15,31122 % | RA Capital Management, LP | 10.805.129 | 0 | 30.6.2024 |
5,88215 % | Commodore Capital LP | 4.151.034 | 986.034 | 30.6.2024 |
5,38351 % | Deerfield Management Company, L.P. | 3.799.143 | -1.394.944 | 30.6.2024 |
5,33943 % | Samsara BioCapital, LLC | 3.768.035 | 0 | 30.6.2024 |
5,13345 % | BlackRock Institutional Trust Company, N.A. | 3.622.676 | 1.119.858 | 30.6.2024 |
5,10132 % | Adage Capital Management, L.P. | 3.600.000 | -200.000 | 30.6.2024 |
5,05708 % | New Enterprise Associates (NEA) | 3.568.781 | 0 | 30.6.2024 |
4,87970 % | Boxer Capital, L.L.C. | 3.443.606 | -2.163.744 | 10.10.2024 |
4,72344 % | SR One Capital Management, LP | 3.333.333 | 0 | 30.6.2024 |
4,47985 % | GSK plc | 3.161.432 | 3.161.432 | 27.3.2024 |
4,42884 % | Citadel Advisors LLC | 3.125.434 | 2.703.200 | 30.6.2024 |
4,18928 % | The Vanguard Group, Inc. | 2.956.374 | 990.103 | 30.6.2024 |
4,01947 % | EQT Life Sciences | 2.836.539 | 2.836.539 | 8.2.2024 |
1,97330 % | Wasatch Global Investors Inc | 1.392.555 | 224.063 | 30.6.2024 |
1,67348 % | Columbia Threadneedle Investments (UK) | 1.180.973 | 72.437 | 30.6.2024 |
1,61131 % | Geode Capital Management, L.L.C. | 1.137.099 | 322.691 | 30.6.2024 |
1,53393 % | State Street Global Advisors (US) | 1.082.493 | 453.338 | 30.6.2024 |
1,29713 % | Alyeska Investment Group, L.P. | 915.382 | 377.802 | 30.6.2024 |
1,29357 % | Renaissance Technologies LLC | 912.872 | 98.000 | 30.6.2024 |
1,24132 % | Superstring Capital Management LP | 875.999 | -313.194 | 30.6.2024 |
1,14576 % | T. Rowe Price Investment Management, Inc. | 808.566 | -546.755 | 30.6.2024 |
1,13363 % | OrbiMed Advisors, LLC | 800.000 | 0 | 30.6.2024 |
0,89008 % | Woodline Partners LP | 628.129 | 3.000 | 30.6.2024 |
0,77937 % | Tang Capital Management, LLC | 550.000 | 0 | 30.6.2024 |
0,64655 % | Two Sigma Investments, LP | 456.267 | 208.120 | 30.6.2024 |
0,62346 % | Marshall Wace LLP | 439.973 | 254.104 | 30.6.2024 |
0,43001 % | Acadian Asset Management LLC | 303.461 | 300.767 | 30.6.2024 |
0,42938 % | Northern Trust Investments, Inc. | 303.015 | 31.293 | 30.6.2024 |
0,39915 % | Millennium Management LLC | 281.677 | 245.251 | 30.6.2024 |
0,39531 % | JPMorgan Asset Management U.K. Limited | 278.969 | -53.606 | 30.6.2024 |
0,38435 % | Nuveen LLC | 271.235 | 39.306 | 30.6.2024 |
0,37717 % | BlackRock Financial Management, Inc. | 266.168 | 38.612 | 30.6.2024 |
0,35697 % | Cubist Systematic Strategies, LLC | 251.914 | 251.914 | 30.6.2024 |
0,35426 % | Jefferies LLC | 250.000 | 200.000 | 30.6.2024 |
0,34009 % | Octagon Capital Advisors LP | 240.000 | 0 | 30.6.2024 |
0,33469 % | Blackstone Alternative Asset Management, L.P. | 236.190 | 236.190 | 30.6.2024 |
0,28341 % | Affinity Asset Advisors LLC | 200.000 | 200.000 | 30.6.2024 |
0,25392 % | Squarepoint Capital LLP | 179.194 | 81.998 | 30.6.2024 |
0,24558 % | Wellington Management Company, LLP | 173.306 | 43.932 | 30.6.2024 |
0,24014 % | Bridgeway Capital Management, LLC | 169.467 | 0 | 30.6.2024 |
0,22714 % | BlackRock Investment Management, LLC | 160.296 | 75.860 | 30.6.2024 |
0,22493 % | AQR Capital Management, LLC | 158.736 | 158.736 | 30.6.2024 |
0,22320 % | Morgan Stanley & Co. LLC | 157.509 | 114.851 | 30.6.2024 |
0,20594 % | Charles Schwab Investment Management, Inc. | 145.332 | 55.904 | 30.6.2024 |
0,20541 % | Trager (James) | 144.959 | -456 | 18.6.2024 |
0,19835 % | State of Wisconsin Investment Board | 139.975 | 91.875 | 30.6.2024 |
0,19828 % | Goldman Sachs & Company, Inc. | 139.923 | 113.182 | 30.6.2024 |
0,19691 % | Innovis Asset Management LLC | 138.962 | 138.962 | 30.9.2023 |
0,19272 % | Abaris Investment Management AG | 136.000 | 116.000 | 31.12.2023 |
