Annexon (ANNX) Stock Price

Annexon Price

NASDAQ·CLOSED
5.30USD+0.07 (+1.33 %)
Market closed

Analysts set a median price target of 14.28 USD, implying 169.4% above the current price. Of 16 analysts, 15 rate the stock a buy — an overall Buy consensus. The stock trades about 159% above its 52-week low.

Annexon stock price

Volume
Details

Stock Price

How to Read This Chart

This chart tracks the historical stock price of Annexon over time. You can switch between daily, weekly, and monthly views and select custom time ranges — from a single day to the full available history. Use the toggle to view price changes in absolute currency terms or as a percentage change relative to the starting date.

Total Return vs. Price Return

The "Total Return" toggle includes reinvested dividends on top of the pure price movement. This is critical because dividends can account for a significant portion of long-term returns. Historically, roughly 40 % of the S&P 500's total return has come from dividends. Always compare total return when evaluating a stock's real performance against a benchmark.

Intraday Price Data

When viewing a one-day time frame, the chart displays real-time intraday price movements. This is useful for observing how Annexon stock reacts to market openings, earnings releases, or breaking news throughout the trading session.

What to Look For

Look for long-term trends (sustained upward or downward movements over months and years), support and resistance levels (price zones where the stock repeatedly bounces or reverses), and volatility (how much the price fluctuates day to day). Comparing Annexon's price chart to a market index like the S&P 500 can reveal whether the stock is outperforming or underperforming the broader market.

Annexon Stock Price History
DateAnnexon Price
7/23/20265.30 USD
7/22/20265.23 USD
7/21/20265.39 USD
7/20/20265.57 USD
7/17/20265.80 USD
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6/18/20264.86 USD
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6/12/20264.68 USD
6/11/20264.78 USD
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5/28/20265.49 USD
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5/20/20264.99 USD
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5/11/20265.68 USD
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5/1/20265.75 USD
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4/29/20265.89 USD
4/28/20266.00 USD
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3/31/20265.54 USD
3/30/20264.96 USD
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2/24/20264.96 USD
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2/11/20265.24 USD
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2/6/20265.73 USD
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2/2/20266.38 USD
1/30/20266.24 USD
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1/27/20266.57 USD
1/26/20266.66 USD
1/23/20266.78 USD
1/22/20266.96 USD
1/21/20266.85 USD
1/20/20266.16 USD
1/16/20266.07 USD
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1/14/20266.68 USD
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1/2/20264.69 USD
12/31/20255.02 USD
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11/21/20254.27 USD
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10/31/20253.16 USD
10/30/20252.93 USD
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10/28/20253.45 USD
10/27/20253.54 USD
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10/22/20253.00 USD
10/21/20253.13 USD
10/20/20253.16 USD
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10/9/20253.26 USD
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10/6/20253.18 USD
10/3/20253.19 USD
10/2/20253.11 USD
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9/26/20253.37 USD
9/25/20252.79 USD
9/24/20252.82 USD
9/23/20252.91 USD
9/22/20252.98 USD
9/19/20252.86 USD
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9/5/20252.17 USD
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9/2/20252.07 USD
8/29/20252.06 USD
8/28/20252.12 USD
8/27/20252.11 USD
8/26/20252.15 USD
8/25/20252.15 USD
8/22/20252.31 USD
8/21/20252.17 USD
8/20/20252.14 USD
8/19/20252.19 USD
8/18/20252.35 USD
8/15/20252.44 USD
8/14/20252.38 USD
8/13/20252.60 USD
8/12/20252.44 USD
8/11/20252.35 USD
8/8/20252.36 USD
8/7/20252.37 USD
8/6/20252.35 USD
8/5/20252.48 USD
8/4/20252.53 USD
8/1/20252.45 USD
7/31/20252.40 USD
7/30/20252.59 USD
7/29/20252.38 USD
7/28/20252.49 USD
Access this data via the Eulerpool API

