Castle Biosciences (CSTL) Stock Price

Castle Biosciences Price

NASDAQ·CLOSED
35.81
+0.00 (+0.00 %)
Market closed

Revenue has compounded at 52.0% per year over the past 8 years to 344.14 M USD. Castle Biosciences's net margin stands at -7.0%, up from -33.3% several years earlier. Analysts set a median price target of 40.00 USD, implying 11.7% above the current price. Of 15 analysts, 14 rate the stock a buy — an overall Buy consensus. The stock trades about 97% above its 52-week low.

Castle Biosciences stock price

Volume
Details

Stock Price

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How to Read This Chart

This chart tracks the historical stock price of Castle Biosciences over time. You can switch between daily, weekly, and monthly views and select custom time ranges — from a single day to the full available history. Use the toggle to view price changes in absolute currency terms or as a percentage change relative to the starting date.

Total Return vs. Price Return

The "Total Return" toggle includes reinvested dividends on top of the pure price movement. This is critical because dividends can account for a significant portion of long-term returns. Historically, roughly 40 % of the S&P 500's total return has come from dividends. Always compare total return when evaluating a stock's real performance against a benchmark.

Intraday Price Data

When viewing a one-day time frame, the chart displays real-time intraday price movements. This is useful for observing how Castle Biosciences stock reacts to market openings, earnings releases, or breaking news throughout the trading session.

What to Look For

Look for long-term trends (sustained upward or downward movements over months and years), support and resistance levels (price zones where the stock repeatedly bounces or reverses), and volatility (how much the price fluctuates day to day). Comparing Castle Biosciences's price chart to a market index like the S&P 500 can reveal whether the stock is outperforming or underperforming the broader market.

Castle Biosciences Stock Price History
DateCastle Biosciences Price
9/25/202635.81 USD
9/24/202635.81 USD
9/23/202634.88 USD
9/22/202634.71 USD
9/21/202635.37 USD
9/18/202636.20 USD
9/17/202636.78 USD
9/16/202635.94 USD
9/15/202634.85 USD
9/14/202633.44 USD
9/13/202632.70 USD
9/11/202632.06 USD
9/10/202632.32 USD
9/9/202632.31 USD
9/8/202632.67 USD
9/4/202632.91 USD
9/3/202632.65 USD
9/2/202633.42 USD
9/1/202633.44 USD
8/31/202633.03 USD
8/30/202632.81 USD
8/28/202633.01 USD
8/27/202634.68 USD
8/26/202634.08 USD
8/25/202635.00 USD
8/24/202634.15 USD
8/21/202634.20 USD
8/20/202632.93 USD
8/19/202631.01 USD
8/18/202628.88 USD
Access this data via the Eulerpool API

Castle Biosciences Revenue, EBIT, Net Income

  • 3 Years

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Revenue
EBIT
Net Income
Details
Date
Revenue
EBIT
Net Income
Jan 1, 2023
219.78 M USD
-67.98 M USD
-57.47 M USD
Jan 1, 2024
331.49 M USD
8.67 M USD
18.25 M USD
Jan 1, 2025
344.14 M USD
-42.81 M USD
-24.16 M USD
Jan 1, 2026 (e)
372.59 M USD
-36.46 M USD
-37.14 M USD
Jan 1, 2027 (e)
410.34 M USD
-28.29 M USD
-28.87 M USD
Jan 1, 2028 (e)
461.43 M USD
-6.55 M USD
-10.57 M USD
Jan 1, 2029 (e)
498.05 M USD
17.44 M USD
15.32 M USD
Jan 1, 2030 (e)
541.10 M USD
32.84 M USD
29.04 M USD

