٨٫٥٣٣٠٨ % | The Vanguard Group, Inc. | ١٤٬٣٥٤٬٣٤٢ | -٣٨١٬٤٧٤ | ٣٠/٦/٢٠٢٤ |
٨٫١٢٠٤٤ % | Wellington Management Company, LLP | ١٣٬٦٦٠٬١٩٦ | -١٬٠٥٤٬٥٣٠ | ٣٠/٦/٢٠٢٤ |
٦٫٤٨١٢٤ % | BlackRock Institutional Trust Company, N.A. | ١٠٬٩٠٢٬٧٣٨ | ٧٧٩٬٠٥٨ | ٣٠/٦/٢٠٢٤ |
٥٫٨٠٠٥٥ % | Farallon Capital Management, L.L.C. | ٩٬٧٥٧٬٦٩٢ | ٢٬٢٤٩٬٨٢٠ | ٣٠/٦/٢٠٢٤ |
٤٫٤٩٩٥٢ % | Baker Bros. Advisors LP | ٧٬٥٦٩٬٠٩٠ | ١٩٬٨٤١ | ٣٠/٦/٢٠٢٤ |
٣٫٧٤٣١٦ % | Nextech Invest, Ltd. | ٦٬٢٩٦٬٧٤٠ | 0 | ٣٠/٦/٢٠٢٤ |
٣٫٥٥٥٥٩ % | BVF Partners L.P. | ٥٬٩٨١٬٢١٢ | 0 | ٣٠/٦/٢٠٢٤ |
٣٫٣٤٣٨٦ % | Fidelity Management & Research Company LLC | ٥٬٦٢٥٬٠٣٥ | ١٬٤٥٨٬٥٩٧ | ٣٠/٦/٢٠٢٤ |
٣٫١٥٤٨٤ % | Alphabet, Inc. | ٥٬٣٠٧٬٠٧٥ | ٥٬٥٦٣ | ٣٠/٦/٢٠٢٤ |
٣٫١٢٦٣٢ % | Paradigm BioCapital Advisors LP | ٥٬٢٥٩٬٠٨٩ | ٢٬٣٤٤٬١١٤ | ٣٠/٦/٢٠٢٤ |
٣٫٠١٤٥٥ % | State Street Global Advisors (US) | ٥٬٠٧١٬٠٦٨ | -٣١٤٬٩٥٢ | ٣٠/٦/٢٠٢٤ |
٣٫٠٠٩٥١ % | T. Rowe Price Associates, Inc. | ٥٬٠٦٢٬٥٩٩ | ٣٩١٬٦١٥ | ٣٠/٦/٢٠٢٤ |
٢٫٩٨٩٦٠ % | Bellevue Asset Management AG | ٥٬٠٢٩٬١٠٠ | -٤٤٬٥٠٠ | ٣٠/٦/٢٠٢٤ |
٢٫٧٥٨٤٢ % | Janus Henderson Investors | ٤٬٦٤٠٬٢١٨ | ٧٢٨٬٠٩٩ | ٣٠/٦/٢٠٢٤ |
٢٫٦١٩٧١ % | Casdin Capital, LLC | ٤٬٤٠٦٬٨٧٥ | -١٬٢١٠٬٧٢٤ | ٣٠/٦/٢٠٢٤ |
٢٫٥٤٣٩٧ % | Boxer Capital, L.L.C. | ٤٬٢٧٩٬٤٦٤ | 0 | ٣٠/٦/٢٠٢٤ |
١٫٩٨٢٩١ % | Geode Capital Management, L.L.C. | ٣٬٣٣٥٬٦٥٦ | ٢٨٢٬٩٦٥ | ٣٠/٦/٢٠٢٤ |
١٫٩٥٦٢٤ % | Woodline Partners LP | ٣٬٢٩٠٬٧٩١ | -٥٠٦٬٣٥٧ | ٣٠/٦/٢٠٢٤ |
١٫٨٣٦٩٢ % | Deerfield Management Company, L.P. | ٣٬٠٩٠٬٠٧٣ | 0 | ٣٠/٦/٢٠٢٤ |
١٫٦٣٣٨٩ % | Andreessen Horowitz | ٢٬٧٤٨٬٥٢٣ | 0 | ٣٠/٦/٢٠٢٤ |
١٫٤٠٥٠٦ % | Balyasny Asset Management LP | ٢٬٣٦٣٬٥٨٤ | ٧٠٨٬٦٨٩ | ٣٠/٦/٢٠٢٤ |
