Stoke Therapeutics (STOK) Stock Price

Stoke Therapeutics Price

NASDAQ·CLOSED
24.29
​
Market closed

Over the last 4 years Stoke Therapeutics grew revenue by 180.0% annually, reaching 184.42 M USD. For Stoke Therapeutics, the net margin of -3.7% is up versus -2,823.7% a few years ago. The consensus 12-month price target for Stoke Therapeutics is 44.00 USD, about 81.1% above where the stock trades today. Of 20 analysts, 19 rate the stock a buy — an overall Buy consensus.

Stoke Therapeutics stock price

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Stoke Therapeutics business model & stock analysis

Stoke Therapeutics Inc is a biopharmaceutical company founded in 2018 by experienced scientists to develop innovative therapeutic approaches for rare genetic diseases. The company's headquarters is located in Bedford, Massachusetts, and since its inception, it has continuously invested to expand its business and its development process. In 2019, the company announced a financing round of $90 million to advance the development of its pipeline and clinical trials. Stoke Therapeutics specializes in the development of therapeutics for the treatment of rare genetic diseases caused by mutations in haploinsufficiency genes. These diseases are caused by mutations in one of the two genes that code for a specific protein. Since a single defective gene is not sufficient to maintain the normal functions of a protein, serious health problems arise. Stoke's therapeutics aim to replace the missing gene product by targeted stimulation of the healthy gene. This is achieved through the development of antisense oligonucleotide-based therapeutics. Antisense oligonucleotides are small DNA-like molecules that are able to address, recognize, and bind to specific genes. By binding to the healthy gene, they can promote its expression and thereby replace the missing protein. The company's pipeline currently includes a range of products at various stages of development, including preclinical and clinical trials. The following products are the most important: STK-001: A product developed for the treatment of severe forms of Dravet syndrome. Dravet syndrome is a rare genetic disease characterized by seizures, developmental delays, and other neurological symptoms. STK-002: A product for the treatment of haploinsufficiency in STING1-associated vasculopathic syndrome (SAVS). SAVS is a rare genetic disease characterized by cardiovascular disorders and increased susceptibility to infections. STK-005: A product for the treatment of haploinsufficiency in adrenoleukodystrophy (ALD). ALD is a rare disease characterized by inflammatory and degenerative changes in the nervous system. Due to its innovative technology and focus on rare genetic diseases, Stoke Therapeutics has attracted the attention of many investors and potential partners. In 2020, the company entered into collaboration agreements with Roche Holdings and Ribometrix Inc to accelerate the development and commercialization of its therapeutics. Overall, Stoke Therapeutics has a promising future as it is able to provide a much-needed treatment option for patients with rare genetic diseases who currently have no effective therapies available.

Frequently asked questions about Stoke Therapeutics

The business model of Stoke Therapeutics Inc revolves around developing innovative RNA-targeted therapeutics to treat severe genetic diseases. By focusing on addressing the underlying causes of diseases, Stoke Therapeutics aims to provide long-term solutions for patients. Its proprietary technology platform, Targeted Augmentation of Nuclear Gene Output (TANGO), enables the modulation of gene expression levels to restore the production of functional proteins. Stoke Therapeutics collaborates with industry partners and utilizes its expertise in RNA biology to advance potential therapies for a range of genetic disorders. Through its business model, the company aims to improve the lives of patients with severe genetic diseases through innovative and targeted treatments.

Stoke Therapeutics Inc is primarily active in the biotechnology industry.

The main competitors of Stoke Therapeutics Inc in the market include companies such as Alnylam Pharmaceuticals, Ionis Pharmaceuticals, and Akcea Therapeutics.

Stoke Therapeutics Inc is a biotechnology company founded in 2018, based in Bedford, Massachusetts. Focused on addressing the underlying causes of severe genetic diseases, Stoke Therapeutics utilizes its proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) platform. This platform enables the development of antisense oligonucleotide (ASO) therapies to increase protein levels and restore gene expression. By targeting RNA instead of DNA, Stoke Therapeutics aims to treat a range of genetic disorders, including genetic epilepsies, genetic conditions affecting the central nervous system, and other rare diseases. Their innovative approach holds promise for patients with limited treatment options, making Stoke Therapeutics a key player in the biotech industry.

Stoke Therapeutics Inc has achieved several significant milestones. The company successfully completed its initial public offering in June 2019, raising approximately $142 million in net proceeds. In January 2020, Stoke Therapeutics received the FDA's rare pediatric disease designation for its lead product candidate, STK-001, which aims to treat Dravet syndrome, a severe form of epilepsy. Furthermore, the company initiated a Phase 1/2a clinical trial of STK-001 in October 2020. Stoke Therapeutics continues to make progress in advancing its pipeline and developing innovative therapies for genetic diseases.

Stoke Therapeutics Inc is primarily present in the United States.

