2024 |
13,23925 % | T. Rowe Price Associates, Inc. | 9.045.056 | 2.654.481 | 30.6.2024 |
8,14124 % | Redmile Group, LLC | 5.562.096 | 1.832.113 | 30.6.2024 |
7,12302 % | Forbion Capital Partners | 4.866.449 | 0 | 30.6.2024 |
5,81871 % | BlackRock Institutional Trust Company, N.A. | 3.975.343 | 31.568 | 30.6.2024 |
4,56387 % | Millennium Management LLC | 3.118.035 | 2.656.173 | 30.6.2024 |
4,22540 % | The Vanguard Group, Inc. | 2.886.794 | 124.786 | 30.6.2024 |
3,60263 % | Omega Fund Management, LLC | 2.461.319 | -540.000 | 30.6.2024 |
3,07128 % | Atlas Venture | 2.098.300 | 0 | 30.6.2024 |
2,56993 % | Coffin (Robert) | 1.755.779 | 17.806 | 30.6.2024 |
2,24874 % | Boxer Capital, L.L.C. | 1.536.341 | 1.536.341 | 30.6.2024 |
2,03486 % | Morgan Stanley & Co. LLC | 1.390.214 | -641.123 | 30.6.2024 |
1,97600 % | Camber Capital Management LP | 1.350.000 | -1.400.000 | 30.6.2024 |
1,86537 % | Astley-Sparke (Philip) | 1.274.421 | -50.000 | 30.8.2024 |
1,77253 % | Geode Capital Management, L.L.C. | 1.210.993 | 19.200 | 30.6.2024 |
1,69476 % | State Street Global Advisors (US) | 1.157.861 | -5.328.835 | 30.6.2024 |
1,65952 % | RTW Investments L.P. | 1.133.787 | 1.133.787 | 30.6.2024 |
1,48328 % | Braidwell LP | 1.013.377 | 1.013.377 | 30.6.2024 |
1,46370 % | Jefferies LLC | 1.000.000 | 0 | 30.6.2024 |
1,43623 % | Schonfeld Strategic Advisors LLC | 981.235 | 822.944 | 30.6.2024 |
1,36385 % | D. E. Shaw & Co., L.P. | 931.780 | -66.006 | 30.6.2024 |
1,24464 % | EcoR1 Capital, LLC | 850.341 | 850.341 | 30.6.2024 |
1,17892 % | Tang Capital Management, LLC | 805.440 | 805.440 | 30.6.2024 |
1,13780 % | Love (Colin) | 777.345 | -17.615 | 16.5.2024 |
1,09366 % | Fidelity Management & Research Company LLC | 747.188 | 460.837 | 30.6.2024 |
0,89385 % | Dimensional Fund Advisors, L.P. | 610.681 | -367.171 | 30.6.2024 |
0,84434 % | Goldman Sachs & Company, Inc. | 576.850 | 151.802 | 30.6.2024 |
0,78502 % | Jane Street Capital, L.L.C. | 536.326 | 378.508 | 30.6.2024 |
0,76844 % | Parkman Healthcare Partners LLC | 525.000 | 525.000 | 30.6.2024 |
0,67316 % | Norges Bank Investment Management (NBIM) | 459.900 | 318.200 | 30.6.2024 |
0,65867 % | Ghost Tree Capital, LLC | 450.000 | -200.000 | 30.6.2024 |
0,63276 % | Charles Schwab Investment Management, Inc. | 432.299 | 13.635 | 30.6.2024 |
0,60995 % | Two Sigma Investments, LP | 416.720 | -114.721 | 30.6.2024 |
0,60085 % | BlackRock Financial Management, Inc. | 410.500 | 54.699 | 30.6.2024 |
0,60076 % | Northern Trust Investments, Inc. | 410.437 | -20.051 | 30.6.2024 |
0,59355 % | Wellington Management Company, LLP | 405.516 | 95.737 | 30.6.2024 |
0,56909 % | DWS Investment GmbH | 388.800 | 5.300 | 30.6.2024 |
0,42977 % | Woodline Partners LP | 293.622 | 0 | 30.6.2024 |
0,38520 % | Esposito (Pamela) | 263.166 | 0 | 12.9.2023 |
0,36584 % | TD Asset Management Inc. | 249.940 | 11.094 | 30.6.2024 |
0,33774 % | Nuveen LLC | 230.745 | 114.980 | 30.6.2024 |
0,31453 % | Citadel Advisors LLC | 214.886 | 147.446 | 30.6.2024 |
0,30216 % | UBS O'Connor LLC | 206.436 | 113.445 | 30.6.2024 |
0,29997 % | Nan Fung Life Sciences | 204.939 | 0 | 30.6.2024 |
0,28866 % | JP Morgan Asset Management | 197.211 | -24.959 | 30.6.2024 |
0,28711 % | Morgan Stanley Investment Management Inc. (US) | 196.152 | -316.790 | 30.6.2024 |
0,27957 % | T. Rowe Price International Ltd | 191.001 | 32.646 | 30.6.2024 |
0,27154 % | Acadian Asset Management LLC | 185.516 | 71.867 | 30.6.2024 |
0,27043 % | HRT Financial LP | 184.761 | 184.761 | 30.6.2024 |
0,26935 % | Susquehanna International Group, LLP | 184.023 | 87.509 | 30.6.2024 |