Castle Biosciences Income Statement, Balance Sheet, Cash Flow Statement

Last updated Sep 27, 2026, 5:33 AM
 
REVENUEM USD
REVENUE GROWTH%
GROSS MARGIN%
GROSS INCOMEM USD
EBITM USD
EBIT MARGIN%
NET INCOMEM USD
NET INCOME GROWTH%
SHARESM
2017201820192020202120222023202420252026e2027e2028e2029e2030e
13.0022.0051.0062.0094.00137.00219.00332.00344.00372.00410.00461.00498.00541.00
–69.23131.8221.5751.6145.7459.8551.603.618.1410.2212.448.038.63
61.5477.2786.2783.8782.9876.6479.4581.6379.3679.3679.3679.3679.3679.36
8.0017.0044.0052.0078.00105.00174.00271.00273.00295.22325.38365.85395.22429.34
-10.00-4.007.00-6.00-40.00-72.00-67.008.00-42.00-36.00-28.00-6.0017.0032.00
-76.92-18.1813.73-9.68-42.55-52.55-30.592.41-12.21-9.68-6.83-1.303.415.91
-12.00-6.005.00-10.00-31.00-67.00-57.0018.00-24.00-37.00-28.00-10.0015.0029.00
–-50.00-183.33-300.00210.00116.13-14.93-131.58-233.3354.17-24.32-64.29-250.0093.33
9.7810.6518.6020.8325.3326.4027.1430.2029.3329.3329.3329.3329.3329.33
Details

Income Statement Key Figures

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Revenue and Revenue Growth

Revenue is the starting point of every income statement — it measures the total sales Castle Biosciences generates from its core business. Revenue growth (expressed as year-over-year percentage change) is one of the most important indicators of business momentum. Sustained growth above 10 % annually is generally considered strong, while declining revenue is a serious warning sign that demands investigation.

Gross Margin

Gross margin = (Revenue − Cost of Goods Sold) ÷ Revenue. It reveals what percentage of each dollar of revenue Castle Biosciences retains after direct production costs. High gross margins (above 50 %) are typical of asset-light businesses like software and brands, while capital-intensive industries like manufacturing often operate below 30 %. Compare Castle Biosciences's gross margin to industry peers and track it over time to spot improving or deteriorating pricing power.

EBIT and EBIT Margin

EBIT measures operating profit — what remains after subtracting all operating expenses (including R&D, sales, and administrative costs) from gross profit. The EBIT margin shows this as a percentage of revenue. Because it excludes interest and taxes, EBIT allows fair comparisons between companies with different debt levels and tax jurisdictions. A rising EBIT margin indicates improving operational efficiency.

Net Income and Earnings Per Share (EPS)

Net income is the company's final profit after all expenses, interest, and taxes. Dividing net income by the number of shares outstanding gives you EPS — the single most influential metric in stock valuation. Consistent EPS growth is the primary driver of long-term stock price appreciation. Always check whether EPS growth comes from genuine profit improvement or from share buybacks reducing the share count.

Shares Outstanding

The total number of shares Castle Biosciences has issued. A declining share count (through buybacks) boosts EPS and signals management confidence. A rising share count (through stock issuance) dilutes existing shareholders. Always monitor this number alongside EPS to get the full picture of per-share value creation.

Analyst Estimates

The projected figures represent consensus estimates from professional analysts. Compare these forecasts against Castle Biosciences's historical growth rates to assess whether expectations are realistic. A company that consistently beats consensus estimates tends to see its stock price rewarded over time, while repeated misses erode investor confidence.

Castle Biosciences stock margins

The Castle Biosciences margin analysis displays the gross margin, EBIT margin, as well as the profit margin of Castle Biosciences. The EBIT margin (EBIT/sales) indicates the percentage of sales that remains as operating profit. The profit margin shows the percentage of sales that remains for Castle Biosciences.
  • 3 Years

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Gross margin
EBIT margin
Profit margin
Details
Date
Gross margin
EBIT margin
Profit margin
Jan 1, 2021
83.18 %
-42.60 %
-33.26 %
Jan 1, 2022
76.65 %
-53.17 %
-49.00 %
Jan 1, 2023
79.54 %
-30.93 %
-26.15 %
Jan 1, 2024
82.01 %
2.62 %
5.50 %
Jan 1, 2025
79.39 %
-12.44 %
-7.02 %
Jan 1, 2026 (e)
79.39 %
-9.78 %
-9.97 %
Jan 1, 2027 (e)
79.39 %
-6.89 %
-7.03 %
Jan 1, 2028 (e)
79.39 %
-1.42 %
-2.29 %

Castle Biosciences Stock Revenue, EBIT, Earnings per Share

The Castle Biosciences earnings per share therefore indicates how much revenue Castle Biosciences has generated per share in a given period. The earnings before interest and taxes per share shows how much of the operating profit corresponds to each share. The earnings per share indicates how much of the profit belongs to each share.
  • 3 Years

