9.45562 % | The Vanguard Group, Inc. | 9,017,825 | 239,870 | |
9.18529 % | BlackRock Institutional Trust Company, N.A. | 8,760,014 | 4,206,149 | |
4.53059 % | Capital International Investors | 4,320,827 | -496,690 | |
4.34287 % | State Street Global Advisors (US) | 4,141,793 | 2,019,302 | |
4.00060 % | Janus Henderson Investors | 3,815,368 | -1,076,049 | |
3.93852 % | Capital Research Global Investors | 3,756,164 | 1,097,418 | |
3.33422 % | Barry (Richard J) | 3,179,842 | 49,677 | |
3.14564 % | Avoro Capital Advisors LLC | 3,000,000 | -1,344,444 | |
2.51540 % | Capital World Investors | 2,398,936 | 693,124 | |
2.40642 % | Farallon Capital Management, L.L.C. | 2,295,000 | -158,500 | |
2.35951 % | Morgan Stanley & Co. LLC | 2,250,263 | 1,656,692 | |
2.16161 % | Wellington Management Company, LLP | 2,061,526 | -1,184,272 | |
2.05372 % | T. Rowe Price Investment Management, Inc. | 1,958,635 | 27,088 | |
1.79125 % | Fidelity Management & Research Company LLC | 1,708,316 | 580,692 | |
1.73225 % | Geode Capital Management, L.L.C. | 1,652,048 | 131,678 | |
1.47564 % | EcoR1 Capital, LLC | 1,407,322 | -512,513 | |
1.45736 % | DWS Investment GmbH | 1,389,886 | -41,173 | |
1.20439 % | Two Sigma Investments, LP | 1,148,628 | 144,612 | |
1.14976 % | JP Morgan Asset Management | 1,096,529 | -101,885 | |
1.12562 % | Casdin Capital, LLC | 1,073,500 | 4,500 | |
1.00369 % | Pictet Asset Management Ltd. | 957,218 | -301,318 | |
0.99358 % | Paradigm BioCapital Advisors LP | 947,574 | -130,772 | |
0.96931 % | Norges Bank Investment Management (NBIM) | 924,428 | 87,579 | |
0.95797 % | Mellon Investments Corporation | 913,615 | -53,965 | |
0.91132 % | Jane Street Capital, L.L.C. | 869,129 | 591,025 | |
0.82876 % | BlackRock Financial Management, Inc. | 790,387 | 27,040 | |
0.81349 % | Citadel Advisors LLC | 775,821 | -747,256 | |
0.72393 % | Jacobs Levy Equity Management, Inc. | 690,408 | 110,771 | |
0.68156 % | Boxer Capital, L.L.C. | 650,000 | 0 | |
0.67736 % | OrbiMed Advisors, LLC | 646,000 | -51,500 | |
0.67597 % | Thrivent Asset Management, LLC | 644,675 | 37,940 | |
0.63412 % | Charles Schwab Investment Management, Inc. | 604,757 | 15,318 | |
0.60006 % | Millennium Management LLC | 572,275 | -301,872 | |
0.59103 % | BNY Wealth | 563,665 | -9,636 | |
0.55879 % | Balyasny Asset Management LP | 532,918 | 23,713 | |
0.55124 % | Northern Trust Investments, Inc. | 525,714 | 165,900 | |
0.53857 % | BofA Global Research (US) | 513,638 | 84,081 | |
0.52290 % | Federated Hermes Global Investment Management Corp. | 498,692 | -110,483 | |
0.48678 % | Alkeon Capital Management LLC | 464,239 | 81,628 | |
0.47456 % | Nuveen LLC | 452,592 | -62,018 | |
0.45203 % | abrdn Inc. | 431,098 | 101,253 | |
0.42576 % | Eagle Asset Management, Inc. | 406,046 | 192,617 | |
0.41942 % | Adage Capital Management, L.P. | 400,000 | -70,000 | |
0.40926 % | Ingram (Douglas S) | 390,307 | 0 | |
0.39860 % | Barclays Bank PLC | 380,142 | 21,483 | |
0.39517 % | Fiera Capital Inc. | 376,876 | 13,916 | |
0.39267 % | JPMorgan Asset Management U.K. Limited | 374,489 | 587 | |
0.38063 % | Principal Global Investors (Equity) | 363,011 | 317,277 | |
0.37680 % | Invesco Advisers, Inc. | 359,356 | 270,278 | |
0.36909 % | Renaissance Technologies LLC | 352,000 | -38,278 | |
0.36779 % | UBS Financial Services, Inc. | 350,764 | 73,574 | |