Annexon Revenue, EBIT, Net Income

  • 3 Years

  • 5 Years

  • 10 Years

  • 25 Years

  • Max

Revenue
EBIT
Net Income
Details
Date
Revenue
EBIT
Net Income
Jan 1, 2020
0.00 USD
-63.47 M USD
-62.75 M USD
Jan 1, 2021
0.00 USD
-130.71 M USD
-127.79 M USD
Jan 1, 2022
0.00 USD
-145.60 M USD
-138.30 M USD
Jan 1, 2023
0.00 USD
-143.72 M USD
-134.24 M USD
Jan 1, 2024
0.00 USD
-154.07 M USD
-138.20 M USD
Jan 1, 2025
0.00 USD
-216.41 M USD
-206.69 M USD
Jan 1, 2026 (e)
0.00 USD
-208.31 M USD
-141.54 M USD
Jan 1, 2027 (e)
37.83 M USD
-182.81 M USD
-138.97 M USD

Annexon Income Statement, Balance Sheet, Cash Flow Statement

Last updated Jul 26, 2026, 7:06 PM
 
REVENUEM USD
GROSS MARGIN%
GROSS INCOMEM USD
EBITM USD
EBIT MARGIN%
NET INCOMEM USD
NET INCOME GROWTH%
SHARESM
2017201820192020202120222023202420252026e2027e
37.00
-8.11
-3.00-3.00-3.00-3.00-3.00-3.00-3.00-3.00-3.00-3.00-3.00
-20.00-19.00-32.00-63.00-130.00-145.00-143.00-154.00-216.00-208.00-182.00
-491.89
-18.00-18.00-37.00-62.00-127.00-138.00-134.00-138.00-206.00-141.00-138.00
105.5667.57104.848.66-2.902.9949.28-31.55-2.13
155.110.4313.1238.1638.4872.3778.22147.81155.11155.11155.11
Details

Income Statement Key Figures

Revenue and Revenue Growth

Revenue is the starting point of every income statement — it measures the total sales Annexon generates from its core business. Revenue growth (expressed as year-over-year percentage change) is one of the most important indicators of business momentum. Sustained growth above 10 % annually is generally considered strong, while declining revenue is a serious warning sign that demands investigation.

Gross Margin

Gross margin = (Revenue − Cost of Goods Sold) ÷ Revenue. It reveals what percentage of each dollar of revenue Annexon retains after direct production costs. High gross margins (above 50 %) are typical of asset-light businesses like software and brands, while capital-intensive industries like manufacturing often operate below 30 %. Compare Annexon's gross margin to industry peers and track it over time to spot improving or deteriorating pricing power.

EBIT and EBIT Margin

EBIT measures operating profit — what remains after subtracting all operating expenses (including R&D, sales, and administrative costs) from gross profit. The EBIT margin shows this as a percentage of revenue. Because it excludes interest and taxes, EBIT allows fair comparisons between companies with different debt levels and tax jurisdictions. A rising EBIT margin indicates improving operational efficiency.

Net Income and Earnings Per Share (EPS)

Net income is the company's final profit after all expenses, interest, and taxes. Dividing net income by the number of shares outstanding gives you EPS — the single most influential metric in stock valuation. Consistent EPS growth is the primary driver of long-term stock price appreciation. Always check whether EPS growth comes from genuine profit improvement or from share buybacks reducing the share count.

Shares Outstanding

The total number of shares Annexon has issued. A declining share count (through buybacks) boosts EPS and signals management confidence. A rising share count (through stock issuance) dilutes existing shareholders. Always monitor this number alongside EPS to get the full picture of per-share value creation.

Analyst Estimates

The projected figures represent consensus estimates from professional analysts. Compare these forecasts against Annexon's historical growth rates to assess whether expectations are realistic. A company that consistently beats consensus estimates tends to see its stock price rewarded over time, while repeated misses erode investor confidence.