١٫٣٨٥٤١ % | Borisy (Alexis) | ٢٬٣٣٠٬٥٤٢ | ٤٬٢٤٨ | ٢٠/٦/٢٠٢٤ |
١٫٣٢٢٢٥ % | JP Morgan Asset Management | ٢٬٢٢٤٬٢٨٣ | -١٨٢٬٦١٢ | ٣٠/٦/٢٠٢٤ |
١٫٣٠٩٨٨ % | Holocene Advisors, LP | ٢٬٢٠٣٬٤٧٤ | -٢١٨٬٩٣٧ | ٣٠/٦/٢٠٢٤ |
١٫٠٩٨٩٥ % | Norges Bank Investment Management (NBIM) | ١٬٨٤٨٬٦٤٧ | ١٬٥٦٦٬٩٤٢ | ٣٠/٦/٢٠٢٤ |
٠٫٩٨٩٤٩ % | Lord, Abbett & Co. LLC | ١٬٦٦٤٬٥١٦ | -١٣٬٣١٥ | ٣١/٨/٢٠٢٤ |
٠٫٧١٣٣٥ % | Logos Global Management LLC | ١٬٢٠٠٬٠٠٠ | ١٬٢٠٠٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٦٧٩٣٩ % | BlackRock Financial Management, Inc. | ١٬١٤٢٬٨٦٣ | ٧٩٬٧٥٥ | ٣٠/٦/٢٠٢٤ |
٠٫٦٥٩٦٦ % | Charles Schwab Investment Management, Inc. | ١٬١٠٩٬٦٨٤ | ٥٧٬٤٢١ | ٣٠/٦/٢٠٢٤ |
٠٫٦٣٧٢٩ % | Northern Trust Investments, Inc. | ١٬٠٧٢٬٠٥٥ | -٣٧٬٤٠٥ | ٣٠/٦/٢٠٢٤ |
٠٫٦١٥٢٥ % | Goldman Sachs & Company, Inc. | ١٬٠٣٤٬٩٧٢ | ٣٣٤٬٢٩١ | ٣٠/٦/٢٠٢٤ |
٠٫٦٠٣٨٤ % | Invus Public Equities Advisors, LLC | ١٬٠١٥٬٧٧٦ | -٣٠٢٬٨٧٣ | ٣٠/٦/٢٠٢٤ |
٠٫٥٩٢٩٥ % | Frazier Life Sciences Management, L.P. | ٩٩٧٬٤٥٥ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫٥٦٠٦٩ % | Rock Springs Capital Management LP | ٩٤٣٬١٩٥ | ١٩٬٥١٤ | ٣٠/٦/٢٠٢٤ |
٠٫٥٤٣٣٤ % | Hood River Capital Management LLC | ٩١٤٬٠٠٣ | ٩١٤٬٠٠٣ | ٣٠/٦/٢٠٢٤ |
٠٫٥٠٨٩٦ % | Soleus Capital Management, L.P. | ٨٥٦٬١٧٨ | ١٢٧٬٤٧٨ | ٣٠/٦/٢٠٢٤ |
٠٫٥٠٥٠٠ % | Morgan Stanley & Co. LLC | ٨٤٩٬٥٠٥ | ٦٬٧١٦ | ٣٠/٦/٢٠٢٤ |
٠٫٤٨٥١١ % | Marshall Wace LLP | ٨١٦٬٠٥٥ | -٧١٩٬٨٨٥ | ٣٠/٦/٢٠٢٤ |
٠٫٤٤٨٨٢ % | Avidity Partners Management LP | ٧٥٥٬٠٠٠ | ١٢٠٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٤٣٣٦٤ % | Finepoint Capital LP | ٧٢٩٬٤٦٤ | ٥٢٬٣٦٤ | ٣٠/٦/٢٠٢٤ |
٠٫٣٩٣٨٧ % | Candriam Luxembourg S.A. | ٦٦٢٬٥٦٤ | 0 | ٣٠/٩/٢٠٢٤ |