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  • 25 Years

  • Max

Revenue per Share
EBIT per share
Earnings per Share
Details
Date
Revenue per Share
EBIT per share
Earnings per Share
Jan 1, 2021
3.71 USD
-1.58 USD
-1.24 USD
Jan 1, 2022
5.19 USD
-2.76 USD
-2.54 USD
Jan 1, 2023
8.10 USD
-2.50 USD
-2.12 USD
Jan 1, 2024
10.98 USD
0.29 USD
0.60 USD
Jan 1, 2025
11.73 USD
-1.46 USD
-0.82 USD
Jan 1, 2026 (e)
12.76 USD
-1.24 USD
-1.27 USD
Jan 1, 2027 (e)
14.06 USD
-0.96 USD
-0.99 USD
Jan 1, 2028 (e)
15.81 USD
-0.22 USD
-0.36 USD

Castle Biosciences business model & stock analysis

Castle Biosciences Inc is an American company that was founded in 2007. The company's goal is to develop and distribute innovative diagnostic tests for various types of cancer. Castle Biosciences is headquartered in Friendswood, Texas, and has numerous branches throughout North America. The company currently has around 200 employees and a strong management team. The business model of Castle Biosciences is based on the development and marketing of personalized medical tests that can help improve the diagnosis and treatment of cancer patients. Castle Biosciences primarily offers its tests through doctors and medical facilities. The company specializes in the development of prognostic and predictive tests that can provide doctors with important information to create personalized treatment plans for their patients. Castle Biosciences has several divisions specializing in different types of cancer. One of the most important divisions is in the field of dermatology, developing and distributing tests for the diagnosis and prognosis of melanoma and other skin cancer types. Castle Biosciences also offers personalized tests for cancer of the eyes, stomach, and lung. Another important product of Castle Biosciences is the DecisionDx-Melanoma test. The test is a molecular diagnostic procedure that predicts the likelihood of melanoma recurrence. The test utilizes proprietary gene expression analysis to assess the risk of melanoma recurrence within five years after tumor removal. The results of the test can help minimize the risk of relapse and improve the patients' quality of life. Castle Biosciences has also developed the DecisionDx-UM test, a diagnostic test for uveal melanoma, a rare cancer affecting the eyes. The DecisionDx-UM test uses RNA expression to predict the individual metastatic risk of the cancer and support optimal medical management. The company has also specialized in the development of tests for gastric cancer. The CastleTest™ analyzes the transcription activity of 11 genes to determine the risk of tumor spread from the primary gastric location. Castle Biosciences has made significant progress in recent years and continues to expand through the introduction of new products and services in the market. The company emphasizes a certification program and continuous training of doctors and pathologists to support test performance. Additionally, Castle Biosciences has brought together additional knowledge and expertise through partnerships with other companies and institutions to develop innovative solutions for a wider range of cancer types. Overall, Castle Biosciences is a company specializing in innovative solutions for the diagnosis and prognosis of cancer. The personalized tests from Castle Biosciences have the potential to improve the quality of life for cancer patients by providing additional information for individual treatment plans. With its dedicated workforce and successful products, Castle Biosciences will continue to play an important role in the fight against cancer.

Castle Biosciences SWOT Analysis

Strengths

Castle Biosciences Inc is a prominent player in the biotechnology industry, known for their innovative products and services.

The company has a strong portfolio of advanced diagnostic tests for skin cancer and other dermatologic conditions, offering reliable and accurate results.

Castle Biosciences Inc has established a solid reputation for their expertise and comprehensive understanding of personalized medicine, which further enhances their market position.

The company's dedicated and skilled team of professionals is a key strength, ensuring high-quality research, development, and customer support.

Weaknesses

One potential weakness for Castle Biosciences Inc is their reliance on a limited range of diagnostic tests. Diversifying their product offerings could help mitigate this risk.

The company may face challenges in terms of regulatory compliance and obtaining necessary approvals for their diagnostic tests, which could result in delays or limitations on market entry.

Castle Biosciences Inc may also be more vulnerable to competition from larger, established biotechnology companies that have greater resources and market presence.

Opportunities

There is a growing demand for personalized medicine and advanced diagnostics, presenting significant opportunities for Castle Biosciences Inc to expand their market share.

The company can explore collaborations and partnerships with healthcare providers and pharmaceutical companies to leverage their expertise and reach a wider customer base.