0,19138 % | Parametric Portfolio Associates LLC | 135.059 | 9.832 | 30.6.2024 |
0,18774 % | Federated MDTA LLC | 132.488 | 132.013 | 30.6.2024 |
0,18748 % | Dimensional Fund Advisors, L.P. | 132.306 | 35.643 | 30.6.2024 |
0,16589 % | D. E. Shaw & Co., L.P. | 117.070 | 117.070 | 30.6.2024 |
0,16297 % | BofA Global Research (US) | 115.009 | 74.637 | 30.6.2024 |
0,16252 % | BNY Mellon Asset Management | 114.691 | 46.039 | 30.6.2024 |
0,15357 % | Jane Street Capital, L.L.C. | 108.377 | -13.650 | 30.6.2024 |
0,12606 % | Barclays Bank PLC | 88.958 | 49.832 | 30.6.2024 |
0,12031 % | Davis (Aaron I) | 84.900 | 84.900 | 8.1.2024 |
0,11905 % | Rhumbline Advisers Ltd. Partnership | 84.011 | 33.117 | 30.6.2024 |
0,11546 % | Goldman Sachs Asset Management, L.P. | 81.481 | 55.614 | 30.6.2024 |
0,11434 % | AllianceBernstein L.P. | 80.690 | 13.870 | 30.6.2024 |
0,11300 % | Brandenberger (Ralph Erik) | 79.743 | -229 | 18.6.2024 |
0,11110 % | Stifel, Nicolaus & Company, Incorporated | 78.401 | -15.533 | 30.6.2024 |
0,10331 % | UBS Financial Services, Inc. | 72.903 | 41.388 | 30.6.2024 |
0,10232 % | American Century Investment Management, Inc. | 72.205 | 24.033 | 30.6.2024 |
0,09889 % | Hastings (Paul J) | 69.787 | -1.770 | 18.6.2024 |
0,09709 % | Schonfeld Strategic Advisors LLC | 68.517 | -331.583 | 30.6.2024 |
0,09572 % | Fidelity Management & Research Company LLC | 67.549 | 2.601 | 30.6.2024 |
0,09523 % | Jump Financial, LLC | 67.205 | 67.205 | 30.6.2024 |
0,08371 % | Dimensional Fund Advisors, Ltd. | 59.074 | 7.228 | 30.9.2024 |
0,08144 % | Mellon Investments Corporation | 57.471 | 30.573 | 30.6.2024 |
0,07794 % | ACCI Capital Investments SGIIC, SA | 55.000 | 5.000 | 31.7.2024 |
0,07458 % | Citi Investment Research (US) | 52.634 | 3.253 | 30.6.2024 |
0,07326 % | Jennison Associates LLC | 51.700 | 0 | 31.8.2024 |
0,06904 % | Hager (Alicia J) | 48.719 | -3.396 | 16.7.2024 |
0,06399 % | Avantis Investors | 45.155 | 18.824 | 31.3.2024 |
0,06256 % | PGIM Quantitative Solutions LLC | 44.150 | 44.150 | 30.6.2024 |
0,05810 % | Bellecapital AG | 41.000 | 24.000 | 31.3.2024 |
0,05712 % | Northern Trust Global Investments | 40.307 | -5.198 | 30.6.2024 |
0,05597 % | T. Rowe Price Japan, Inc. | 39.498 | 39.498 | 31.8.2023 |
0,05575 % | Shook (David M.D.) | 39.342 | 1.352 | 21.8.2024 |
0,05312 % | Simplicity Wealth, LLC | 37.486 | 21.659 | 30.6.2024 |
0,05002 % | Verition Fund Management LLC | 35.298 | 35.298 | 30.6.2024 |
0,04421 % | MetLife Investment Management, LLC | 31.197 | 15.228 | 30.6.2024 |
0,04347 % | Mahmood (Nadir Ahmeduddin) | 30.676 | -526 | 20.6.2023 |
0,04108 % | abrdn Inc. | 28.988 | 0 | 30.9.2024 |
0,04034 % | Corebridge Financial Inc | 28.466 | 28.466 | 30.6.2024 |
0,03294 % | Wells Fargo Bank, N.A. | 23.248 | 12.563 | 30.6.2024 |
0,03282 % | Alpine Global Management, LLC | 23.161 | 23.161 | 30.6.2024 |
0,03261 % | State Street Global Advisors Ireland Limited | 23.015 | -84 | 30.4.2023 |
0,03195 % | JPMorgan Private Bank (United States) | 22.549 | 10.694 | 30.6.2024 |
0,02958 % | Y-Intercept (Hong Kong) Ltd | 20.872 | 20.872 | 30.6.2024 |
0,02935 % | Manulife Investment Management (North America) Limited | 20.710 | 9.975 | 30.6.2024 |
0,02919 % | SG Americas Securities, L.L.C. | 20.597 | 20.597 | 30.9.2024 |
0,02622 % | Susquehanna International Group, LLP | 18.500 | -17.910 | 30.6.2024 |
0,02550 % | Voya Investment Management LLC | 17.994 | 11.388 | 30.6.2024 |
0,02399 % | T. Rowe Price International Ltd | 16.928 | 16.928 | 30.6.2024 |
0,02166 % | Bleakley Financial Group LLC | 15.284 | -22.202 | 30.9.2024 |
0,02154 % | Holistic Planning, L.L.C. | 15.200 | 0 | 30.6.2024 |
0,02123 % | Bayesian Capital Management, LP | 14.979 | 14.979 | 30.6.2024 |