8.88744 % | BVF Partners L.P. | 8,902,972 | 0 | |
7.28028 % | Soleus Capital Management, L.P. | 7,293,007 | 0 | |
4.44664 % | Avidity Partners Management LP | 4,454,408 | -3,511,992 | |
3.92469 % | The Vanguard Group, Inc. | 3,931,548 | 7,785 | |
2.57895 % | Focus Partners Wealth, LLC | 2,583,457 | 415,104 | |
2.10598 % | Gratus Capital LLC | 2,109,664 | 56,857 | |
1.78504 % | Omega Fund Management, LLC | 1,788,160 | 0 | |
1.39616 % | Adage Capital Management, L.P. | 1,398,600 | 0 | |
1.05764 % | abrdn Inc. | 1,059,484 | 1,059,484 | |
0.97445 % | Geode Capital Management, L.L.C. | 976,152 | 23,862 | |
0.94799 % | Susquehanna International Group, LLP | 949,648 | 65,910 | |
0.91257 % | Ikarian Capital LLC | 914,170 | -700,000 | |
0.89843 % | 683 Capital Management LLC | 900,000 | 200,000 | |
0.66830 % | Renaissance Technologies LLC | 669,464 | 102,841 | |
0.65193 % | BlackRock Institutional Trust Company, N.A. | 653,067 | -12,324 | |
0.56256 % | Marshall Wace LLP | 563,543 | 145,660 | |
0.53143 % | Morgan Stanley & Co. LLC | 532,355 | -535,900 | |
0.37622 % | Vitt (Daniel) | 376,877 | 0 | |
0.33895 % | Muehler (Andreas M.D.) | 339,538 | 17,789 | |
0.30341 % | State Street Global Advisors (US) | 303,945 | 0 | |
0.27198 % | Innovis Asset Management LLC | 272,457 | 86,217 | |
0.24045 % | Boothbay Fund Management, LLC | 240,873 | -184,441 | |
0.23068 % | Northern Trust Investments, Inc. | 231,086 | 0 | |
0.22997 % | Rudick (Richard Alan) | 230,375 | 143,075 | |
0.22803 % | Laurion Capital Management LP | 228,431 | 228,431 | |
0.20704 % | Jane Street Capital, L.L.C. | 207,401 | 152,726 | |
0.19965 % | Neermann (Joerg) | 200,000 | 100,000 | |
0.17707 % | GSA Capital Partners LLP | 177,381 | 61,439 | |
0.14879 % | UBS Financial Services, Inc. | 149,050 | 131,669 | |
0.11982 % | Connor, Clark & Lunn Investment Management Ltd. | 120,027 | -39,140 | |
0.11480 % | Bridgeway Capital Management, LLC | 115,000 | -100,000 | |
0.11405 % | Simplex Trading, LLC | 114,253 | -1,709 | |
0.10074 % | Millennium Management LLC | 100,916 | -478,767 | |
0.09534 % | Whaley (Glenn) | 95,510 | 45,000 | |
0.06174 % | Group One Trading, L.P. | 61,850 | -12,056 | |
0.05811 % | BlackRock Investment Management (UK) Ltd. | 58,212 | 13,141 | |
0.05619 % | Barclays Capital Inc. | 56,287 | -28,012 | |
0.05502 % | Envestnet Asset Management, Inc. | 55,114 | 55,114 | |
0.05478 % | PGGM Vermogensbeheer B.V. | 54,880 | 54,880 | |
0.05231 % | Homrich Berg | 52,400 | -26,000 | |
0.04878 % | UBS O'Connor LLC | 48,865 | -155,714 | |
0.04569 % | Schonfeld Strategic Advisors LLC | 45,774 | 45,774 | |
0.04446 % | Quadrature Capital LLP | 44,536 | 44,536 | |
0.03656 % | Jain Global LLC | 36,622 | 36,622 | |
0.03535 % | Invesco Capital Management LLC | 35,409 | -1,402 | |
0.03494 % | Creative Planning, Inc. | 35,000 | 0 | |
0.03493 % | Qube Research & Technologies Ltd | 34,989 | -130,772 | |
0.02978 % | Sweet Financial Partners, LLC | 29,829 | 0 | |