Expanding into international markets could also be a viable opportunity for Castle Biosciences Inc to broaden their customer reach and increase revenue.

Threats

Competition in the biotechnology industry is intense, with new entrants and established players constantly emerging. Castle Biosciences Inc must stay vigilant and continuously innovate to stay ahead.

Evolving healthcare regulations and policies can pose challenges for Castle Biosciences Inc, as compliance and adherence to these regulations may require significant resources and adaptations.

Market uncertainties and economic fluctuations can also impact the demand for diagnostic tests, making it essential for Castle Biosciences Inc to maintain financial stability and diversify revenue streams.

Castle Biosciences Employees

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  • Max

Castle Biosciences Employees
Details
Date
Castle Biosciences Employees
Jan 1, 2019
- Employees
Jan 1, 2020
- Employees
Jan 1, 2021
- Employees
Jan 1, 2022
- Employees
Jan 1, 2023
- Employees
Jan 1, 2024
- Employees
Jan 1, 2025
- Employees

Castle Biosciences Segments

Castle Biosciences Revenue by Segment (1/2)

  • Max

Dermatologic
Non Dermatologic
Details
Date
Dermatologic
Non Dermatologic
Other
Jan 1, 2025
216.37 M USD
127.86 M USD
0.00 USD

Castle Biosciences Revenue by Segment (2/2)

  • Max

Reportable Segment
Details
Date
Reportable Segment
Jan 1, 2025
344.23 M USD

Castle Biosciences Eulerpool Fair Value

Details

Fair Value Estimate

ⓘ

What Is Fair Value?

Fair value is an estimate of what a stock is truly "worth" based on its financial fundamentals, independent of the current market price. If the calculated fair value is above the current share price, the stock may be undervalued — and vice versa. This chart shows three different fair value approaches so you can cross-check them against each other.

Earnings-Based Fair Value

Calculated by multiplying the current earnings per share (EPS) by the average historical P/E ratio over a selected multi-year period. The smoothing over several years filters out temporary spikes or dips. If this fair value exceeds the market price, it suggests the stock is cheap relative to its earning power.

Example: Fair Value (Earnings) 2022 = EPS 2022 × Average P/E 2019–2021

Revenue-Based Fair Value

Derived by multiplying revenue per share by the average historical price-to-sales ratio. This method is particularly useful for companies with volatile or temporarily depressed earnings, as revenue tends to be more stable than profits. It answers: "At what price has the market historically valued each dollar of this company's sales?"

Example: Fair Value (Revenue) 2022 = Revenue per Share 2022 × Average P/S 2019–2021

Dividend-Based Fair Value

Calculated by dividing the dividend per share by the average historical dividend yield. This approach is most relevant for mature, consistently dividend-paying companies. If the resulting fair value is higher than the current price, it implies the stock offers a better yield than its historical average.

Example: Fair Value (Dividend) 2022 = Dividend per Share 2022 ÷ Average Yield 2019–2021

How to Use This Chart

When all three fair value lines converge above the current price, it strengthens the case that the stock is undervalued. When they diverge, investigate why — it may indicate a structural shift in margins, payout policy, or growth rate. The forward estimates on the right extend the analysis using projected fundamentals, helping you assess whether the current price already reflects future growth expectations.

Castle Biosciences historical P/E ratio, EBIT multiple, and P/S ratio

Castle Biosciences annual returns

Details

Annual Return

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What This Chart Shows

This chart breaks down Castle Biosciences's total annual return into two components: price return (gains or losses from stock price movement) and dividend return (income received from dividend payments). Together, they represent the total return an investor would have earned in each calendar year.

Price Return

Price return measures the percentage change in Castle Biosciences's stock price from January 1st to December 31st of each year. Positive bars indicate the stock appreciated; negative bars show a decline. This is the component most investors focus on, but it tells only part of the story — especially for dividend-paying stocks.

Dividend Return

Dividend return represents the income generated from dividends paid during the year, expressed as a percentage of the starting stock price. While it may seem small in any single year (typically 1–4 % for established companies), dividends compound significantly over decades and have historically contributed roughly 40 % of total stock market returns.

