18.41641 % | VenBio Partners LLC | 9,699,925 | 0 | |
14.74946 % | Fidelity Management & Research Company LLC | 7,768,541 | 262,468 | |
8.01224 % | Vivo Capital, LLC | 4,220,048 | 0 | |
7.67192 % | Tang Capital Management, LLC | 4,040,800 | 4,040,800 | |
7.66366 % | Redmile Group, LLC | 4,036,451 | -290,058 | |
6.83501 % | Vestal Point Capital, LP | 3,600,000 | 990,000 | |
5.60011 % | Lightstone Ventures, L.P. | 2,949,580 | -1,259,395 | |
4.48199 % | BlackRock Institutional Trust Company, N.A. | 2,360,662 | 425,886 | |
4.14062 % | MPM BioImpact LLC | 2,180,864 | 912,393 | |
3.80174 % | Millennium Management LLC | 2,002,374 | -959,297 | |
3.59685 % | OrbiMed Advisors, LLC | 1,894,462 | -823,508 | |
3.26759 % | The Vanguard Group, Inc. | 1,721,039 | 160,784 | |
2.99147 % | Paradigm BioCapital Advisors LP | 1,575,605 | 1,575,605 | |
1.33956 % | State Street Global Advisors (US) | 705,547 | 151,680 | |
1.32980 % | Geode Capital Management, L.L.C. | 700,406 | 95,692 | |
1.20691 % | Marshall Wace LLP | 635,679 | 514,133 | |
0.92228 % | Morgan Stanley & Co. LLC | 485,765 | 344,280 | |
0.83197 % | Renaissance Technologies LLC | 438,200 | 204,100 | |
0.83043 % | Pons (Jaume) | 437,385 | -1,937 | |
0.75369 % | Privium Fund Management BV | 396,966 | 396,966 | |
0.68317 % | Two Sigma Investments, LP | 359,826 | 284,371 | |
0.58388 % | Kennedy Capital Management LLC | 307,529 | 300,573 | |
0.57737 % | Point72 Asset Management, L.P. | 304,100 | 304,100 | |
0.46105 % | Randolph (Sophia) | 242,836 | -1,365 | |
0.44811 % | Charles Schwab Investment Management, Inc. | 236,020 | 26,261 | |
0.44052 % | Jacobs Levy Equity Management, Inc. | 232,022 | 232,022 | |
0.41869 % | Northern Trust Investments, Inc. | 220,525 | 1,600 | |
0.37866 % | Cubist Systematic Strategies, LLC | 199,441 | 199,441 | |
0.34570 % | Parametric Portfolio Associates LLC | 182,082 | -14,302 | |
0.33662 % | BlackRock Financial Management, Inc. | 177,298 | 36,315 | |
0.31777 % | Goodman (Corey S) | 167,370 | 0 | |
0.27666 % | Wellington Management Company, LLP | 145,717 | 18,680 | |
0.26581 % | Jump Financial, LLC | 140,000 | 115,194 | |
0.26042 % | Goldman Sachs & Company, Inc. | 137,164 | 24,916 | |
0.20840 % | Walleye Capital LLC | 109,762 | 71,521 | |
0.20776 % | Lettmann (Jason) | 109,429 | -2,191 | |
0.19745 % | Nuveen LLC | 103,995 | 0 | |
0.17256 % | BlackRock Investment Management, LLC | 90,887 | 14,205 | |
0.14828 % | Jane Street Capital, L.L.C. | 78,100 | 18,905 | |
0.14826 % | Goldman Sachs Asset Management, L.P. | 78,088 | 33,334 | |
0.14556 % | BNY Mellon Asset Management | 76,664 | 20,058 | |
0.14262 % | State of Wisconsin Investment Board | 75,120 | 20,754 | |
0.13949 % | Susquehanna Portfolio Strategies, LLC | 73,468 | -17,489 | |
0.13619 % | AllianceBernstein L.P. | 71,730 | 32,940 | |
0.13008 % | Citadel Advisors LLC | 68,511 | -1,166,704 | |
0.12571 % | abrdn Inc. | 66,211 | 0 | |
0.10484 % | Rhumbline Advisers Ltd. Partnership | 55,220 | 5,360 | |
0.09379 % | Schweizerische Nationalbank | 49,400 | 5,200 | |
0.09241 % | Garcia (Peter S) | 48,673 | -761 | |
0.08820 % | Fidelity Institutional Asset Management | 46,455 | 29,716 | |
