59.92246 % | Innoviva Inc | 28,672,897 | 0 | |
4.52425 % | AstraZeneca PLC | 2,164,855 | 0 | |
2.13322 % | TPG Capital, L.P. | 1,020,748 | 0 | |
1.23428 % | Eventide Asset Management, LLC | 590,602 | 0 | |
0.94034 % | The Vanguard Group, Inc. | 449,955 | 23,720 | |
0.67575 % | Renaissance Technologies LLC | 323,345 | 10,800 | |
0.56059 % | Two Sigma Investments, LP | 268,242 | -146,988 | |
0.39623 % | Tommasi (Ruben Ph.D.) | 189,596 | 125,000 | |
0.37842 % | Perros (Manoussos) | 181,072 | 125,000 | |
0.35020 % | Gutch (Michael Ph.D.) | 167,572 | 125,000 | |
0.35020 % | Keiley (Elizabeth M) | 167,572 | 125,000 | |
0.35020 % | Ronsheim (Matthew) | 167,572 | 125,000 | |
0.29796 % | Altarac (David) | 142,572 | 125,000 | |
0.29695 % | Mueller (John Patrick) | 142,092 | 125,000 | |
0.26123 % | Triola (Anna Diaz) | 125,000 | 125,000 | |
0.22989 % | Bridgeway Capital Management, LLC | 110,000 | 0 | |
0.21510 % | Geode Capital Management, L.L.C. | 102,927 | 9,759 | |
0.17117 % | Dimensional Fund Advisors, L.P. | 81,904 | 55,834 | |
0.16823 % | Wagner (Kristie Ann) | 80,500 | 80,500 | |
0.15381 % | Janney Montgomery Scott LLC | 73,597 | 5,000 | |
0.13656 % | Susquehanna International Group, LLP | 65,346 | 65,346 | |
0.11664 % | Acadian Asset Management LLC | 55,813 | 35,297 | |
0.08423 % | State Street Global Advisors (US) | 40,305 | 0 | |
0.05747 % | Mayer (Howard) | 27,500 | 27,500 | |
0.05747 % | Meek (David D) | 27,500 | 27,500 | |
0.05747 % | Hastings (David C) | 27,500 | 27,500 | |
0.05747 % | Behanna (Heather A. PHD) | 27,500 | 27,500 | |
0.05395 % | BlackRock Institutional Trust Company, N.A. | 25,813 | 1,373 | |
0.05374 % | Northern Trust Investments, Inc. | 25,713 | 0 | |
0.05092 % | Virtu Americas LLC | 24,367 | -7,264 | |
0.04853 % | Occudo Quantitative Strategies LP | 23,221 | 764 | |
0.04438 % | Dimensional Fund Advisors, Ltd. | 21,234 | 0 | |
0.02131 % | Citadel Advisors LLC | 10,197 | 10,197 | |
0.02090 % | T. Rowe Price Associates, Inc. | 10,000 | 0 | |
0.00836 % | Tower Research Capital LLC | 4,000 | -11,093 | |
0.00836 % | Spire Wealth Management, LLC | 4,000 | 0 | |
0.00773 % | Blackstone Alternative Investment Advisors LLC | 3,700 | 1,500 | |
0.00455 % | BlackRock Investment Management, LLC | 2,179 | 0 | |
0.00455 % | Lord, Abbett & Co. LLC | 2,179 | 0 | |
0.00387 % | Manulife Investment Management (North America) Limited | 1,850 | 0 | |
0.00313 % | Wells Fargo Advisors | 1,500 | 0 | |
0.00303 % | The Bollard Group, LLC | 1,448 | 0 | |
0.00209 % | CAPTRUST Financial Advisors | 1,000 | 1,000 | |
0.00137 % | FinTrust Capital Advisors, LLC | 654 | 654 | |
0.00024 % | Wells Fargo Bank, N.A. | 114 | 1 | |
0.00021 % | Trustcore Financial Services, LLC | 100 | 0 | |
0.00012 % | Innealta Capital, LLC | 56 | -82 | |
0.00004 % | BofA Global Research (US) | 18 | 18 | |
0.00000 % | Amplius Wealth Advisors, LLC | 2 | 2 | |
0.00000 % | Morgan Stanley & Co. LLC | 1 | 1 | |
0 % | Susquehanna Fundamental Investments, LLC | 0 | -21,394 | |
0 % | Qube Research & Technologies Ltd | 0 | -60,355 | |
0 % | Pivotal Bioventure Partners Investment Advisor LLC | 0 | -1,176,378 | |
0 % | Squarepoint Capital LLP | 0 | -91,725 | |
0 % | Advisor Group, Inc | 0 | -2,100 | |
0 % | Alambic Investment Management, L.P. | 0 | -20,682 | |
0 % | Private Advisor Group LLC | 0 | -1,000 | |
0 % | Raymond James Financial Services Advisors, Inc. | 0 | -34,569 | |
0 % | Anson Funds Management LP. | 0 | -92,626 | |
0 % | Barclays Bank PLC | 0 | -112 | |
0 % | Armistice Capital LLC | 0 | -3,510,981 | |
0 % | Prospera Financial Services, Inc. | 0 | -5,936 | |
0 % | Morgan Stanley Smith Barney LLC | 0 | -84 | |
0 % | Jaffetilchin Investment Partners LLC | 0 | -11,000 | |
0 % | Clarus Ventures, LLC | 0 | -568,004 | |
0 % | Jane Street Capital, L.L.C. | 0 | -32,177 | |
0 % | Sofinnova Investments, Inc | 0 | -1,012,408 | |
0 % | Novo Holdings A/S | 0 | -1,153,911 | |
0 % | Frazier Healthcare Partners | 0 | -199,953 | |
0 % | CPP Investment Board | 0 | -30,000 | |
0 % | Millennium Management LLC | 0 | -49,478 | |
0 % | Valu-Trac Investment Management Ltd. | 0 | -46,913 | |
0 % | Federated Hermes MDTA LLC | 0 | -566 | |
0 % | Fidelity Management & Research Company LLC | 0 | -400 | |
0 % | RBC Capital Markets Wealth Management | 0 | -1,000 | |
0 % | Bailard, Inc. | 0 | -1,046 | |
0 % | Paloma Partners Management Company | 0 | -18,891 | |
0 % | Granahan Investment Management, Inc. | 0 | -10,064 | |
0 % | J.P. Morgan Securities LLC | 0 | -3 | |
0 % | Alberta Investment Management Corporation | 0 | -65,000 | |
0 % | UBS Financial Services, Inc. | 0 | -5,310 | |
0 % | CaaS Capital Management LP | 0 | -579,379 | |