What to Look For

Examine how many years showed positive vs. negative returns to gauge consistency. A stock with mostly positive years and small drawdowns suggests lower risk. Also compare Castle Biosciences's annual returns to a benchmark index — consistently outperforming the market is a hallmark of a strong investment. Pay attention to the worst years: understanding downside risk is just as important as chasing upside potential.

Castle Biosciences shares outstanding

The number of shares of Castle Biosciences was 29.33 M in 2025. This indicates how many shares Castle Biosciences is divided into. Since shareholders are the owners of a company, each share represents a small portion of the company's ownership.
  • 3 Years

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  • Max

Number of stocks
Details
Date
Number of stocks
Jan 1, 2021
25.33 M Stocks
Jan 1, 2022
26.40 M Stocks
Jan 1, 2023
27.14 M Stocks
Jan 1, 2024
30.20 M Stocks
Jan 1, 2025
29.33 M Stocks
Jan 1, 2026 (e)
29.33 M Stocks
Jan 1, 2027 (e)
29.33 M Stocks
Jan 1, 2028 (e)
29.33 M Stocks

Current Castle Biosciences forecasts and price targets in September 2026

Analyst Price Targets 2026
Δ MOM Price Target
0.00 %
Buy
93.33 % (14)
Hold
6.67 % (1)
Sell
0.00 % (0)
12M Price Target
40.00
Last Price
35.81
Currency
USD
12M Return Potential
11.70 %
LTM Return
60.15 %

Castle Biosciences Analyst Rating Actions

DateFirmActionRatingReliability
8/3/2026
BTIG
BTIG
MaintainedBuy49
5/13/2026
BTIG
BTIG
MaintainedBuy49
5/7/2026
Baird
Baird
MaintainedOutperform65
4/20/2026
Canaccord Genuity
Canaccord Genuity
MaintainedBuy63
2/27/2026
Baird
Baird
MaintainedOutperform65
1/26/2026
Guggenheim
Guggenheim
MaintainedBuy39
1/12/2026
Lake Street
Lake Street
MaintainedBuy–
1/5/2026
Guggenheim
Guggenheim
MaintainedBuy39
12/22/2025
Canaccord Genuity
Canaccord Genuity
MaintainedBuy63
12/12/2025
BTIG
BTIG
MaintainedBuy49

Eulerpool Reliability Score (0–100): measures how often a firm’s bullish or bearish calls were directionally correct three months later, blended with the average return following its calls. Every rating we record is stored permanently and scores update continuously; firms with fewer than 3 measured calls are not scored yet.

Castle Biosciences Earnings Estimates & Surprises

DateEPS estimateEPS ActualRevenue EstimatePrice reactionQuarterly report
11/2/2026-0.38USD-92.26 MUSD-2026 Q3
7/30/2026-0.41USD-0.07USD86.23 MUSD-2026 Q2
5/6/2026-0.49USD-0.49USD79.23 MUSD-2026 Q1
2/26/2026-0.23USD-0.08USD79.89 MUSD-2025 Q4
11/3/2025-0.34USD-0.02USD80.38 MUSD-2025 Q3
8/4/2025-0.51USD0.15USD68.00 MUSD-2025 Q2
5/5/2025-0.08USD-0.90USD80.31 MUSD-2025 Q1
2/27/2025-0.04USD0.32USD83.89 MUSD-2024 Q4
11/4/2024-0.06USD0.08USD80.58 MUSD-2024 Q3
8/5/2024-0.27USD0.31USD69.34 MUSD-2024 Q2

EESG©

Eulerpool ESG Scorecard© for the Castle Biosciences stock

38/100
2
Environment
41
Social
72
Governance
E

Environment

Scope 1 - Direct Emissions—
Scope 2 - Indirect emissions from purchased energy—
Scope 3 - Indirect emissions within the value chain—
Total CO₂ emissions—
CO₂ reduction strategy
Coal energy
Nuclear power
Animal experiments
Fur & Leather—
Pesticides—
Palm Oil—
Tobacco
Genetically modified organisms
Climate concept—
Sustainable forestry—
Recycling regulations
Environmentally friendly packaging
Hazardous substances
Fuel consumption and efficiency
Water consumption and efficiency
S

Social

Percentage of female employees64
Percentage of women in management—
Percentage of Asian employees6
Share of Asian management—
Percentage of Hispanic/Latino employees21
Hispano/Latino Management share—
Percentage of Black employees3
Black Management Share—
Percentage of white employees65
White Management Share—
Adult content
Alcohol
Weapons—
Firearms
Gambling
Military contracts
Human rights concept
Privacy concept—
Occupational health and safety
Catholic
G

Governance (Corporate Governance)

Environmental reporting
Stakeholder Engagement
Call Back Policies
Antitrust law

The Eulerpool ESG Scorecard© is the strictly copyrighted intellectual property of Eulerpool Research Systems. Any unauthorized use, imitation, or infringement will be actively pursued and may lead to significant legal consequences. For licenses, collaborations, or usage rights, please contact us directly via our contact form. Contact Form to us.

