8.64 % | The Vanguard Group, Inc. | 8,331,674 | 155,579 | |
7.89 % | BlackRock Institutional Trust Company, N.A. | 7,609,214 | 675,921 | |
4.91 % | State Street Global Advisors (US) | 4,735,861 | 1,002,936 | |
3.52 % | Nikko Asset Management Co., Ltd. | 3,399,318 | -79,244 | |
2.55 % | Wellington Management Company, LLP | 2,456,917 | -195,077 | |
2.33 % | Deep Track Capital LP | 2,250,000 | 250,000 | |
2.09 % | Federated Hermes Global Investment Management Corp. | 2,016,300 | 244,722 | |
2.05 % | Geode Capital Management, L.L.C. | 1,973,269 | 93,024 | |
11.39 % | ARK Investment Management LLC | 10,989,282 | -423,167 | |
1.81 % | T. Rowe Price Associates, Inc. | 1,746,041 | -216,717 | |
1.72 % | AllianceBernstein L.P. | 1,663,742 | 116,630 | |
1.52 % | Rokos Capital Management LLP | 1,463,630 | 74,334 | |
1.50 % | Casdin Capital, LLC | 1,450,000 | 271,925 | |
1.31 % | Citadel Advisors LLC | 1,259,292 | -710,891 | |
1.21 % | Dimensional Fund Advisors, L.P. | 1,170,829 | 60,748 | |
1.10 % | Morgan Stanley & Co. LLC | 1,064,198 | 178,956 | |
1.07 % | Himension Capital (Singapore) Pte. Ltd | 1,030,621 | -114,470 | |
1.03 % | Fidelity Management & Research Company LLC | 992,006 | -215,658 | |
1.03 % | Chevy Chase Trust Company | 991,175 | -11,780 | |
1.02 % | Morgan Stanley Investment Management Inc. (US) | 980,108 | -879,931 | |
1.01 % | Two Sigma Investments, LP | 971,904 | 554,297 | |
0.93 % | Leonard (John M) | 900,124 | 113,586 | |
0.92 % | Marshall Wace LLP | 890,498 | 890,498 | |
0.92 % | Pictet Asset Management Ltd. | 883,470 | -53,847 | |
0.82 % | BlackRock Financial Management, Inc. | 791,366 | 85,542 | |
0.76 % | Northern Trust Investments, Inc. | 731,355 | 15,586 | |
0.73 % | Charles Schwab Investment Management, Inc. | 700,228 | 18,987 | |
0.58 % | Discovery Value Fund | 561,561 | 0 | |
0.56 % | Norges Bank Investment Management (NBIM) | 536,172 | -321,106 | |
0.50 % | Goldman Sachs & Company, Inc. | 486,337 | 33,377 | |
0.49 % | Nuveen LLC | 472,818 | -28,152 | |
0.46 % | Avidity Partners Management LP | 447,434 | 68,334 | |
0.40 % | BioImpact Capital LLC | 382,598 | -162,041 | |
0.39 % | Eventide Asset Management, LLC | 372,665 | 0 | |
0.35 % | Goldman Sachs Asset Management, L.P. | 338,190 | -5,113 | |
0.35 % | JPMorgan Asset Management U.K. Limited | 335,990 | -7,416 | |
0.34 % | Rafferty Asset Management LLC | 328,998 | 77,873 | |
0.34 % | Barclays Bank PLC | 328,446 | 131,369 | |
0.34 % | UBS Asset Management (Switzerland) | 326,204 | 21,099 | |
0.33 % | Nikko Asset Management Americas, Inc. | 318,369 | -52,071 | |
0.31 % | Morgan Stanley Smith Barney LLC | 299,384 | 67,115 | |
0.31 % | HOOPP Investment Management | 298,000 | 298,000 | |
0.30 % | Columbia Threadneedle Investments (US) | 292,519 | 259,164 | |
0.30 % | Capital Advisors, Inc. (OK) | 284,738 | 73,379 | |
0.29 % | BlackRock Investment Management, LLC | 280,706 | 36,574 | |
0.29 % | Temasek Holdings Pte. Ltd. | 279,693 | 0 | |
0.28 % | UBS Financial Services, Inc. | 274,524 | 150,517 | |
0.28 % | Eagle Asset Management, Inc. | 269,558 | 26,867 | |
0.28 % | Vestmark Advisory Solutions, Inc | 265,981 | 265,981 | |