Annexon stock margins

The Annexon margin analysis displays the gross margin, EBIT margin, as well as the profit margin of Annexon. The EBIT margin (EBIT/sales) indicates the percentage of sales that remains as operating profit. The profit margin shows the percentage of sales that remains for Annexon.
  • 3 Years

  • 5 Years

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  • 25 Years

  • Max

Gross margin
EBIT margin
Profit margin
Details
Date
Gross margin
EBIT margin
Profit margin
Jan 1, 2020
0.00 %
- %
- %
Jan 1, 2021
0.00 %
- %
- %
Jan 1, 2022
0.00 %
- %
- %
Jan 1, 2023
0.00 %
- %
- %
Jan 1, 2024
0.00 %
- %
- %
Jan 1, 2025
0.00 %
- %
- %
Jan 1, 2026 (e)
0.00 %
- %
- %
Jan 1, 2027 (e)
0.00 %
-483.26 %
-367.38 %

Annexon Stock Revenue, EBIT, Earnings per Share

The Annexon earnings per share therefore indicates how much revenue Annexon has generated per share in a given period. The earnings before interest and taxes per share shows how much of the operating profit corresponds to each share. The earnings per share indicates how much of the profit belongs to each share.
  • 3 Years

  • 5 Years

  • 10 Years

  • 25 Years

  • Max

Revenue per Share
EBIT per share
Earnings per Share
Details
Date
Revenue per Share
EBIT per share
Earnings per Share
Jan 1, 2020
0.00 USD
-1.66 USD
-1.64 USD
Jan 1, 2021
0.00 USD
-3.40 USD
-3.32 USD
Jan 1, 2022
0.00 USD
-2.01 USD
-1.91 USD
Jan 1, 2023
0.00 USD
-1.84 USD
-1.72 USD
Jan 1, 2024
0.00 USD
-1.04 USD
-0.93 USD
Jan 1, 2025
0.00 USD
-1.40 USD
-1.33 USD
Jan 1, 2026 (e)
0.00 USD
-1.34 USD
-0.98 USD
Jan 1, 2027 (e)
0.26 USD
-1.18 USD
-0.96 USD

Annexon business model & stock analysis

Annexon Inc is a biopharmaceutical company based in South San Francisco, California. It was founded in 2011 by Doug Love, Ted Love, and Arnon Rosenthal, who had previously worked at major pharmaceutical companies such as Genentech and Novartis. The company's main goal is to develop new treatment options for neurodegenerative diseases, focusing on the development of drugs that target the autophagy process in cells to reduce damage to nerve cells and alleviate symptoms. Annexon Inc has two divisions, Annexon Biosciences and Annexon Clinical, with partnerships with renowned pharmaceutical companies to advance drug development. Its main product is ANX005, a therapeutic antibody protein that targets the role of the complement system in neurodegenerative diseases. Annexon Inc has received multiple awards for its work and innovations and has a dedicated team of scientists and executives committed to improving the lives of people with neurodegenerative diseases.

Annexon SWOT Analysis

Strengths

  • Annexon Inc is a leading biopharmaceutical company specialized in the development of novel therapeutics for autoimmune and neurodegenerative diseases.
  • The company possesses a strong and diverse portfolio of potential drug candidates, which provides multiple revenue streams and growth opportunities.
  • Annexon Inc benefits from a highly skilled and experienced team of researchers, scientists, and executives, enabling efficient drug discovery, development, and commercialization.

Weaknesses

  • Annexon Inc relies heavily on external funding, which may pose challenges in maintaining financial stability and limiting control over strategic decisions.
  • The company's success is closely tied to the outcomes of clinical trials, which introduces inherent risks and uncertainties throughout the drug development process.

Opportunities

  • The increasing prevalence of autoimmune and neurodegenerative diseases presents a significant market opportunity for Annexon Inc's innovative therapeutics.
  • Collaborating with strategic partners or licensing agreements can accelerate the development and commercialization of Annexon Inc's drug candidates, expanding their market reach.
  • Continuous advancements in technology and scientific research provide Annexon Inc with the opportunity to discover and develop new treatment options for unmet medical needs.

Threats

  • The highly competitive pharmaceutical industry poses a threat to Annexon Inc's ability to secure a significant market share and successfully compete against established players.
  • Regulatory and legal complexities can arise during the drug development and approval processes, potentially impacting Annexon Inc's timelines and market access.
  • Economic downturns or shifts in healthcare policies and reimbursement systems may affect the affordability and demand for Annexon Inc's therapeutics.

Annexon Eulerpool Fair Value

Details

Fair Value Estimate

What Is Fair Value?