Castle Biosciences shareholder structure

% Name
10.21907%
BLACKROCK, INC.
BLACKROCK, INC.
9.44959%
RTW INVESTMENTS, LP
RTW INVESTMENTS, LP
6.06330%
PRINCIPAL FINANCIAL GROUP INC
PRINCIPAL FINANCIAL GROUP INC
4.62584%
PORTOLAN CAPITAL MANAGEMENT, LLC
PORTOLAN CAPITAL MANAGEMENT, LLC
4.03399%
VANGUARD CAPITAL MANAGEMENT LLC
VANGUARD CAPITAL MANAGEMENT LLC
3.56205%
DIMENSIONAL FUND ADVISORS LP
DIMENSIONAL FUND ADVISORS LP
...

Castle Biosciences Beneficial Ownership Filings (SEC 13D/G)

Free Float
88.4%
Float Shares
26.99 M
Shares Outstanding
30.55 M
StakeHolderFiling
12.30%
Wasatch Advisors, Inc. 87-0319391
Wasatch Advisors, Inc. 87-0319391
SEC ↗
10.44%
ARK Investment Management LLC
ARK Investment Management LLC
SEC ↗
9.30%
RTW Investments, LP
RTW Investments, LP
SEC ↗
8.20%
BlackRock, Inc.
BlackRock, Inc.
SEC ↗
8.05%
S
S
SEC ↗
7.30%
Johan D. Swildens
Johan D. Swildens
SEC ↗
7.10%
(1) BlackRock, Inc.
(1) BlackRock, Inc.
SEC ↗
6.62%
Derek J. Maetzold
Derek J. Maetzold
SEC ↗
6.00%
Sofinnova HealthQuest Partners, L.P. (“HealthQuest”)
Sofinnova HealthQuest Partners, L.P. (“HealthQuest”)
SEC ↗
6.00%
HealthQuest Venture Management, L.L.C. (“HealthQuest Management”)
HealthQuest Venture Management, L.L.C. (“HealthQuest Management”)
SEC ↗

Castle Biosciences Executives and Management Board

11 members · avg. age 62 · 36 % women

DM

Mr. Derek Maetzold (63)

President, Chief Executive Officer, Founder, Director · since 2007

6.94 M USD

Management

KO

Ms. Kristen Oelschlager (57)

Chief Operating Officer

2.45 M USD
TJ

Mr. Tobin Juvenal (65)

Chief Commercial Officer

2.45 M USD
FS

Mr. Frank Stokes (55)

Chief Financial Officer

2.31 M USD

Board of Directors

RC

Mr. Rodney Cotton (65)

Independent Director

549,999.00 USD
TO

Ms. Tiffany Olson (65)

Independent Director

319,683.00 USD
DB

Mr. Daniel Bradbury (64)

Independent Chairman of the Board

297,147.00 USD
GC

Mr. G. Bradley Cole (69)

Independent Director

279,647.00 USD
MH

Mr. Miles Harrison (60)

Independent Director

277,147.00 USD
KC

Ms. Kimberlee Caple (63)

Independent Director

267,147.00 USD

Frequently asked questions about Castle Biosciences

The business model of Castle Biosciences Inc revolves around providing diagnostic and prognostic solutions for patients with skin and other cancers. By leveraging advanced genomic technology, the company offers diagnostic tests that assess the risk, recurrence, and progression of various cancers. Castle Biosciences focuses on developing and commercializing molecular diagnostic tests that aid in personalized treatment decisions for cancer patients. With a patient-centric approach, the company aims to improve patient outcomes and contribute to the advancement of precision medicine. Castle Biosciences Inc is dedicated to revolutionizing cancer management through innovative diagnostics.