٠٫٣٨٦٨٩ % | Eventide Asset Management, LLC | ٦٥٠٬٨٢٦ | ٢٨٩٬٨٢٦ | ٣٠/٦/٢٠٢٤ |
٠٫٣٧٧٦٧ % | Columbia Threadneedle Investments (UK) | ٦٣٥٬٣١٩ | -٢٤٥٬٣٩١ | ٣٠/٦/٢٠٢٤ |
٠٫٣٦٩٦١ % | JPMorgan Asset Management U.K. Limited | ٦٢١٬٧٥٢ | -٢١٨٬٦٨٠ | ٣٠/٦/٢٠٢٤ |
٠٫٣٥٤٠٧ % | Goldsmith Mark A | ٥٩٥٬٦٠٩ | 0 | ١١/١٠/٢٠٢٤ |
٠٫٣٢٩٥٣ % | Candriam Belgium S.A. | ٥٥٤٬٣٣٤ | -٢٩٬٦١٦ | ٣٠/٦/٢٠٢٤ |
٠٫٣٢٢٥٥ % | Victory Capital Management Inc. | ٥٤٢٬٦٠١ | -٥٧٬٩٨٠ | ٣٠/٦/٢٠٢٤ |
٠٫٣٢١١٢ % | Pzena Investment Management, LLC | ٥٤٠٬١٩٤ | -١٦٠٬٩٧١ | ٣٠/٦/٢٠٢٤ |
٠٫٣٠٨٧١ % | American Century Investment Management, Inc. | ٥١٩٬٣٠٥ | ٥١٩٬٣٠٥ | ٣٠/٦/٢٠٢٤ |
٠٫٣٠٤٣٠ % | Dafna Capital Management, LLC | ٥١١٬٨٩٤ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫٣٠٢٣٢ % | MIC Capital Management UK LLP | ٥٠٨٬٥٦٩ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫٢٩٥٣٧ % | Columbia Threadneedle Investments (US) | ٤٩٦٬٨٧٨ | ٤٩٬١٦٧ | ٣٠/٦/٢٠٢٤ |
٠٫٢٨٧٠٥ % | BlackRock Advisors (UK) Limited | ٤٨٢٬٨٨٣ | ٦١٧ | ٣٠/٩/٢٠٢٤ |
٠٫٢٧٠٥٤ % | Sofinnova Investments, Inc | ٤٥٥٬٠٩٩ | ٤٥٥٬٠٩٩ | ٣٠/٦/٢٠٢٤ |
٠٫٢٦٨٦٢ % | BlackRock Asset Management Ireland Limited | ٤٥١٬٨٧٠ | ١١٥٬٩٩١ | ٣٠/٦/٢٠٢٤ |
٠٫٢٤٩٧٧ % | BlackRock Investment Management, LLC | ٤٢٠٬١٦٩ | ٥٩٬٣٥٠ | ٣٠/٦/٢٠٢٤ |
٠٫٢٤٣٦٠ % | Nuveen LLC | ٤٠٩٬٧٨١ | ٤٥٬٨٥٨ | ٣٠/٦/٢٠٢٤ |
٠٫٢٤٣٠٤ % | Citadel Advisors LLC | ٤٠٨٬٨٤٢ | -١٧٩٬٢٤٦ | ٣٠/٦/٢٠٢٤ |
٠٫٢٣٧٤٨ % | Goldman Sachs Asset Management, L.P. | ٣٩٩٬٤٨٩ | -١٣٬٢٢١ | ٣٠/٦/٢٠٢٤ |
٠٫٢٣٢٦٩ % | BlackRock Investment Management (UK) Ltd. | ٣٩١٬٤٣٩ | ٤٤٬٦٢٤ | ٣٠/٦/٢٠٢٤ |
٠٫٢٣٢١٩ % | Dimensional Fund Advisors, L.P. | ٣٩٠٬٥٨٣ | -٩٤٠٬٦٧٦ | ٣٠/٦/٢٠٢٤ |
