10.03904 % | Bain Capital Life Sciences Investors, LLC | 16,915,784 | 0 | |
8.89424 % | New Enterprise Associates (NEA) | 14,986,793 | 0 | |
5.82712 % | BlackRock Institutional Trust Company, N.A. | 9,818,698 | 1,756,735 | |
4.91991 % | The Vanguard Group, Inc. | 8,290,050 | 462,323 | |
4.33866 % | Acorn Bioventures L.P. | 7,310,650 | 0 | |
4.23354 % | OrbiMed Advisors, LLC | 7,133,515 | 0 | |
2.74403 % | Kingdon Capital Management, L.L.C. | 4,623,683 | 1,150,000 | |
2.53787 % | Adage Capital Management, L.P. | 4,276,315 | 0 | |
2.40415 % | Soleus Capital Management, L.P. | 4,051,000 | -528,926 | |
2.10413 % | Perceptive Advisors LLC | 3,545,454 | 0 | |
2.08637 % | Geode Capital Management, L.L.C. | 3,515,538 | 570,114 | |
1.82556 % | AXA Investment Managers UK Ltd. | 3,076,077 | 1,705 | |
1.64023 % | State Street Global Advisors (US) | 2,763,790 | 240,235 | |
1.62374 % | Medical Strategy GmbH | 2,735,996 | -20,300 | |
1.51125 % | Ensign Peak Advisors, Inc. | 2,546,458 | 111,032 | |
1.48356 % | Sio Capital Management, LLC | 2,499,800 | -1,088,627 | |
0.75353 % | Schonfeld Strategic Advisors LLC | 1,269,693 | 354,693 | |
0.68874 % | UBS O'Connor LLC | 1,160,521 | -175,000 | |
0.60891 % | Ragan (Paula) | 1,026,016 | 260,748 | |
0.58093 % | Northern Trust Investments, Inc. | 978,870 | 2,010 | |
0.47870 % | Parkman Healthcare Partners LLC | 806,616 | 1,257 | |
0.39111 % | Velan Capital Investment Management LP | 659,020 | 659,020 | |
0.32231 % | Point72 Asset Management, L.P. | 543,084 | -106,916 | |
0.29599 % | Nuveen LLC | 498,745 | 60,631 | |
0.29030 % | K2 & Associates Investment Management Inc. | 489,158 | 489,158 | |
0.26954 % | BlackRock Investment Management, LLC | 454,167 | 105,319 | |
0.26623 % | Diametric Capital | 448,594 | 448,594 | |
0.26006 % | Charles Schwab Investment Management, Inc. | 438,208 | 114,365 | |
0.25166 % | AQR Capital Management, LLC | 424,042 | 388,115 | |
0.23923 % | BlackRock Financial Management, Inc. | 403,098 | 78,042 | |
0.23028 % | Taveras (Arthur PhD) | 388,026 | 153,725 | |
0.21806 % | Dibiase (Mary) | 367,436 | 162,950 | |
0.20997 % | BNY Mellon Asset Management | 353,803 | 85,080 | |
0.20381 % | Millennium Management LLC | 343,416 | 84,657 | |
0.19881 % | New Leaf Venture Partners LLC | 335,000 | 0 | |
0.13486 % | Hudson Bay Capital Management LP | 227,246 | 227,246 | |
0.11563 % | Stewart (Murray) | 194,838 | 45,000 | |
0.11113 % | Rhumbline Advisers Ltd. Partnership | 187,246 | 23,831 | |
0.10741 % | Knott Partners Management, LLC | 180,993 | 0 | |
0.10639 % | Morgan Stanley & Co. LLC | 179,273 | -1,177,341 | |
0.10506 % | Pale Fire Capital SE | 177,032 | 138,966 | |
0.09749 % | Stifel, Nicolaus & Company, Incorporated | 164,267 | 78,042 | |
0.09748 % | Group One Trading, L.P. | 164,248 | 143,002 | |
0.09695 % | Prelude Capital Management, LLC | 163,367 | 163,367 | |
0.08871 % | Goldman Sachs & Company, Inc. | 149,477 | -883,269 | |
0.08012 % | Woods (Keith) | 135,000 | 45,000 | |
0.07249 % | Jane Street Capital, L.L.C. | 122,151 | 44,699 | |
0.07221 % | Wyzga (Michael S) | 121,667 | 45,000 | |
0.06859 % | Mellon Investments Corporation | 115,569 | 48,318 | |
