6,25 % | Boxer Capital, L.L.C. | 4.407.350 | 2.967.350 | 8.1.2024 |
5,34 % | Samsara BioCapital, LLC | 3.768.035 | 900.000 | 29.3.2024 |
5,06 % | New Enterprise Associates (NEA) | 3.568.781 | 0 | 27.3.2024 |
4,89 % | Adage Capital Management, L.P. | 3.450.000 | -250.000 | 31.12.2023 |
4,82 % | Deerfield Management Company, L.P. | 3.400.000 | 0 | 31.12.2023 |
4,48 % | GSK plc | 3.161.432 | 3.161.432 | 27.3.2024 |
4,02 % | EQT Life Sciences | 2.836.539 | 2.836.539 | 8.2.2024 |
3,87 % | Commodore Capital LP | 2.730.000 | 0 | 31.12.2023 |
3,13 % | BlackRock Institutional Trust Company, N.A. | 2.208.990 | -193.835 | 31.12.2023 |
2,21 % | The Vanguard Group, Inc. | 1.560.518 | 61.778 | 31.12.2023 |
15,31 % | RA Capital Management, LP | 10.805.129 | 3.000.000 | 27.3.2024 |
1,89 % | SR One Capital Management, LP | 1.333.333 | 0 | 31.12.2023 |
1,66 % | Wasatch Global Investors Inc | 1.168.492 | -931.207 | 31.3.2024 |
0,93 % | Renaissance Technologies LLC | 657.772 | 145.200 | 31.12.2023 |
0,93 % | Geode Capital Management, L.L.C. | 653.740 | 21.013 | 31.12.2023 |
0,87 % | State Street Global Advisors (US) | 611.849 | 4.545 | 31.12.2023 |
0,78 % | Tang Capital Management, LLC | 550.000 | -553.638 | 31.12.2023 |
0,66 % | T. Rowe Price Investment Management, Inc. | 462.838 | 32.488 | 31.12.2023 |
0,64 % | Alyeska Investment Group, L.P. | 450.731 | -549.269 | 31.12.2023 |
0,59 % | Columbia Threadneedle Investments (UK) | 418.024 | 418.024 | 29.2.2024 |
0,54 % | Bridgeway Capital Management, LLC | 379.467 | -225.700 | 31.12.2023 |
0,49 % | Superstring Capital Management LP | 347.381 | 347.381 | 31.12.2023 |
0,48 % | JPMorgan Asset Management U.K. Limited | 337.607 | 0 | 31.12.2023 |
0,42 % | BlackRock Financial Management, Inc. | 293.606 | -20.759 | 31.12.2023 |
0,39 % | Northern Trust Investments, Inc. | 276.431 | -1.964 | 31.12.2023 |
0,36 % | Marshall Wace LLP | 250.667 | 250.667 | 31.12.2023 |
0,35 % | Jefferies LLC | 250.000 | 0 | 31.12.2023 |
0,29 % | Stifel, Nicolaus & Company, Incorporated | 207.264 | -319.362 | 31.12.2023 |
0,27 % | Invesco Capital Management LLC | 193.602 | -71.767 | 31.12.2023 |
0,21 % | Two Sigma Investments, LP | 150.645 | 72.545 | 31.12.2023 |
0,21 % | Jane Street Capital, L.L.C. | 146.231 | 146.231 | 31.12.2023 |
0,21 % | Trager (James) | 145.415 | -4.143 | 12.2.2024 |
0,20 % | Innovis Asset Management LLC | 138.962 | 138.962 | 30.9.2023 |
0,20 % | Fidelity Management & Research Company LLC | 138.713 | 134.355 | 31.12.2023 |
0,17 % | BofA Global Research (US) | 122.145 | 10.367 | 31.12.2023 |
0,17 % | Hastings (Paul J) | 121.280 | -150.000 | 4.3.2024 |
0,16 % | Parametric Portfolio Associates LLC | 114.991 | -37.906 | 31.12.2023 |
0,16 % | Shook (David M.D.) | 110.980 | 52.448 | 16.1.2024 |
0,15 % | Medical Strategy GmbH | 108.136 | 0 | 30.9.2023 |
0,15 % | Millennium Management LLC | 105.869 | 91.707 | 31.12.2023 |
0,14 % | ACCI Capital Investments SGIIC, SA | 100.000 | -20.000 | 31.12.2023 |
0,14 % | IndexIQ Advisors LLC | 97.660 | -2.634 | 31.12.2023 |
0,14 % | BlackRock Investment Management, LLC | 95.616 | -788 | 31.12.2023 |
0,13 % | Morgan Stanley & Co. LLC | 91.581 | 31.351 | 31.12.2023 |
0,13 % | Nuveen LLC | 90.767 | 9.374 | 31.12.2023 |
0,13 % | Acadian Asset Management LLC | 90.669 | 26.120 | 31.12.2023 |
0,12 % | Davis (Aaron I) | 84.900 | 84.900 | 8.1.2024 |
0,12 % | BNY Mellon Asset Management | 82.728 | -1.093 | 31.12.2023 |
0,11 % | Barclays Bank PLC | 81.139 | 35.997 | 31.12.2023 |
0,11 % | Brandenberger (Ralph Erik) | 79.972 | -1.604 | 1.3.2024 |