٠٫٢٢٦٥١ % | BofA Global Research (US) | ٣٨١٬٠٤١ | -١٤٠٬٣٥٥ | ٣٠/٦/٢٠٢٤ |
٠٫٢٢٦٢٥ % | Jane Street Capital, L.L.C. | ٣٨٠٬٥٩٤ | ٢٥١٬١٢٧ | ٣٠/٦/٢٠٢٤ |
٠٫٢١٥٤٤ % | BNY Mellon Asset Management | ٣٦٢٬٤١٦ | ٤٦٬٥٨٩ | ٣٠/٦/٢٠٢٤ |
٠٫٢٠١٠٤ % | Partners HealthCare System, Inc | ٣٣٨٬١٩١ | 0 | ٣٠/٩/٢٠٢٤ |
٠٫١٩٥٨٩ % | First Turn Management, LLC | ٣٢٩٬٥١٩ | ٣٢٩٬٥١٩ | ٣٠/٦/٢٠٢٤ |
٠٫١٩٣٢٠ % | Integral Health Asset Management, LLC | ٣٢٥٬٠٠٠ | -٩٥٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٩٠٠٠ % | AllianceBernstein L.P. | ٣١٩٬٦١٨ | -٣٬٧٤٦ | ٣٠/٦/٢٠٢٤ |
٠٫١٨٢٧٣ % | Columbia Wanger Asset Management, LLC | ٣٠٧٬٣٨٧ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫١٧٢٠٣ % | MPM BioImpact LLC | ٢٨٩٬٣٩٦ | ١٦٬١٧٩ | ٣٠/٦/٢٠٢٤ |
٠٫١٦٨٠٨ % | AHL Partners LLP | ٢٨٢٬٧٤٦ | ٢٥٣٬٤٤٩ | ٣٠/٦/٢٠٢٤ |
٠٫١٦٥٢٦ % | Mubadala Investment Company PJSC | ٢٧٨٬٠٠٠ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫١٦٠٢١ % | Ensign Peak Advisors, Inc. | ٢٦٩٬٥٠٤ | ٢٢٩٬٧٢١ | ٣٠/٦/٢٠٢٤ |
٠٫١٥٩٨٩ % | Mellon Investments Corporation | ٢٦٨٬٩٦٢ | ٦٥٬٢١٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٥٦٣٩ % | Voya Investment Management LLC | ٢٦٣٬٠٧٩ | -٢٠٬٥٥٤ | ٣٠/٦/٢٠٢٤ |
٠٫١٤٨٧٣ % | TD Asset Management Inc. | ٢٥٠٬١٩٤ | -٤٬٤٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٤٨١٣ % | Qube Research & Technologies Ltd | ٢٤٩٬١٨٨ | ٨١٬٧٠٨ | ٣٠/٦/٢٠٢٤ |
٠٫١٤٤٧٢ % | Bessemer Trust Company, N.A. (US) | ٢٤٣٬٤٤٢ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫١٣٥٨٧ % | Rhumbline Advisers Ltd. Partnership | ٢٢٨٬٥٦٧ | ١٩٬٢٥٧ | ٣٠/٦/٢٠٢٤ |
٠٫١٣٥٨٤ % | Susquehanna Fundamental Investments, LLC | ٢٢٨٬٥١٣ | ٢٢٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٣٥٤٩ % | Point72 Asset Management, L.P. | ٢٢٧٬٩٢٢ | ٢٢٧٬٩٢٢ | ٣٠/٦/٢٠٢٤ |