0.06602 % | XTX Markets LLC | 111,245 | 111,245 | |
0.06503 % | AllianceBernstein L.P. | 109,570 | 63,890 | |
0.06453 % | Susquehanna International Group, LLP | 108,734 | -393,931 | |
0.05737 % | Aliski (William) | 96,667 | 45,000 | |
0.05737 % | de (Craecker Francoise) | 96,667 | 45,000 | |
0.05737 % | McGirr (David W J) | 96,667 | 45,000 | |
0.05737 % | Lawton (Alison Frances) | 96,667 | 45,000 | |
0.05737 % | Bridger (Gary J) | 96,667 | 45,000 | |
0.05568 % | Barclays Bank PLC | 93,821 | -354,887 | |
0.05398 % | BofA Global Research (US) | 90,957 | -11,755 | |
0.05365 % | Corebridge Financial Inc | 90,404 | 90,404 | |
0.04578 % | Northern Trust Global Investments | 77,136 | -492 | |
0.04475 % | Simplex Trading, LLC | 75,405 | 75,405 | |
0.04451 % | Bank Vontobel AG | 75,000 | 0 | |
0.04250 % | JPMorgan Private Bank (United States) | 71,614 | 23,341 | |
0.03766 % | Mirae Asset Global Investments (USA) LLC | 63,453 | 63,452 | |
0.03681 % | UBS Financial Services, Inc. | 62,030 | -67,054 | |
0.03664 % | SunAmerica Asset Management, LLC | 61,735 | 537 | |
0.03484 % | Voya Investment Management LLC | 58,702 | 18,104 | |
0.03417 % | Invesco Advisers, Inc. | 57,574 | 3,165 | |
0.03264 % | SG Americas Securities, L.L.C. | 55,004 | 55,004 | |
0.03193 % | Wells Fargo Bank, N.A. | 53,799 | 12,835 | |
0.03065 % | New York State Common Retirement Fund | 51,639 | 0 | |
0.02999 % | Virtu Americas LLC | 50,537 | 50,537 | |
0.02981 % | T. Rowe Price International Ltd | 50,226 | 10,919 | |
0.02879 % | Baldry (Mark) | 48,509 | 23,819 | |
0.02874 % | Morgan Stanley Smith Barney LLC | 48,432 | -303 | |
0.02671 % | CIBC Private Wealth Management | 45,000 | 0 | |
0.02434 % | Invesco Capital Management LLC | 41,006 | -3,207 | |
0.02385 % | DWS Investments UK Limited | 40,184 | -12,222 | |
0.02170 % | Citi Investment Research (US) | 36,566 | -90,485 | |
0.01864 % | Principal Global Investors (Equity) | 31,410 | 17,719 | |
0.01790 % | PNC Investments LLC | 30,158 | 0 | |
0.01691 % | Private Advisor Group LLC | 28,500 | 3,000 | |
0.01600 % | Tower Research Capital LLC | 26,963 | 10,754 | |
0.01543 % | Lemanik Invest SA | 26,000 | 0 | |
0.01499 % | Commonwealth Financial Network | 25,250 | 150 | |
0.01473 % | Vaughan Nelson Investment Management, L.P. | 24,819 | 0 | |
0.01289 % | Goldman Sachs Asset Management, L.P. | 21,713 | -4,471 | |
0.01276 % | OneDigital Investment Advisors LLC | 21,500 | -6,973 | |
0.01187 % | Cassady Schiller Wealth Management, LLC | 20,000 | 0 | |
0.01104 % | Legal & General Investment Management Ltd. | 18,609 | 7,283 | |
0.01060 % | Bleichroeder LP | 17,865 | 0 | |
0.01014 % | BNP Paribas Securities Corp. North America | 17,085 | -44,490 | |
0.00996 % | ProShare Advisors LLC | 16,779 | -5,728 | |
0.00950 % | Lexaurum Advisors, LLC | 16,000 | 0 | |
0.00938 % | RBC Wealth Management, International | 15,805 | 13,000 | |
0.00902 % | Victory Capital Management Inc. | 15,204 | -749 | |
0.00838 % | HSBC Global Asset Management (UK) Limited | 14,125 | 0 | |
0.00819 % | Holistic Planning, L.L.C. | 13,800 | 0 | |
0.00786 % | Mackenzie Investments | 13,238 | -16 | |