0,24105 % | UBS Asset Management (Americas), Inc. | 164.685 | 11.026 | 31.3.2023 |
0,23239 % | PDT Partners, LLC | 158.770 | 158.770 | 30.6.2024 |
0,22347 % | BlackRock Investment Management, LLC | 152.672 | 11.782 | 30.6.2024 |
0,21688 % | Parametric Portfolio Associates LLC | 148.170 | 38.770 | 30.6.2024 |
0,21592 % | Manulife Investment Management (North America) Limited | 147.519 | -653 | 30.6.2024 |
0,21358 % | Cantor Fitzgerald, L.P | 145.919 | 145.919 | 30.6.2024 |
0,21246 % | Renaissance Technologies LLC | 145.153 | -15.900 | 30.6.2024 |
0,20395 % | DWS Investments UK Limited | 139.336 | 790 | 30.6.2024 |
0,19914 % | J. Goldman & Co., L.P. | 136.050 | 136.050 | 30.6.2024 |
0,19803 % | Lewis Tanya | 135.293 | -12.860 | 13.6.2023 |
0,18362 % | Jump Financial, LLC | 125.450 | 104.509 | 30.6.2024 |
0,16164 % | BNY Mellon Asset Management | 110.434 | 5.886 | 30.6.2024 |
0,14969 % | Connor, Clark & Lunn Investment Management Ltd. | 102.269 | -110.384 | 30.6.2024 |
0,13720 % | T. Rowe Price Investment Management, Inc. | 93.734 | -171 | 31.8.2024 |
0,13616 % | Allianz Global Investors GmbH | 93.025 | 0 | 31.8.2024 |
0,13503 % | Sarchi (Christopher) | 92.252 | -2.218 | 16.5.2024 |
0,13142 % | BlackRock Advisors (UK) Limited | 89.788 | 5.213 | 30.9.2024 |
0,13060 % | Goldman Sachs Asset Management, L.P. | 89.227 | 15.650 | 30.6.2024 |
0,12443 % | Aperio Group, LLC | 85.010 | 3.063 | 30.6.2024 |
0,12430 % | Rhumbline Advisers Ltd. Partnership | 84.923 | 5.732 | 30.6.2024 |
0,12394 % | BofA Global Research (US) | 84.674 | -291.878 | 30.6.2024 |
0,12368 % | Schweizerische Nationalbank | 84.500 | 14.700 | 30.6.2024 |
0,12300 % | Algert Global LLC | 84.033 | 4.340 | 30.6.2024 |
0,12247 % | Jacobs Levy Equity Management, Inc. | 83.674 | -49.521 | 30.6.2024 |
0,12215 % | Medical Strategy GmbH | 83.456 | -205.777 | 31.12.2023 |
0,11368 % | Fisher Investments | 77.663 | 0 | 30.6.2024 |
0,11169 % | BlackRock Asset Management Ireland Limited | 76.305 | 121 | 30.6.2024 |
0,11138 % | Voya Investment Management LLC | 76.098 | 59.377 | 30.6.2024 |
0,10638 % | Dimensional Fund Advisors, Ltd. | 72.680 | 0 | 30.9.2024 |
0,10569 % | Cubist Systematic Strategies, LLC | 72.207 | 53.313 | 30.6.2024 |
0,10512 % | Los Angeles Capital Management LLC | 71.815 | 5.410 | 30.6.2024 |
0,10262 % | Campbell & Company, Inc. | 70.113 | 70.113 | 30.6.2024 |
0,10215 % | Mellon Investments Corporation | 69.792 | 13.550 | 30.6.2024 |
0,10001 % | Verition Fund Management LLC | 68.325 | 51.987 | 30.6.2024 |
0,09950 % | AllianceBernstein L.P. | 67.980 | 21.250 | 30.6.2024 |
0,09840 % | Invesco Capital Management LLC | 67.229 | 1.048 | 30.6.2024 |
0,09671 % | Atom Investors LP | 66.071 | 66.071 | 30.6.2024 |
0,08958 % | Trexquant Investment LP | 61.198 | -39.236 | 30.6.2024 |
0,08731 % | Barclays Bank PLC | 59.652 | -48.830 | 30.6.2024 |
0,08431 % | T. Rowe Price Japan, Inc. | 57.600 | 57.600 | 30.4.2024 |
0,08349 % | PanAgora Asset Management Inc. | 57.043 | 434 | 30.6.2024 |
0,08317 % | UBS Asset Management (Switzerland) | 56.823 | 53.454 | 30.6.2024 |
0,08255 % | Asset Management One Co., Ltd. | 56.396 | 56.396 | 31.8.2023 |
0,07628 % | Y-Intercept (Hong Kong) Ltd | 52.112 | 52.112 | 30.6.2024 |
0,07433 % | American Century Investment Management, Inc. | 50.785 | 7.587 | 30.6.2024 |
0,07369 % | Patel (Sushil) | 50.345 | -38.127 | 30.6.2024 |
0,07282 % | Walleye Capital LLC | 49.754 | 19.503 | 30.6.2024 |
0,07210 % | Point72 Asia (Singapore) Pte. Ltd. | 49.261 | 49.261 | 30.6.2024 |
0,07010 % | Alps Advisors, Inc. | 47.891 | 4.597 | 30.6.2024 |
0,06992 % | Northern Trust Global Investments | 47.769 | -334 | 30.6.2024 |