9.21529 % | Capital International Investors | 7,865,253 | 28,179 | |
9.11369 % | ARK Investment Management LLC | 7,778,536 | -378,492 | |
6.76086 % | Capital World Investors | 5,770,391 | 0 | |
3.69246 % | Nikko Asset Management Co., Ltd. | 3,151,514 | -117,271 | |
3.69246 % | Nikko Asset Management Americas, Inc. | 3,151,514 | -117,271 | |
3.19936 % | T. Rowe Price Investment Management, Inc. | 2,730,652 | 26,321 | |
2.87697 % | BlackRock Institutional Trust Company, N.A. | 2,455,497 | 156,478 | |
2.80455 % | State Street Global Advisors (US) | 2,393,684 | 898,476 | |
2.75699 % | Fidelity Management & Research Company LLC | 2,353,091 | 113,408 | |
2.34336 % | Capital Research Global Investors | 2,000,060 | 0 | |
2.02837 % | The Vanguard Group, Inc. | 1,731,211 | 110,214 | |
1.86040 % | New Enterprise Associates (NEA) | 1,587,854 | 0 | |
1.62774 % | EcoR1 Capital, LLC | 1,389,276 | 0 | |
1.22900 % | SR One Capital Management, LP | 1,048,951 | 0 | |
1.22900 % | George (Simeon J.) | 1,048,951 | 1,048,951 | |
1.17893 % | Loomis, Sayles & Company, L.P. | 1,006,213 | -19,030 | |
1.14003 % | Geode Capital Management, L.L.C. | 973,018 | 63,720 | |
1.11324 % | Dimensional Fund Advisors, L.P. | 950,149 | 19,094 | |
1.01223 % | BofA Global Research (US) | 863,937 | 80,992 | |
0.84078 % | Charles Schwab Investment Management, Inc. | 717,606 | 48,414 | |
0.80342 % | Contrarius Investment Management Ltd. | 685,716 | 19,716 | |
0.76181 % | Norges Bank Investment Management (NBIM) | 650,208 | 32,622 | |
0.72367 % | Bellevue Asset Management AG | 617,649 | -2,301 | |
0.64677 % | UBS Asset Management (UK) Ltd. | 552,014 | 498,184 | |
0.62097 % | Farallon Capital Management, L.L.C. | 530,000 | 530,000 | |
0.58413 % | Versant Ventures | 498,558 | 0 | |
0.52444 % | Federated Hermes Global Investment Management Corp. | 447,606 | 0 | |
0.47501 % | Baillie Gifford & Co. | 405,425 | 9,510 | |
0.46713 % | UBS Financial Services, Inc. | 398,699 | 78,322 | |
0.46462 % | T. Rowe Price Associates, Inc. | 396,555 | -179,539 | |
0.41000 % | Jane Street Capital, L.L.C. | 349,931 | 174,859 | |
0.37083 % | Tang Capital Management, LLC | 316,500 | 200,000 | |
0.35218 % | Capital Advisors, Inc. (OK) | 300,589 | 22,583 | |
0.34144 % | Kulkarni (Samarth) | 291,417 | 4,040 | |
0.33105 % | Morgan Stanley Smith Barney LLC | 282,553 | -14,014 | |
0.31497 % | Squarepoint Capital LLP | 268,823 | -5,207 | |
0.30559 % | Susquehanna International Group, LLP | 260,821 | 187,583 | |
0.29017 % | JPMorgan Asset Management U.K. Limited | 247,661 | -48,953 | |
0.28033 % | Morgan Stanley & Co. LLC | 239,261 | -480,079 | |
0.26667 % | Wells Fargo Advisors | 227,599 | 11,826 | |
0.25215 % | Northern Trust Investments, Inc. | 215,207 | 5,994 | |
0.23608 % | Cutter Capital Management, LP | 201,497 | 81,312 | |
0.23240 % | Armistice Capital LLC | 198,357 | 6,357 | |
0.23153 % | Vestmark Advisory Solutions, Inc | 197,614 | -51,930 | |
0.22538 % | Goldman Sachs & Company, Inc. | 192,359 | 69,726 | |
0.22309 % | Pictet Asset Management Ltd. | 190,408 | -130,115 | |
0.21862 % | Marshall Wace LLP | 186,591 | 186,591 | |
0.21390 % | Rafferty Asset Management LLC | 182,561 | 58,987 | |
0.19332 % | Spear Holdings RSC, Ltd | 165,000 | 0 | |
0.19083 % | Columbia Threadneedle Investments (US) | 162,877 | 6,096 | |