0.36705 % | Assenagon Asset Management S.A. | 350,052 | -9,644 | |
0.35726 % | BNY Mellon Asset Management | 340,720 | 173,183 | |
0.34214 % | Mizuho Markets Americas, L.L.C | 326,300 | 35,500 | |
0.34210 % | CPR Asset Management | 326,260 | -16,933 | |
0.34111 % | RBC Wealth Management, International | 325,312 | 20,268 | |
0.33851 % | Voya Investment Management LLC | 322,835 | -14,799 | |
0.33370 % | Fred Alger Management, LLC | 318,252 | 60,686 | |
0.31115 % | Newton Investment Management North America, LLC | 296,743 | -47,405 | |
0.30951 % | AHL Partners LLP | 295,179 | 181,773 | |
0.30263 % | Voloridge Investment Management, LLC | 288,617 | -141,852 | |
0.29779 % | Rock Springs Capital Management LP | 284,000 | -43,600 | |
0.29504 % | T. Rowe Price Associates, Inc. | 281,379 | -166,778 | |
0.28924 % | BlackRock Asset Management Ireland Limited | 275,850 | 17,804 | |
0.28409 % | Rhumbline Advisers Ltd. Partnership | 270,941 | 160,942 | |
0.26779 % | Dimensional Fund Advisors, L.P. | 255,396 | 31,105 | |
0.26510 % | Bank of Nova Scotia | 252,825 | -168,711 | |
0.26457 % | Bellevue Asset Management AG | 252,321 | 800 | |
0.26401 % | Chambers (Michael Andrew) | 251,791 | 69,845 | |
0.25393 % | Franklin Advisers, Inc. | 242,174 | 10,078 | |
0.24888 % | ClearBridge Investments, LLC | 237,354 | 86,138 | |
0.24148 % | CPP Investment Board | 230,300 | -10,200 | |
0.23969 % | BlackRock Investment Management (UK) Ltd. | 228,588 | -8,771 | |
0.23962 % | Eventide Asset Management, LLC | 228,529 | 93,063 | |
0.23802 % | Caption Management, LLC | 227,000 | 76,654 | |
0.23627 % | Ensign Peak Advisors, Inc. | 225,328 | 38,090 | |
0.22906 % | Goldman Sachs Asset Management, L.P. | 218,458 | -18,830 | |
0.22899 % | Goldman Sachs & Company, Inc. | 218,389 | 211,195 | |
0.22478 % | AllianceBernstein L.P. | 214,371 | -103,866 | |
0.21855 % | Pictet Asset Management (Japan) Ltd. | 208,430 | -25,274 | |
0.21350 % | Ikarian Capital LLC | 203,612 | 51,334 | |
0.21147 % | Palo Alto Investors LP | 201,683 | 418 | |
0.21094 % | JPMorgan Private Bank (United States) | 201,175 | 85,266 | |
0.20892 % | Behrens (M Kathleen) | 199,247 | -746 | |
0.20536 % | Sofinnova Investments, Inc | 195,852 | -31,636 | |
0.20425 % | Susquehanna International Group, LLP | 194,794 | -86,903 | |
0.20057 % | BlackRock Investment Management, LLC | 191,287 | 113,222 | |
0.19049 % | First Turn Management, LLC | 181,669 | -40,079 | |
0.18848 % | Parametric Portfolio Associates LLC | 179,749 | 66,567 | |
0.18274 % | William Blair & Company, L.L.C. (Research) | 174,282 | 131,112 | |
0.18137 % | Deutsche Asset Management Americas | 172,974 | 172,974 | |
0.17994 % | Columbia Wanger Asset Management, LLC | 171,605 | 0 | |
0.17415 % | Schweizerische Nationalbank | 166,083 | -100 | |
0.16681 % | TD Asset Management Inc. | 159,082 | -17,490 | |
0.15962 % | Fidelity Institutional Asset Management | 152,229 | -68,717 | |
0.15922 % | California Public Employees' Retirement System | 151,851 | 28,066 | |
0.15728 % | Logos Global Management LLC | 150,000 | -250,000 | |
0.15728 % | Camber Capital Management LP | 150,000 | -435,000 | |
0.15530 % | Cubist Systematic Strategies, LLC | 148,114 | 54,500 | |
0.15478 % | Legal & General Investment Management Ltd. | 147,614 | 58,732 | |