0.02945 % | Morgan Stanley Smith Barney LLC | 29,501 | -7,000 | |
0.02941 % | BlackRock (Netherlands) B.V. | 29,462 | -25,429 | |
0.02747 % | Dimensional Fund Advisors, L.P. | 27,521 | 0 | |
0.02496 % | Charles Schwab Investment Management, Inc. | 25,000 | 0 | |
0.02199 % | Nash (Duane D) | 22,032 | 0 | |
0.02091 % | Avantis Investors | 20,942 | 0 | |
0.01953 % | BofA Global Research (US) | 19,566 | 41 | |
0.01801 % | Ring Mountain Capital, LLC | 18,039 | 0 | |
0.01799 % | Newton Investment Management North America, LLC | 18,020 | 0 | |
0.01545 % | BlackRock Investment Management, LLC | 15,475 | -1,796 | |
0.01472 % | Cubist Systematic Strategies, LLC | 14,742 | -8,570 | |
0.01455 % | Hudson Bay Capital Management LP | 14,573 | 14,573 | |
0.01434 % | Dimensional Fund Advisors, Ltd. | 14,370 | 0 | |
0.01373 % | BNY Mellon Asset Management | 13,758 | 0 | |
0.01198 % | Balboa Wealth Partners, Inc. | 12,000 | 0 | |
0.01115 % | Level Four Advisory Services, LLC | 11,167 | 0 | |
0.01048 % | PFG Investments, LLC | 10,500 | 0 | |
0.01040 % | The Retirement Planning Group, Inc. | 10,417 | 10,417 | |
0.00998 % | Crescent Grove Advisors, LLC | 10,000 | 10,000 | |
0.00998 % | Private Advisor Group LLC | 10,000 | 0 | |
0.00998 % | Dynamic Wealth Advisors | 10,000 | 10,000 | |
0.00863 % | Carson Wealth Management Group | 8,642 | 0 | |
0.00575 % | Morgan Stanley & Co. International Plc | 5,756 | 5,756 | |
0.00519 % | Marble Trail Advisors | 5,200 | 0 | |
0.00469 % | Blackstone Alternative Investment Advisors LLC | 4,700 | -2,600 | |
0.00359 % | SBI Securities Co., Ltd. | 3,594 | 1,385 | |
0.00199 % | Osaic Holdings, Inc. | 1,997 | 1,997 | |
0.00150 % | Northwestern Mutual Capital, LLC | 1,500 | 0 | |
0.00091 % | BlackRock Advisors (UK) Limited | 912 | -677 | |
0.00086 % | Rise Advisors, LLC | 862 | 862 | |
0.00086 % | J.P. Morgan Securities LLC | 858 | -4,951 | |
0.00041 % | J.P. Morgan Securities plc | 407 | 0 | |
0.00020 % | Wells Fargo Advisors | 197 | 0 | |
0.00013 % | Northern Trust Global Investments | 132 | 0 | |
0.00004 % | RBC Dominion Securities, Inc. | 45 | 0 | |
0.00001 % | BNP Paribas Securities Corp. North America | 6 | 0 | |
0.00000 % | Caldwell Sutter Capital, Inc | 5 | 0 | |
0.00000 % | Parallel Advisors, LLC | 2 | 0 | |
0 % | ACCI Capital Investments SGIIC, SA | 0 | -150,000 | |
0 % | L2 Asset Management, LLC | 0 | -356 | |
0 % | Benefit Financial Services Group, LLC | 0 | -3,000 | |
0 % | Squarepoint Capital LLP | 0 | -22,054 | |
0 % | Wolverine Trading, LLC | 0 | -16,789 | |
0 % | Summit Trail Advisors, LLC | 0 | -21,600 | |
0 % | Independent Financial Partners | 0 | -2,000 | |
0 % | National Bank of Canada | 0 | -250 | |
0 % | HRT Financial LP | 0 | -12,648 | |
0 % | LPL Financial LLC | 0 | -11,000 | |
0 % | Ground Swell Capital, LLC | 0 | -11,357 | |
0 % | RTW Investments L.P. | 0 | -4,567,717 | |
0 % | Virtu Americas LLC | 0 | -12,128 | |
0 % | Verition Fund Management LLC | 0 | -245,308 | |