Castle Biosciences Inc is primarily active in the healthcare industry, specifically in the field of precision medicine. The company specializes in developing and commercializing molecular diagnostics tests that provide personalized genomic information to aid in the diagnosis and treatment of various types of cancer. Castle Biosciences Inc's innovative solutions help healthcare professionals make informed decisions about patient care by assessing the likelihood of disease recurrence and determining optimal treatment plans. With a focus on improving patient outcomes, Castle Biosciences Inc is dedicated to advancing precision medicine in oncology.

The main competitors of Castle Biosciences Inc in the market are Myriad Genetics, Genomic Health, and NanoString Technologies.

Castle Biosciences Inc is a leading precision oncology company that specializes in molecular diagnostics. Established in 2008, the company is dedicated to providing personalized medicine solutions for patients with challenging cancers. With a focus on dermatologic cancers, Castle Biosciences utilizes advanced genomic and proteomic technology to develop innovative diagnostic tests. Their flagship product, DecisionDx-Melanoma, is a powerful tool that assesses the risk and prognosis of melanoma patients. Castle Biosciences Inc has a strong commitment to research, collaboration, and improving patient outcomes. With their cutting-edge technology and expertise, the company continues to revolutionize cancer diagnostics and treatment strategies.

Castle Biosciences Inc has achieved several significant milestones since its inception. The company pioneered the development of DecisionDx®-Melanoma, a groundbreaking gene expression profile test, which has revolutionized the management of melanoma patients. Castle Biosciences Inc has also expanded its product portfolio with DecisionDx®-UM, a test for uveal melanoma, providing accurate prognostic information for physicians and patients. In addition, the company has received numerous awards and recognitions for its innovative approach to personalized medicine, further establishing its leadership in the field. Castle Biosciences Inc continues to drive advancements in genomic diagnostics, improving patient outcomes and transforming cancer care.

Castle Biosciences Inc is primarily present in the United States.

Castle Biosciences Inc represents values such as innovation, accuracy, and patient-centricity. With a strong corporate philosophy centered around precision medicine, the company utilizes advanced genomic technology to provide actionable, personalized information to aid healthcare decisions for patients with underserved cancers. Castle Biosciences Inc is committed to improving patient outcomes through its proprietary diagnostic tests that offer valuable insights into the individual biology of each patient. By combining science, research, and a patient-first approach, Castle Biosciences Inc strives to empower healthcare providers and patients with the necessary tools to make informed, targeted treatment decisions.

Analysts currently set an average price target of 39.00 USD for the Castle Biosciences stock (median: 40.00 USD), implying +8.9 % versus the latest price. The consensus is based on 15 analyst ratings.

15 analysts currently rate the Castle Biosciences stock: 14 recommend buying, 1 holding and 0 selling. For 2026, analysts expect Castle Biosciences to generate revenue of 372.59 M USD and earnings per share of -1.27 USD.

Converted at the current exchange rate, the Castle Biosciences share trades at 31.42 EUR (35.81 USD).

The Castle Biosciences share (CSTL) is listed on 1 stock exchanges, including: NASDAQ (CSTL).

Castle Biosciences Inc is a biotechnology company that develops and distributes diagnostic tests and genetic analyses. The company is headquartered in Friendswood, Texas, USA and has been operating in the industry since 2007. The main task of Castle Biosciences is to develop clinically accurate prediction tools to assess the progression of tumors and consider them in patient treatment. For this purpose, the company has developed a range of test procedures based on a combination of genotyping, proteomics, and immuno-sensing methods. The key product of Castle Biosciences is the Prognostic Test, which provides an accurate assessment of the risk of skin cancer. The test uses molecular markers to predict the risk of melanoma or ocular melanoma and determine if therapy is necessary. Another product is DecisionDx-UM, a powerful diagnostic assay that aids in the prognosis of malignant uveal melanoma (UM). In combination with standardized clinical factors such as age, gender, and tumor size, DecisionDx-UM is an important indicator of disease progression as well as promising treatment approaches. Castle Biosciences offers a wide range of proteomic analyses tailored to the needs of the patient. These tests are used to estimate the risk of cancer and enable treating physicians to develop treatment and follow-up strategies. The company also conducts a number of research and development initiatives aimed at understanding the molecular basis of cancer and developing novel diagnostic tests and therapies. The goal is to make groundbreaking scientific discoveries to identify new and improved molecular markers that can be used to assess disease progression and the efficacy of therapies. Overall, Castle Biosciences provides an advanced and accurate platform for cancer diagnostics that can help patients and doctors make better-informed decisions. The company is dedicated to further exploring the molecular basis of cancer and developing more innovative diagnostic tools to improve patient care worldwide. In summary, the business model of Castle Biosciences is focused on the development and marketing of diagnostic tools for cancer treatment. The company offers a wide range of molecular, proteomic, and immuno-sensing analyses that enable accurate prognosis of tumor progression. The company also conducts extensive research and development initiatives to discover new molecular markers for the diagnosis and treatment of cancer.