0.08382 % | Balyasny Asset Management LP | 44,149 | 44,149 | |
0.07965 % | Nan Fung Life Sciences | 41,950 | 0 | |
0.07825 % | Algert Global LLC | 41,215 | 41,215 | |
0.07786 % | BofA Global Research (US) | 41,010 | -6,145 | |
0.07784 % | Deka Verm¿gensmanagement GmbH | 41,000 | 0 | |
0.07784 % | Deka Investment GmbH | 41,000 | 16,700 | |
0.07192 % | LSV Asset Management | 37,880 | 10,850 | |
0.06844 % | Pinto (Shelly) | 36,045 | -564 | |
0.06755 % | BlackRock Asset Management Ireland Limited | 35,580 | 4,043 | |
0.06558 % | Dimensional Fund Advisors, L.P. | 34,543 | -15,798 | |
0.06491 % | SEI Investments Management Corporation | 34,190 | 14,190 | |
0.06184 % | Verition Fund Management LLC | 32,571 | 32,571 | |
0.06021 % | Wealth Enhancement Advisory Services, LLC | 31,710 | 291 | |
0.05965 % | The Financial Advisory Group, Inc | 31,417 | 0 | |
0.05848 % | BlackRock Advisors (UK) Limited | 30,804 | 679 | |
0.05503 % | Avantis Investors | 28,985 | 8,467 | |
0.05492 % | Legal & General Investment Management Ltd. | 28,926 | 11,740 | |
0.05346 % | Mellon Investments Corporation | 28,157 | 5,141 | |
0.05201 % | SG Americas Securities, L.L.C. | 27,394 | 6,888 | |
0.05129 % | Connor, Clark & Lunn Investment Management Ltd. | 27,014 | -2,070 | |
0.04795 % | California State Teachers Retirement System | 25,254 | 2,457 | |
0.04747 % | LMR Partners LLP | 25,000 | 25,000 | |
0.04663 % | Susquehanna International Group, LLP | 24,561 | 859 | |
0.04546 % | Graham Capital Management, L.P. | 23,942 | 23,942 | |
0.04497 % | American Century Investment Management, Inc. | 23,685 | -5,978 | |
0.04418 % | Northern Trust Global Investments | 23,270 | -2,261 | |
0.04210 % | Sherbrooke Park Advisors LLC | 22,172 | 22,172 | |
0.03949 % | Dimensional Fund Advisors, Ltd. | 20,801 | 0 | |
0.03946 % | Quest Partners, LLC | 20,781 | -4,251 | |
0.03844 % | Assenagon Asset Management S.A. | 20,245 | 91 | |
0.03817 % | J.P. Morgan Securities LLC | 20,102 | 102 | |
0.03596 % | D. E. Shaw & Co., L.P. | 18,940 | 18,940 | |
0.03557 % | Aperio Group, LLC | 18,736 | -14,391 | |
0.03433 % | AQR Capital Management, LLC | 18,079 | 6,080 | |
0.03374 % | Corebridge Financial Inc | 17,771 | 17,771 | |
0.03288 % | Barclays Bank PLC | 17,317 | -11,318 | |
0.03254 % | UBS Fund Management (Switzerland) AG | 17,137 | 1,372 | |
0.03114 % | Occudo Quantitative Strategies LP | 16,402 | 16,402 | |
0.03064 % | MetLife Investment Management, LLC | 16,140 | 1,579 | |
0.03038 % | Abaris Investment Management AG | 16,000 | 8,000 | |
0.03007 % | Commonwealth Financial Network | 15,840 | 15,840 | |
0.02934 % | UBS Financial Services, Inc. | 15,453 | -13,621 | |
0.02766 % | Mirae Asset Global Investments (USA) LLC | 14,571 | 3,634 | |
0.02673 % | JPMorgan Private Bank (United States) | 14,077 | 3,509 | |
0.02594 % | Manulife Investment Management (North America) Limited | 13,662 | -46,457 | |
0.02468 % | SunAmerica Asset Management, LLC | 13,000 | -398 | |
0.02392 % | Engineers Gate Manager, L.P. | 12,600 | 12,600 | |
0.02377 % | New York State Common Retirement Fund | 12,522 | 0 | |
0.02160 % | Vaughan Nelson Investment Management, L.P. | 11,377 | 0 | |
0.02129 % | Voya Investment Management LLC | 11,215 | 11,215 | |