0,10 % | Charles Schwab Investment Management, Inc. | 69.109 | 0 | 31.12.2023 |
0,09 % | AllianceBernstein L.P. | 66.820 | -4.000 | 31.12.2023 |
0,09 % | PGIM Quantitative Solutions LLC | 63.280 | -19.800 | 31.12.2023 |
0,08 % | Goldman Sachs & Company, Inc. | 58.371 | 12.836 | 31.12.2023 |
0,08 % | Dimensional Fund Advisors, L.P. | 56.587 | 32.172 | 31.12.2023 |
0,08 % | Levin (Alyssa) | 56.000 | 56.000 | 4.1.2024 |
0,08 % | Leo Wealth, LLC | 54.848 | 0 | 31.12.2023 |
0,07 % | Hager (Alicia J) | 52.842 | 51.446 | 16.1.2024 |
0,07 % | Rhumbline Advisers Ltd. Partnership | 49.330 | 0 | 31.12.2023 |
0,06 % | Connor, Clark & Lunn Investment Management Ltd. | 45.426 | 30.995 | 31.12.2023 |
0,06 % | Avantis Investors | 45.155 | 18.824 | 31.3.2024 |
0,06 % | Northern Trust Global Investments | 44.318 | 81 | 31.12.2023 |
0,06 % | Dimensional Fund Advisors, Ltd. | 43.054 | 2.763 | 31.1.2024 |
0,06 % | T. Rowe Price Japan, Inc. | 39.498 | 39.498 | 31.8.2023 |
0,05 % | Squarepoint Capital LLP | 36.642 | 36.642 | 31.12.2023 |
0,05 % | UBS Financial Services, Inc. | 34.284 | 19.978 | 31.12.2023 |
0,05 % | Amundi Asset Management, SAS | 32.469 | 0 | 31.12.2023 |
0,04 % | Mahmood (Nadir Ahmeduddin) | 30.676 | -526 | 20.6.2023 |
0,04 % | American Century Investment Management, Inc. | 29.348 | 7.531 | 31.12.2023 |
0,04 % | Tekla Capital Management LLC_NLE | 28.988 | 0 | 30.6.2023 |
0,04 % | abrdn Inc. | 28.988 | 28.988 | 31.12.2023 |
0,04 % | Denali Advisors, LLC | 26.500 | 26.500 | 31.3.2024 |
0,04 % | DWS Investments UK Limited | 25.401 | 25.401 | 31.12.2023 |
0,03 % | Susquehanna Portfolio Strategies, LLC | 23.411 | 23.411 | 31.12.2023 |
0,03 % | Mellon Investments Corporation | 23.244 | 0 | 31.12.2023 |
0,03 % | State Street Global Advisors Ireland Limited | 23.015 | -84 | 30.4.2023 |
0,03 % | T. Rowe Price International Ltd | 22.502 | 0 | 31.1.2024 |
0,03 % | Holistic Planning, L.L.C. | 21.200 | 21.200 | 31.12.2023 |
0,03 % | Goldman Sachs Asset Management, L.P. | 20.797 | -5.166 | 31.12.2023 |
0,03 % | Forefront Analytics, LLC | 20.767 | -18.890 | 31.12.2023 |
0,03 % | Abaris Investment Management AG | 20.000 | 20.000 | 30.6.2023 |
0,03 % | JPMorgan Private Bank (United States) | 19.599 | 19.599 | 31.12.2023 |
0,03 % | HSBC Global Asset Management (UK) Limited | 18.837 | 24 | 31.12.2023 |
0,03 % | Susquehanna International Group, LLP | 18.285 | -236.838 | 31.12.2023 |
0,03 % | Simplex Trading, LLC | 17.877 | 6.602 | 31.12.2023 |
0,02 % | Bailard, Inc. | 16.113 | -18.300 | 31.12.2023 |
0,02 % | Principal Global Investors (Equity) | 15.793 | 1.288 | 31.12.2023 |
0,02 % | SunAmerica Asset Management, LLC | 15.030 | -61 | 31.12.2023 |
0,02 % | Vanguard Personalized Indexing Management, LLC | 14.226 | 2.613 | 31.12.2023 |
0,02 % | Mariner Wealth Advisors | 13.474 | -17.474 | 31.12.2023 |
0,02 % | Sierra Summit Advisors LLC | 11.801 | 11.801 | 31.12.2023 |
0,02 % | Vaughan Nelson Investment Management, L.P. | 11.789 | 0 | 31.12.2023 |
0,02 % | SG Americas Securities, L.L.C. | 10.857 | 10.857 | 31.12.2023 |
0,02 % | Wellington Management Company, LLP | 10.806 | -65 | 29.2.2024 |
0,02 % | Sawtooth Asset Management, Inc. | 10.608 | 10.608 | 31.12.2023 |
0,02 % | Bleakley Financial Group LLC | 10.608 | 10.608 | 31.12.2023 |
0,01 % | Columbia Threadneedle Investments (US) | 10.276 | -127 | 31.12.2023 |
0,01 % | Wells Fargo Bank, N.A. | 9.314 | 1.840 | 31.12.2023 |
0,01 % | Invesco Advisers, Inc. | 8.150 | 8.150 | 31.12.2023 |
0,01 % | Morgan Stanley Smith Barney LLC | 7.786 | 1.701 | 31.12.2023 |