0.18705 % | TD Asset Management Inc. | 159,644 | -7,150 | |
0.18594 % | Schweizerische Nationalbank | 158,700 | 9,800 | |
0.17575 % | Integral Health Asset Management, LLC | 150,000 | -70,000 | |
0.17504 % | Capital International Sarl | 149,393 | 7,485 | |
0.17462 % | Pictet Asset Management (Japan) Ltd. | 149,034 | 149,034 | |
0.17161 % | TwinBeech Capital LP | 146,473 | 146,473 | |
0.16771 % | California Public Employees' Retirement System | 143,140 | 35,411 | |
0.16703 % | Citadel Advisors LLC | 142,562 | -94,538 | |
0.15973 % | BNP Paribas Securities Corp. North America | 136,333 | -12,609 | |
0.15814 % | William Blair & Company, L.L.C. (Research) | 134,969 | -12,921 | |
0.15736 % | BlackRock Advisors (UK) Limited | 134,303 | 1,611 | |
0.14868 % | Nordea Funds Oy | 126,900 | -21,800 | |
0.14861 % | Woodline Partners LP | 126,839 | -36,738 | |
0.14778 % | Capital International Ltd. | 126,131 | -639 | |
0.14032 % | BlackRock Asset Management Ireland Limited | 119,760 | 2,877 | |
0.13602 % | LPL Financial LLC | 116,091 | 10,171 | |
0.13436 % | Reynders, McVeigh Capital Management, LLC | 114,673 | 17,694 | |
0.12020 % | Legal & General Investment Management Ltd. | 102,588 | 19,678 | |
0.11972 % | Capital International, Inc. | 102,178 | 10,517 | |
0.11853 % | BlackRock Financial Management, Inc. | 101,169 | 73,861 | |
0.11716 % | Baker Bros. Advisors LP | 100,000 | 100,000 | |
0.11632 % | Marshall & Melhorn LLC | 99,280 | 760 | |
0.11017 % | Rockefeller Capital Management | 94,027 | 14,907 | |
0.10623 % | Balyasny Asset Management LP | 90,664 | 90,664 | |
0.10357 % | Osaic Holdings, Inc. | 88,401 | -2,650 | |
0.10250 % | Goldman Sachs Asset Management International | 87,486 | 0 | |
0.10066 % | Slow Capital, Inc. | 85,910 | 6,694 | |
0.09321 % | Mirae Asset Global Investments (USA) LLC | 79,553 | -86,993 | |
0.09085 % | Himension Capital (Singapore) Pte. Ltd | 77,542 | 8,527 | |
0.08905 % | ACATIS Investment Kapitalverwaltungsgesellschaft GmbH | 76,000 | 38,000 | |
0.08769 % | UBS Asset Management (Switzerland) | 74,843 | 18,208 | |
0.08694 % | Lazard Asset Management, L.L.C. | 74,203 | -11,937 | |
0.08552 % | Goldman Sachs Asset Management, L.P. | 72,988 | 62,924 | |
0.08542 % | California State Teachers Retirement System | 72,903 | 5,002 | |
0.08406 % | Private Advisor Group LLC | 71,747 | -5,880 | |
0.08332 % | Managed Account Advisors LLC | 71,116 | -1,262 | |
0.08305 % | SELECTRA Management Company S.A. | 70,886 | 8,136 | |
0.08280 % | BlackRock Investment Management (UK) Ltd. | 70,669 | -10,363 | |
0.08182 % | RBC Capital Markets Wealth Management | 69,831 | 4,014 | |
0.08025 % | Group One Trading, L.P. | 68,490 | 44,937 | |
0.07862 % | UBS Fund Management (Switzerland) AG | 67,101 | -615,357 | |
0.07781 % | Commonwealth Financial Network | 66,408 | 4,849 | |
0.07690 % | Dimensional Fund Advisors, Ltd. | 65,634 | 1,329 | |
0.07683 % | Barclays Bank PLC | 65,578 | -161,985 | |
0.07496 % | Congress Asset Management Company, LLP | 63,980 | -625 | |
0.07381 % | International Biotechnology Trust PLC | 63,000 | 63,000 | |
0.07287 % | Kasinger (James R.) | 62,198 | 1,024 | |
0.07239 % | Raymond James Financial Services Advisors, Inc. | 61,783 | 4,352 | |
0.06775 % | McGuire Wealth Management | 57,822 | -48 | |
0.06757 % | Harris Associates L.P. | 57,667 | -1,276 | |