٠٫١٣٥١٦ % | HSBC Private Bank (Suisse) S.A. | ٢٢٧٬٣٦٥ | ١٩٬٠٨١ | ٣١/٨/٢٠٢٤ |
٠٫١٣٤٨٤ % | Schweizerische Nationalbank | ٢٢٦٬٨٣١ | ٢٦٬٧٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٣٣٢٤ % | Walleye Capital LLC | ٢٢٤٬١٤٣ | ١٨٩٬١٨٦ | ٣٠/٦/٢٠٢٤ |
٠٫١٣٠٩٥ % | TwinBeech Capital LP | ٢٢٠٬٢٨٩ | ٢٢٠٬٢٨٩ | ٣٠/٦/٢٠٢٤ |
٠٫١٢٩٤٥ % | UBS Financial Services, Inc. | ٢١٧٬٧٦٣ | -٨٧٬٢١٦ | ٣٠/٦/٢٠٢٤ |
٠٫١٢٦٢٤ % | Manulife Investment Management (North America) Limited | ٢١٢٬٣٦٨ | ١٣٬٣١٨ | ٣٠/٦/٢٠٢٤ |
٠٫١١٣٢٥ % | Raymond James & Associates, Inc. | ١٩٠٬٥٠٥ | ١١٦٬١٣٥ | ٣٠/٩/٢٠٢٤ |
٠٫١١٠٣٥ % | Rafferty Asset Management LLC | ١٨٥٬٦٣٧ | -٩٨٬٧١٥ | ٣٠/٦/٢٠٢٤ |
٠٫١٠١٠٦ % | Adage Capital Management, L.P. | ١٧٠٬٠٠٠ | -٣٠٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٠٩٧٠٤ % | Readystate Asset Management LP | ١٦٣٬٢٤١ | ٩٥٬٩٤١ | ٣٠/٦/٢٠٢٤ |
٠٫٠٩٤١٣ % | Kelsey (Stephen Michael) | ١٥٨٬٣٤٥ | 0 | ١٤/١٠/٢٠٢٤ |
٠٫٠٩٤٠٠ % | Nicholas Investment Partners, L.P. | ١٥٨٬١٣٢ | ١٤٢٬٠٤٤ | ٣٠/٦/٢٠٢٤ |
٠٫٠٩١٥٨ % | T. Rowe Price International Ltd | ١٥٤٬٠٦٠ | ١٠٬٧٣٤ | ٣٠/٦/٢٠٢٤ |
٠٫٠٨٤٤٦ % | Neuberger Berman, LLC | ١٤٢٬٠٨٧ | -١٬٢٧٢ | ٣٠/٦/٢٠٢٤ |
٠٫٠٨١٧٧ % | JPMorgan Private Bank (United States) | ١٣٧٬٥٥٩ | -١٬٣٧٣ | ٣٠/٦/٢٠٢٤ |
٠٫٠٨٠٠٩ % | Conestoga Capital Advisors, LLC | ١٣٤٬٧٢١ | -١٬٢٩٦ | ٣١/٣/٢٠٢٤ |
٠٫٠٧٩٠٦ % | Acuta Capital Partners, LLC | ١٣٣٬٠٠٠ | -١٠٬٧٧٧ | ٣٠/٦/٢٠٢٤ |
٠٫٠٧٨٤٤ % | J.P. Morgan Securities plc | ١٣١٬٩٤٤ | ٩٥٬٩١٨ | ٣٠/٦/٢٠٢٤ |
٠٫٠٧٧٧١ % | Legal & General Investment Management Ltd. | ١٣٠٬٧٢٥ | ٢٤٬٥٩٦ | ٣٠/٦/٢٠٢٤ |