Apellis Pharmaceuticals (APLS) Stock Price

Apellis Pharmaceuticals Price

NASDAQ·CLOSED
41.03
​
Market closed

Revenue has compounded at 32.0% per year over the past 5 years to 1.00 B USD. Apellis Pharmaceuticals's net margin stands at 2.2%, up from -1,121.3% several years earlier. Analysts set a median price target of 32.13 USD, implying 21.7% below the current price. Of 28 analysts, 20 rate the stock a buy — an overall Buy consensus.

Apellis Pharmaceuticals stock price

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Apellis Pharmaceuticals business model & stock analysis

Apellis Pharmaceuticals was founded in 2009 and is headquartered in Waltham, Massachusetts, USA. The company is a biopharmaceutical company specializing in developing innovative therapies for serious diseases of the immune system and the eyes. The company's focus is on developing therapies for rare and difficult-to-treat diseases. Apellis relies on a cellular science platform based on the discovery of new biological mechanisms. In the field of ophthalmology, Apellis is developing therapies for rare retinal diseases such as geographic atrophy, a progressive disease that can lead to blindness. The company has developed a new drug called APL-2, which is currently being tested in clinical trials. APL-2 inhibits the complement system, an important component of the immune system that plays a crucial role in retinal diseases. In the field of immunology, Apellis is working on developing therapies for autoimmune diseases, where the immune system attacks the body's own tissues. One such disease is paroxysmal nocturnal hemoglobinuria (PNH), which can lead to destruction of red blood cells. Apellis has developed a drug called APL-2, which inhibits the complement system and stops the breakdown of red blood cells. APL-2 is also being investigated for other autoimmune diseases such as the rare blood disorder syndrome, thrombotic microangiopathy syndrome. Apellis is also developing a therapy for chronic obstructive pulmonary disease (COPD), which can cause survival problems in advanced stages. The research focus is on identifying targets in the complement system and developing therapeutics to inhibit these targets. Apellis' business model is based on a collaborative approach, working closely with patient support groups to better understand patient needs and develop a deep physiological understanding of disease mechanisms to explore more effective therapy approaches. Apellis also collaborates with biotechnology partners and suppliers to accelerate the development of its drugs and reduce costs. Apellis has a strong financing base and has conducted several successful investment rounds in recent years. In 2017, the company raised $150 million in a Series E investment round. In 2019, Apellis received a $250 million investment from Swiss Re, one of the world's largest reinsurance companies, for a 10% stake in the company. This investment provides Apellis with the financial stability necessary for accelerated drug development. In 2020, Apellis obtained approval for APL-2 for the treatment of paroxysmal nocturnal hemoglobinuria (PNH) in the EU. In the same year, the company also obtained accelerated approval for APL-2 for the treatment of synergenic constipation syndrome. In summary, Apellis Pharmaceuticals is an innovative biopharmaceutical company specializing in the development of therapies for rare and difficult-to-treat diseases of the immune system and the eyes. With a strong financing base and a wide range of products, the company is well positioned to fully leverage the potential of its cellular science platform and provide innovative treatment options for patients.

Frequently asked questions about Apellis Pharmaceuticals

The business model of Apellis Pharmaceuticals Inc is focused on developing and commercializing novel therapeutic compounds to treat a wide range of diseases. Apellis Pharmaceuticals utilizes a targeted approach, specifically focusing on complement-mediated diseases such as paroxysmal nocturnal hemoglobinuria (PNH) and geographic atrophy (GA) associated with age-related macular degeneration (AMD). By researching and developing innovative treatments, Apellis Pharmaceuticals aims to address unmet medical needs and improve patients' quality of life. Apellis Pharmaceuticals Inc is dedicated to advancing the field of medicine through its commitment to research, development, and commercialization of cutting-edge therapies.

Apellis Pharmaceuticals Inc is primarily active in the biotechnology and pharmaceutical industries.

The main competitors of Apellis Pharmaceuticals Inc in the market include pharmaceutical companies such as Alexion Pharmaceuticals, Inc., Biogen Inc., and Genentech, Inc. Other major competitors in the biopharmaceutical industry include Novartis AG, Bristol-Myers Squibb Company, and Regeneron Pharmaceuticals, Inc.

Apellis Pharmaceuticals Inc, founded in 2009, is a global biopharmaceutical company focused on developing novel therapeutic compounds for treating various diseases. Headquartered in Waltham, Massachusetts, Apellis specializes in developing targeted therapies to address unmet medical needs. The company prioritizes innovative approaches and leverages its proprietary technology platforms to develop transformative therapies for patients. Apellis Pharmaceuticals Inc has a rich history of advancing drug candidates, with a particular emphasis on complement immunotherapy. With a dedicated team of scientists and industry experts, Apellis Pharmaceuticals Inc aims to make a significant impact on healthcare by offering potentially life-changing treatment options for patients worldwide.

Apellis Pharmaceuticals Inc has achieved several significant milestones. In 2019, the company received approval from the U.S. FDA for its first drug, Empaveli, as a treatment for paroxysmal nocturnal hemoglobinuria (PNH). This milestone marked a major breakthrough in the treatment of this rare blood disorder. Apellis Pharmaceuticals also expanded its clinical pipeline, with ongoing research and development in various therapeutic areas, including age-related macular degeneration and autoimmune diseases. The company continues to drive innovation through its commitment to advancing novel therapies and improving patient outcomes.