Fair value is an estimate of what a stock is truly "worth" based on its financial fundamentals, independent of the current market price. If the calculated fair value is above the current share price, the stock may be undervalued — and vice versa. This chart shows three different fair value approaches so you can cross-check them against each other.

Earnings-Based Fair Value

Calculated by multiplying the current earnings per share (EPS) by the average historical P/E ratio over a selected multi-year period. The smoothing over several years filters out temporary spikes or dips. If this fair value exceeds the market price, it suggests the stock is cheap relative to its earning power.

Example: Fair Value (Earnings) 2022 = EPS 2022 × Average P/E 2019–2021

Revenue-Based Fair Value

Derived by multiplying revenue per share by the average historical price-to-sales ratio. This method is particularly useful for companies with volatile or temporarily depressed earnings, as revenue tends to be more stable than profits. It answers: "At what price has the market historically valued each dollar of this company's sales?"

Example: Fair Value (Revenue) 2022 = Revenue per Share 2022 × Average P/S 2019–2021

Dividend-Based Fair Value

Calculated by dividing the dividend per share by the average historical dividend yield. This approach is most relevant for mature, consistently dividend-paying companies. If the resulting fair value is higher than the current price, it implies the stock offers a better yield than its historical average.

Example: Fair Value (Dividend) 2022 = Dividend per Share 2022 ÷ Average Yield 2019–2021

How to Use This Chart

When all three fair value lines converge above the current price, it strengthens the case that the stock is undervalued. When they diverge, investigate why — it may indicate a structural shift in margins, payout policy, or growth rate. The forward estimates on the right extend the analysis using projected fundamentals, helping you assess whether the current price already reflects future growth expectations.

Annexon historical P/E ratio, EBIT multiple, and P/S ratio

Annexon annual returns

Details

Annual Return

What This Chart Shows

This chart breaks down 's total annual return into two components: price return (gains or losses from stock price movement) and dividend return (income received from dividend payments). Together, they represent the total return an investor would have earned in each calendar year.

Price Return

Price return measures the percentage change in 's stock price from January 1st to December 31st of each year. Positive bars indicate the stock appreciated; negative bars show a decline. This is the component most investors focus on, but it tells only part of the story — especially for dividend-paying stocks.

Dividend Return

Dividend return represents the income generated from dividends paid during the year, expressed as a percentage of the starting stock price. While it may seem small in any single year (typically 1–4 % for established companies), dividends compound significantly over decades and have historically contributed roughly 40 % of total stock market returns.

What to Look For

Examine how many years showed positive vs. negative returns to gauge consistency. A stock with mostly positive years and small drawdowns suggests lower risk. Also compare 's annual returns to a benchmark index — consistently outperforming the market is a hallmark of a strong investment. Pay attention to the worst years: understanding downside risk is just as important as chasing upside potential.

Annexon shares outstanding

The number of shares of Annexon was 155.11 M in 2025. This indicates how many shares Annexon is divided into. Since shareholders are the owners of a company, each share represents a small portion of the company's ownership.
  • 3 Years

  • 5 Years

  • 10 Years

  • 25 Years

  • Max

Number of stocks
Details
Date
Number of stocks
Jan 1, 2020
38.16 M Stocks
Jan 1, 2021
38.48 M Stocks
Jan 1, 2022
72.37 M Stocks
Jan 1, 2023
78.22 M Stocks
Jan 1, 2024
147.81 M Stocks
Jan 1, 2025
155.11 M Stocks
Jan 1, 2026 (e)
155.11 M Stocks
Jan 1, 2027 (e)
155.11 M Stocks

Current Annexon forecasts and price targets in July 2026

Analyst Price Targets 2026
Δ MOM Price Target
0.00 %
Buy93.75 % (15)
Hold6.25 % (1)
Sell0.00 % (0)
12M Price Target
14.28
Last Price
5.30
Currency
USD
12M Return Potential
169.43 %
LTM Return
0 %