0.27 % | Granahan Investment Management, LLC | 257,791 | 52,600 | |
0.26 % | American Century Investment Management, Inc. | 248,529 | -18,684 | |
0.25 % | Qube Research & Technologies Ltd | 240,691 | 195,432 | |
0.25 % | BNY Mellon Asset Management | 239,887 | 6,972 | |
0.25 % | Hudson Bay Capital Management LP | 237,500 | 52,300 | |
0.22 % | Contrarius Investment Management Ltd. | 214,401 | -17,461 | |
0.22 % | BofA Global Research (US) | 211,174 | 15,051 | |
0.22 % | BNP Paribas Securities Corp. North America | 210,161 | 1,930 | |
0.21 % | Jane Street Capital, L.L.C. | 204,285 | 116,308 | |
0.21 % | Frazier Healthcare Partners | 203,684 | 0 | |
0.21 % | Walleye Capital LLC | 203,327 | 19,872 | |
0.21 % | Tang Capital Management, LLC | 200,000 | -197,600 | |
0.20 % | Susquehanna International Group, LLP | 195,499 | 87,710 | |
0.20 % | Fidelity Institutional Asset Management | 194,597 | -90,767 | |
0.20 % | Medical Strategy GmbH | 194,224 | 0 | |
0.19 % | Mirae Asset Global Investments (USA) LLC | 185,858 | -100,885 | |
0.18 % | Wells Fargo Advisors | 175,589 | 13,389 | |
0.18 % | Orchard Capital Management LLC | 170,006 | 10,851 | |
0.17 % | Citi Investment Research (US) | 167,606 | -97,798 | |
0.17 % | Parametric Portfolio Associates LLC | 166,998 | 85,511 | |
0.17 % | Schweizerische Nationalbank | 165,700 | -8,700 | |
0.17 % | Rhumbline Advisers Ltd. Partnership | 163,358 | -627 | |
0.17 % | PDT Partners, LLC | 160,997 | 123,920 | |
0.16 % | abrdn Inc. | 154,269 | 154,269 | |
0.16 % | Tekla Capital Management LLC_NLE | 154,269 | 0 | |
0.16 % | Managed Account Advisors LLC | 154,197 | -63,554 | |
0.16 % | Coho Partners, Ltd. | 151,803 | 151,803 | |
0.16 % | Wanjia Asset Management Co., Ltd. | 150,000 | 30,000 | |
0.15 % | BlackRock Advisors (UK) Limited | 148,072 | 7,181 | |
0.15 % | AHL Partners LLP | 146,072 | 137,709 | |
0.15 % | Mellon Investments Corporation | 144,771 | 1,366 | |
0.15 % | Northern Trust Global Investments | 140,380 | -30,466 | |
0.14 % | Neuberger Berman, LLC | 135,637 | -10,784 | |
0.14 % | Raymond James & Associates, Inc. | 134,371 | 29,997 | |
0.14 % | DWS Investments UK Limited | 132,813 | 90,332 | |
0.13 % | JP Morgan Asset Management | 129,655 | -60,765 | |
0.13 % | California Public Employees' Retirement System | 126,624 | 0 | |
0.13 % | Credit Suisse Funds AG | 125,339 | 12,056 | |
0.13 % | BlackRock Investment Management (UK) Ltd. | 123,970 | 54,379 | |
0.12 % | RBC Capital Markets Wealth Management | 120,290 | 63,835 | |
0.12 % | The Regents of the University of California | 117,315 | 5,875 | |
0.12 % | BlackRock Asset Management Ireland Limited | 114,844 | 4,818 | |
0.11 % | Russell Investments Trust Company | 108,404 | -18,863 | |
0.11 % | JPMorgan Private Bank (United States) | 102,414 | 82,807 | |
0.11 % | Lazard Asset Management, L.L.C. | 102,233 | -3,917 | |
0.10 % | Opaleye Management Inc. | 99,000 | 99,000 | |
0.10 % | DWS Investment GmbH | 95,330 | -2,475 | |
0.10 % | Voya Investment Management LLC | 94,720 | 38,170 | |
0.09 % | Candriam Luxembourg S.A. | 91,275 | 0 | |
0.09 % | Candriam Belgium S.A. | 91,275 | 40,000 | |
0.09 % | SELECTRA Management Company S.A. | 90,627 | 1,060 | |