Stoke Therapeutics Inc represents values of innovation, collaboration, and commitment to patients. The company's corporate philosophy revolves around developing transformative treatments for severe genetic diseases. Stoke is dedicated to harnessing the power of RNA biology to address the underlying cause of such diseases. By prioritizing scientific advancement and partnerships, Stoke Therapeutics Inc aims to make a positive impact on patients' lives. The company strives to excel in translating cutting-edge research into therapeutic breakthroughs, offering hope and delivering long-term value for patients, their families, and the healthcare community.

Analysts currently set an average price target of 47.33 USD for the Stoke Therapeutics stock (median: 44.00 USD), implying +94.9 % versus the latest price. The consensus is based on 20 analyst ratings.

20 analysts currently rate the Stoke Therapeutics stock: 19 recommend buying, 1 holding and 0 selling. For 2026, analysts expect Stoke Therapeutics to generate revenue of 32.03 M USD and earnings per share of -3.54 USD.

Converted at the current exchange rate, the Stoke Therapeutics share trades at 21.69 EUR (24.29 USD).

The Stoke Therapeutics share (STOK) is listed on 3 stock exchanges, including: NASDAQ (STOK), Frankfurt (0GT.F), München (0GT.MU).

Stoke Therapeutics Inc. is a biopharmaceutical company focused on developing technologies and therapies for the treatment of rare genetic diseases. Their business model is based on the application of a novel technology platform called Targeted Augmentation of Nuclear Gene Output (TANGO), which allows for the increase or decrease of gene expression. They aim to achieve therapeutic effects by specifically augmenting gene expression through their TANGO platform, which involves developing RNA molecules known as antisense oligonucleotides (ASOs) to modulate gene expression. Stoke Therapeutics has multiple products in various stages of development, with their most advanced candidate, STK-001, targeting the treatment of autosomal recessive spinobulbar muscular atrophy (SMA). They are also working on therapies for other rare diseases such as autosomal dominant optic atrophy (ADOA) and Dravet syndrome. Overall, Stoke Therapeutics focuses on developing RNA-based therapeutics for rare genetic diseases caused by loss-of-function mutations.

The expected revenue of Stoke Therapeutics is 32.03 M USD. This figure is based on current financial data and reflects the company's business performance.

The expected profit of Stoke Therapeutics is -206.73 M USD. The net profit reflects the company's profitability after deducting all expenses.

The price-to-earnings ratio (P/E) of Stoke Therapeutics is currently -6.86. The P/E ratio compares the current share price to the earnings per share and helps investors assess the valuation of the Stoke Therapeutics stock.

The price-to-sales ratio (P/S) of Stoke Therapeutics is currently 44.28. The P/S ratio compares the market capitalization to the annual revenue and serves as a valuation metric for the Stoke Therapeutics stock.

The Eulerpool Quality Score for Stoke Therapeutics is 3/10.

The ISIN of Stoke Therapeutics is US86150R1077. The ISIN (International Securities Identification Number) is a globally unique identifier for securities.

The WKN of Stoke Therapeutics is A2PLTL. The WKN (Wertpapierkennnummer) is a six-digit German security identification number.

The ticker of Stoke Therapeutics is STOK. The ticker symbol is used to trade Stoke Therapeutics shares on the stock exchange.

Fair ValueTerminal
23.32 USD
Over-/UndervaluationTerminal
Fairly valued
Sector
Industry
Biotechnology
Number of shares
Employees
Revenue per Employee
1.08 M USD
Revenue growth Ø5 years
EBIT growth Ø5 years
Net Income growth Ø5 years
Currency
USD
Initial public offering
Jun 19, 2019
ISIN
US86150R1077
Cusip
86150R107
Sedol
BJQ05Z6
Market capitalization
1.39 B USDSmall Cap
52-Week Range
PEG
—
P/E ratio
P/Ee 2026
-6.86
P/Ee 2027
-7.02
P/Ee 2028
-10.48
P/Ee 2029
-210.81
P/Ee 2030
11.31
P/S
P/Se
44.28
EV/EBIT
—
P/B Ratio
3.94
ROE (Return on Equity)
ROA (Return on Assets)
ROCE (Return on Capital Employed)
ROIC (Return on Invested Capital)
-1.94 %
Last updated Oct 8, 2026, 1:45 AM

Stoke Therapeutics Ticker

FRANKFURT · 0GT.FMUNICH · 0GT.MUNASDAQ · STOK

Stoke Therapeutics FIGI

STOK:US · BBG00JPCBPG9STOK:UA · BBG00P8TXZ44STOK:UC · BBG00P8TXZ53STOK:UN · BBG00P8TXZ71STOK:UP · BBG00P8TXZ80STOK:UB · BBG00P8TXZB6STOK:UM · BBG00P8TXZD4STOK:UX · BBG00P8TXZF2STOK:UD · BBG00P8TXZL5STOK:UW · BBG00P8TXZN3STOK:UF · BBG00P8TXZP1STOK:VY · BBG00P8TXZQ0