Annexon Earnings Estimates

DateEPS estimateRevenue EstimateQuarterly report
5/18/2026-0.29USD0.00USD2026 Q1
5/11/2026-0.29USD0.00USD2026 Q1
3/9/2026-0.33USD0.00USD2025 Q4
3/2/2026-0.33USD0.00USD2025 Q4
8/11/2025-0.37USD0.00USD2025 Q2
11/18/2024-0.26USD0.00USD2024 Q3
11/11/2024-0.26USD0.00USD2024 Q3
5/6/2024-0.46USD0.00USD2024 Q1
3/4/2024-0.49USD0.00USD2023 Q4
8/7/2023-0.58USD0.00USD2023 Q2

EESG©

Eulerpool ESG Scorecard© for the Annexon stock

57/100
60
Environment
66
Social
44
Governance
E

Environment

20
Scope 1 - Direct Emissions
Scope 2 - Indirect emissions from purchased energy
Scope 3 - Indirect emissions within the value chain
Total CO₂ emissions
CO₂ reduction strategy
Coal energy
Nuclear power
Animal experiments
Fur & Leather
Pesticides
Palm Oil
Tobacco
Genetically modified organisms
Climate concept
Sustainable forestry
Recycling regulations
Environmentally friendly packaging
Hazardous substances
Fuel consumption and efficiency
Water consumption and efficiency
S

Social

20
Percentage of female employees
Percentage of women in management
Percentage of Asian employees
Share of Asian management
Percentage of Hispanic/Latino employees
Hispano/Latino Management share
Percentage of Black employees
Black Management Share
Percentage of white employees
White Management Share
Adult content
Alcohol
Weapons
Firearms
Gambling
Military contracts
Human rights concept
Privacy concept
Occupational health and safety
Catholic
G

Governance (Corporate Governance)

4
Environmental reporting
Stakeholder Engagement
Call Back Policies
Antitrust law

The Eulerpool ESG Scorecard© is the strictly copyrighted intellectual property of Eulerpool Research Systems. Any unauthorized use, imitation, or infringement will be actively pursued and may lead to significant legal consequences. For licenses, collaborations, or usage rights, please contact us directly via our contact form. Contact Form to us.

Annexon shareholder structure

% Name
6.95306%
Redmile Group, LLC
Redmile Group, LLC
6.73029%
Alerce Investment Management, L.P.
Alerce Investment Management, L.P.
6.31483%
BVF Partners L.P.
BVF Partners L.P.
5.70750%
BlackRock Institutional Trust Company, N.A.
BlackRock Institutional Trust Company, N.A.
5.36381%
The Vanguard Group, Inc.
The Vanguard Group, Inc.
4.61802%
Fidelity Management & Research Company LLC
Fidelity Management & Research Company LLC
...

Annexon Executives and Management Board

DL

Mr. Douglas Love

(57)

President, Chief Executive Officer, Director · since 2014

Compensation3.67 M USD
JD

Dr. Jamie Dananberg

(67)

Executive Vice President, Chief Medical Officer

Compensation1.56 M USD
TY

Dr. Ted Yednock

(67)

Executive Vice President, Chief Innovation Officer

Compensation1.56 M USD
JL

Ms. Jennifer Lew

(52)

Chief Financial Officer, Executive Vice President

Compensation1.44 M USD
MO

Mr. Michael Overdorf

(55)

Executive Vice President, Chief Business Officer

Compensation1.40 M USD

Annexon Supply Chain

Frequently asked questions about Annexon

The business model of Annexon Inc is focused on the development of therapeutics for patients with autoimmune disorders and complement-mediated diseases. Annexon leverages its expertise in the understanding of the classical complement pathway to develop targeted therapies that can modulate this immune system response. By specifically targeting dysfunctional components of the complement system, Annexon aims to restore homeostasis and provide novel treatment options for patients. Annexon's approach includes the development of monoclonal antibodies that can selectively inhibit key targets involved in complement-mediated diseases. Through their research and development efforts, Annexon Inc aims to improve the lives of patients suffering from autoimmune disorders and complement-mediated diseases.

All fundamentals and in-depth analysis of Annexon

Our stock analysis for Annexon stock includes important financial indicators such as revenue, profit, P/E ratio, P/S ratio, EBIT, as well as information on dividends. We also assess aspects such as stocks, market capitalization, debt, equity, and liabilities of Annexon. If you are looking for more detailed information on these topics, we offer comprehensive analyses on our subpages.