Apellis Pharmaceuticals Inc is primarily present in the United States, with its headquarters located in Waltham, Massachusetts. The company operates globally and has a strong presence across various countries and regions. Apellis Pharmaceuticals Inc has expanded its reach to other regions as well, including Europe, Asia-Pacific, and other international markets. With a commitment to developing innovative therapies, Apellis Pharmaceuticals Inc aims to improve the lives of patients worldwide through its presence in multiple countries and regions.

Apellis Pharmaceuticals Inc represents a commitment to improving the lives of patients by developing innovative and targeted therapies. The company's core values include integrity, collaboration, and a patient-centric approach. Apellis is dedicated to advancing medical science through groundbreaking research and development. With a focus on addressing unmet medical needs, Apellis strives to create value for shareholders while prioritizing the well-being of patients. By driving forward a corporate philosophy centered on scientific excellence and ethical practices, Apellis Pharmaceuticals Inc aims to make a positive impact in the healthcare industry.

Analysts currently set an average price target of 34.83 USD for the Apellis Pharmaceuticals stock (median: 32.13 USD), implying -15.1 % versus the latest price. The consensus is based on 28 analyst ratings.

28 analysts currently rate the Apellis Pharmaceuticals stock: 20 recommend buying, 7 holding and 1 selling. For 2026, analysts expect Apellis Pharmaceuticals to generate revenue of 871.41 M USD and earnings per share of -1.03 USD.

Converted at the current exchange rate, the Apellis Pharmaceuticals share trades at 36.82 EUR (41.03 USD).

The Apellis Pharmaceuticals share (APLS) is listed on 4 stock exchanges, including: NASDAQ (APLS), Frankfurt (1JK.F), München (1JK.MU), Düsseldorf (1JK.DU).

Apellis Pharmaceuticals Inc is an emerging biotechnology company focused on the development and commercialization of innovative therapies for rare medical needs. The business model of Apellis Pharmaceuticals is based on four core areas: research and development, clinical development, marketing, and business development.

The expected revenue of Apellis Pharmaceuticals is 871.41 M USD. This figure is based on current financial data and reflects the company's business performance.

The expected profit of Apellis Pharmaceuticals is -130.02 M USD. The net profit reflects the company's profitability after deducting all expenses.

The price-to-earnings ratio (P/E) of Apellis Pharmaceuticals is currently -39.77. The P/E ratio compares the current share price to the earnings per share and helps investors assess the valuation of the Apellis Pharmaceuticals stock.

The price-to-sales ratio (P/S) of Apellis Pharmaceuticals is currently 5.93. The P/S ratio compares the market capitalization to the annual revenue and serves as a valuation metric for the Apellis Pharmaceuticals stock.

The Eulerpool Quality Score for Apellis Pharmaceuticals is 6/10.

The ISIN of Apellis Pharmaceuticals is US03753U1060. The ISIN (International Securities Identification Number) is a globally unique identifier for securities.

The WKN of Apellis Pharmaceuticals is A2JAAW. The WKN (Wertpapierkennnummer) is a six-digit German security identification number.

The ticker of Apellis Pharmaceuticals is APLS. The ticker symbol is used to trade Apellis Pharmaceuticals shares on the stock exchange.

Fair ValueTerminal
34.05 USD
Over-/UndervaluationTerminal
Fairly valued
Sector
Industry
Biotechnology
Number of shares
Employees
Revenue per Employee
1.37 M USD
Revenue growth Ø5 years
EBIT growth Ø5 years
Net Income growth Ø5 years
Website apellis.com
Currency
USD
Initial public offering
Nov 9, 2017
ISIN
US03753U1060
Cusip
03753U106
Sedol
BYTQ6X1
Market capitalization
5.19 B USDMid Cap
52-Week Range
PEG
—
P/E ratio
P/Ee 2026
-39.77
P/Ee 2027
-573.20
P/Ee 2028
32.46
P/Ee 2029
26.24
P/Ee 2030
16.20
P/S
P/Se
5.93
EV/EBIT
93.57
P/B Ratio
14.03
ROE (Return on Equity)
ROA (Return on Assets)
ROCE (Return on Capital Employed)
ROIC (Return on Invested Capital)
2.69 %
Last updated Oct 28, 2026, 1:22 PM

Apellis Pharmaceuticals Ticker

DÜSSELDORF · 1JK.DUFRANKFURT · 1JK.FMUNICH · 1JK.MUNASDAQ · APLS

Apellis Pharmaceuticals FIGI

APLS:US · BBG007KGRPY4APLS:UA · BBG00B6KDS26APLS:UC · BBG00B6KDS35APLS:UN · BBG00B6KDS53APLS:UP · BBG00B6KDS62APLS:UB · BBG00B6KDS80APLS:UM · BBG00B6KDSB6APLS:UX · BBG00B6KDSC5APLS:UD · BBG00B6KDSJ8APLS:UW · BBG00B6KDSL5APLS:UF · BBG00B6KDSM4APLS:VY · BBG00B6KDSN3

All fundamentals and in-depth analysis of Apellis Pharmaceuticals

Our stock analysis for Apellis Pharmaceuticals stock includes important financial indicators such as revenue, profit, P/E ratio, P/S ratio, EBIT, as well as information on dividends. We also assess aspects such as stocks, market capitalization, debt, equity, and liabilities of Apellis Pharmaceuticals. If you are looking for more detailed information on these topics, we offer comprehensive analyses on our subpages.