The expected revenue of Castle Biosciences is 372.59 M USD. This figure is based on current financial data and reflects the company's business performance.

The expected profit of Castle Biosciences is -37.14 M USD. The net profit reflects the company's profitability after deducting all expenses.

The price-to-earnings ratio (P/E) of Castle Biosciences is currently -28.29. The P/E ratio compares the current share price to the earnings per share and helps investors assess the valuation of the Castle Biosciences stock.

The price-to-sales ratio (P/S) of Castle Biosciences is currently 2.82. The P/S ratio compares the market capitalization to the annual revenue and serves as a valuation metric for the Castle Biosciences stock.

The Eulerpool Quality Score for Castle Biosciences is 2/10.

The ISIN of Castle Biosciences is US14843C1053. The ISIN (International Securities Identification Number) is a globally unique identifier for securities.

The WKN of Castle Biosciences is A2PNH3. The WKN (Wertpapierkennnummer) is a six-digit German security identification number.

The ticker of Castle Biosciences is CSTL. The ticker symbol is used to trade Castle Biosciences shares on the stock exchange.

Castle Biosciences paid dividends every year for the past 0 years.

Castle Biosciences is assigned to the 'Health' sector.

The dividends of Castle Biosciences are distributed in USD.

Fair ValueTerminal
31.87 USD
Over-/UndervaluationTerminal
Fairly valued
Sector
Industry
Health Care Providers & Services
Number of shares
Employees
Revenue per Employee
389,742.92 USD
Revenue growth Ø5 years
EBIT growth Ø5 years
Net Income growth Ø5 years
Currency
USD
Initial public offering
Jul 25, 2019
ISIN
US14843C1053
Cusip
14843C105
Sedol
BKLCWZ3
Market capitalization
1.05 B USDSmall Cap
52-Week Range
18.15–43.04USD
Revenue growth (10Y) > 5%
Revenue growth (3Y) > 5 %
EBIT growth (10Y) > 5%
EBIT growth (3Y) > 5 %
Net debt < 4x EBIT
Profitable since 10Y+
EBIT Drawdown (10Y) < 50%
Return on Equity (ROE) > 15%
ROCE > 15%
Return Expectation > 10%
PEG
—
P/E ratio
P/Ee 2026
-28.29
P/Ee 2027
-36.39
P/Ee 2028
-99.41
P/Ee 2029
68.21
P/Ee 2030
35.99
P/S
P/Se
2.82
EV/EBIT
—
P/B Ratio
2.22
ROE (Return on Equity)
ROA (Return on Assets)
ROCE (Return on Capital Employed)
ROIC (Return on Invested Capital)
-5.01 %
Gross Margin
79.39 %
EBIT Margin
-12.44 %
Net Margin
-7.02 %
EPS (Earnings Per Share)
-0.82 USD
Net Debt / EBIT
2.46
Debt/Equity
0.02
Last updated Sep 27, 2026, 5:33 AM

Castle Biosciences Ticker

NASDAQ · CSTL

Castle Biosciences FIGI

CSTL:US · BBG006YWVSR3CSTL:UA · BBG00PKS73F0CSTL:UC · BBG00PKS73G9CSTL:UN · BBG00PKS73J6CSTL:UP · BBG00PKS73K4CSTL:UQ · BBG00PKS73L3CSTL:UB · BBG00PKS73M2CSTL:UM · BBG00PKS73P9CSTL:UX · BBG00PKS73Q8CSTL:UD · BBG00PKS73W1CSTL:UF · BBG00PKS73Z8CSTL:VY · BBG00PKS7404